PHD Finger Protein 17 Proteine (PHF17)

Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Zusätzlich bieten wir Ihnen PHD Finger Protein 17 Antikörper (56) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PHF17 79960 Q6IE81
PHF17 269424 Q6ZPI0
Ratte PHF17 PHF17 310352  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg 11 bis 12 Tage
$414.29
Details

PHF17 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu PHD Finger Protein 17 (PHF17) Interaktionspartnern

Zebrafish PHD Finger Protein 17 (PHF17) Interaktionspartner

  1. The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate beta-catenin signaling.

Human PHD Finger Protein 17 (PHF17) Interaktionspartner

  1. results indicate that the N-terminal region of JADE1 functions as a platform that brings together the catalytic HBO1 subunit with its cognate H3-H4 substrate for histone acetylation

  2. identification of SNPs within the IQCJ, NXPH1, PHF17 and MYB genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation

  3. A genome-wide association study (GWAS) identified loci associated with the plasma triglyceride (TG) response to omega-3 fatty acid (FA) supplementation in IQCJ, NXPH1, PHF17 and MYB.

  4. JADE1 expression has a role in colon cancers, renal carcinomas, and in acute kidney injuries and regeneration. (Review)

  5. Interactome analyses revealed that the Jade-1S mutant unable to be phosphorylated by CK1alpha has an increased binding affinity to proteins involved in chromatin remodelling, histone deacetylation, transcriptional repression, and ribosome biogenesis.

  6. JADE1S protein localized to centrosomes in interphase and mitotic cells, and to the midbody during cytokinesis.

  7. Casein kinase 1 alpha specifically phosphorylates Jade-1 at an unprimed SLS phosphorylation site.

  8. Increase in the number of cells with cytoplasmic JADE1S correlated with activation of tubular cell proliferation and inversely correlated with the number of cells with nuclear JADE1S, supporting role of HBO1-JADE1 shuttling during organ regeneration.

  9. lncRNA-JADE is a key functional link that connects the DDR to histone H4 acetylation, and that dysregulation of lncRNA-JADE may contribute to breast tumorigenesis.

  10. Reduced Jade-1 expression is associated with clear-cell renal cell carcinomas.

  11. The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate beta-catenin signaling.

  12. RCC with a low expression of Jade-1 is associated with a poor outcome and decreased survival

  13. Jade-1 protein is a novel candidate regulatory factor in Von Hippel Lindau-mediated renal tumor suppression

  14. Jade-1 is a novel candidate transcriptional co-activator associated with HAT activity and may play a key role in the pathogenesis of renal cancer and von Hippel-Lindau disease

  15. Jade-1 may suppress renal cancer cell growth in part by increasing apoptosis.

  16. Jade-1/1L are crucial co-factors for HBO1-mediated histone H4 acetylation

  17. The pVHL tumour suppressor and the Wnt tumorigenesis pathway are therefore directly linked through Jade-1.

Mouse (Murine) PHD Finger Protein 17 (PHF17) Interaktionspartner

  1. Interactome analyses revealed that the Jade-1S mutant unable to be phosphorylated by CK1alpha has an increased binding affinity to proteins involved in chromatin remodelling, histone deacetylation, transcriptional repression, and ribosome biogenesis.

  2. lncRNA-JADE is a key functional link that connects the DDR to histone H4 acetylation, and that dysregulation of lncRNA-JADE may contribute to breast tumorigenesis.

  3. exhibits a regulated expression during embryogenesis and localizes to the nucleus and/or cytoplasm of different cell types

PHD Finger Protein 17 (PHF17) Protein Überblick

Protein Überblick

Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor (By similarity).

Genbezeichner und Symbole assoziert mit PHD Finger Protein 17 Proteine (PHF17)

  • jade family PHD finger 1 (JADE1)
  • jade family PHD finger 1 (jade1)
  • jade family PHD finger 1 S homeolog (jade1.S)
  • jade family PHD finger 1 (Jade1)
  • AU041499 Protein
  • D530048A03Rik Protein
  • fi11a04 Protein
  • Jade1 Protein
  • mKIAA1807 Protein
  • wu:fi11a04 Protein
  • zgc:55323 Protein

Bezeichner auf Proteinebene für PHD Finger Protein 17 Proteine (PHF17)

PHD finger protein 17 , protein Jade-1-like , protein Jade-1 , PHD protein Jade-1 , gene for apoptosis and differentiation in epithelia , Jade1 PHD finger protein

GENE ID SPEZIES
100347258 Oryctolagus cuniculus
100435378 Pongo abelii
327437 Danio rerio
443866 Xenopus laevis
422502 Gallus gallus
79960 Homo sapiens
509264 Bos taurus
269424 Mus musculus
310352 Rattus norvegicus
483830 Canis lupus familiaris
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