Peroxiredoxin 2 Proteine (PRDX2)

PRDX2 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Zusätzlich bieten wir Ihnen Peroxiredoxin 2 Antikörper (151) und Peroxiredoxin 2 Kits (44) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PRDX2 7001 P32119
PRDX2 21672 Q61171
PRDX2 29338 P35704
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Showing 10 out of 31 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Baculovirus infected Insect Cells Human His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Chinese Hamster His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Cynomolgus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human Unkonjugiert 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
Escherichia coli (E. coli) Human Unkonjugiert Figure annotation denotes ug of protein loaded and % gel used. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
Escherichia coli (E. coli) Human Unkonjugiert 100 μg Anmelden zum Anzeigen 2 bis 3 Tage

PRDX2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus) ,

Am meisten referenzierte Peroxiredoxin 2 Proteine

  1. Human Peroxiredoxin 2 Protein expressed in Wheat germ - ABIN1316151 : Desmetz, Bascoul-Mollevi, Rochaix, Lamy, Kramar, Rouanet, Maudelonde, Mangé, Solassol: Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)

  2. Mouse (Murine) Peroxiredoxin 2 Protein expressed in Escherichia coli (E. coli) - ABIN2121834 : Zhao, Du, Zhou, Liu, Gu, Long: Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages. in PLoS ONE 2016 (PubMed)

Weitere Proteine zu Peroxiredoxin 2 (PRDX2) Interaktionspartnern

Human Peroxiredoxin 2 (PRDX2) Interaktionspartner

  1. Association and oligomerization of Prx (zeige PRDX6 Proteine) II could take part in recovery and protection of the CK BB enzyme activity from inactivation during heat-induced stress.

  2. Prx (zeige PRDX6 Proteine) II plays a key role in the cancer stem cell self-renewal of hepatocellular carcinoma cells through redox regulation.

  3. Peroxiredoxin-2 (PRDX2) and hemoglobin (zeige HBB Proteine)-subunits proteins, which are closely involved in the response to oxidative stress.

  4. High PRDX2 expression is associated with colorectal cancer progression.

  5. Knockdown of forkhead Box M1 (FoxM1 (zeige FOXM1 Proteine)) reduced Prx (zeige PRDX6 Proteine) II levels in H-ras (zeige HRAS Proteine)(G12V)-hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) cells, indicating FoxM1 (zeige FOXM1 Proteine) as a direct transcription factor of Prx (zeige PRDX6 Proteine) II in HCC (zeige FAM126A Proteine).

  6. Prx1 (zeige PRDX1 Proteine) and Prx2 are likely targets of urate hydroperoxide in cells. Oxidation of Prxs by urate hydroperoxide might affect cell function and be partially responsible for the pro-oxidant and pro-inflammatory effects of uric acid.

  7. Data indicate that peroxiredoxin 2 (PRDX2) was upregulated in white matter multiple sclerosis (MS) lesions mainly in astrocytes, and its expression level was positively correlated with the degree of inflammation and oxidative stress, and suggest that PRDX2 expression contributes to the resistance of astrocytes against oxidative damage.

  8. The levels of expression of carbonic anhydrase 2 (zeige CA2 Proteine), catalase (zeige CAT Proteine), and PRDX2 in the nipple discharge were significantly increased in breast ductal carcinoma patients as compared to controls.

  9. Activation of PRX1 (zeige PRDX1 Proteine) and -2 indicate cold atmospheric plasma affects redox homeostasis in osteosarcoma cells

  10. ig-h3, Peroxiredoxin-2, and NRF2 (zeige GABPA Proteine) have roles in cervical carcinogenesis

Mouse (Murine) Peroxiredoxin 2 (PRDX2) Interaktionspartner

  1. one of the antioxidant enzymes, Prdx-2, was abundantly nitrosylated and temporarily reduced in antioxidant activity, causing transient endogenous hydrogen peroxide (H2O2) accumulation and subsequent X-box binding protein-1s/phosphatidylinositol 3-kinase pathway activation.Prdx-2 nitrosylation could be a potent strategy to affect the pluripotent stem cell-derived cardiomyogenesis.

  2. Oxidative stress promotes PRX2 (zeige PRRX2 Proteine) and PRX3 (zeige PRDX3 Proteine) hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.

  3. The ventral signal observed for Prdx2 from early stages colocalized with motor neuron markers Isl1 (zeige ISL1 Proteine)/2 and FoxP1 (zeige FOXP1 Proteine) and strong ventral signal colocalizing with Isl1 (zeige ISL1 Proteine)/2 was observed in all rostrocaudal segments of the spinal cord.

  4. Prx2 (zeige PRRX2 Proteine) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (zeige GRX1 Proteine) provide an alternative mechanism to thioredoxin (zeige TXN Proteine) and thioredoxin reductase for Prx2 (zeige PRRX2 Proteine) recycling.

  5. elevation in hyperoxidized Prxs, notably Prx2 (zeige PRRX2 Proteine) and Prx3 (zeige PRDX3 Proteine), was observed in several organs from SOD1 (zeige SOD1 Proteine)-deficient mice. However, a SOD1 (zeige SOD1 Proteine) deficiency had no impact on the wheel-running activity of the mice

  6. PrxII functions as a protective antioxidant enzyme against collagen-stimulated platelet activation and platelet-dependent thrombosis

  7. Prx I and Prx II appear to have a tight association with the mechanism underlying the protection of ESC stemness in developing teratomas.

  8. results suggest that inactivation of PrxII is important for the stability of FoxO1 (zeige FOXO1 Proteine) protein, which subsequently mediates Foxp3 (zeige FOXP3 Proteine)( ) Treg cell development, thereby attenuating colonic inflammation

  9. PRDX2 neutralizes hydrogen peroxide generated in vivo under the transient hypoxic conditions experienced as erythrocytes pass through the microcirculation.

  10. PRX2 (zeige PRRX2 Proteine) battles poly(ADP-ribose) polymerase 1 (zeige PARP1 Proteine)- and p53 (zeige TP53 Proteine)-dependent prodeath pathways after ischemic injury

Peroxiredoxin 2 (PRDX2) Protein Überblick

Protein Überblick

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Genbezeichner und Symbole assoziert mit Peroxiredoxin 2 Proteine (PRDX2)

  • peroxiredoxin 2 (PRDX2)
  • peroxiredoxin 2 (Prdx2)
  • peroxiredoxin 2 L homeolog (prdx2.L)
  • AL022839 Protein
  • Band-8 Protein
  • NKEF-B Protein
  • nkefb Protein
  • PRP Protein
  • prx-2 Protein
  • prx2 Protein
  • prxii Protein
  • PTX1 Protein
  • tdpx1 Protein
  • TDX1 Protein
  • Torin Protein
  • TPx Protein
  • TPx-B Protein
  • tpx1 Protein
  • TR Protein
  • TSA Protein

Bezeichner auf Proteinebene für Peroxiredoxin 2 Proteine (PRDX2)

natural killer cell-enhancing factor B , peroxiredoxin-2 , thiol-specific antioxidant 1 , thioredoxin peroxidase 1 , thioredoxin-dependent peroxide reductase 1 , torin , Calpromotin , Prx II-1 , Trx dependent peroxide reductase 1 , protector protein , thiol specific antioxidant protein , thiol-specific antioxidant protein , thioredoxin dependent peroxide reductase 1 , thioredoxin reductase , TSA

100063348 Equus caballus
7001 Homo sapiens
21672 Mus musculus
29338 Rattus norvegicus
443840 Xenopus laevis
100512521 Sus scrofa
286793 Bos taurus
100715787 Cavia porcellus
100307046 Ovis aries
100172251 Pongo abelii
100689349 Cricetulus griseus
100856470 Canis lupus familiaris
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