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TP53AIP1 is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. Zusätzlich bieten wir Ihnen TP53AIP1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal TP53AIP1 Primary Antibody für ICC, ELISA - ABIN1002964
Oda, Arakawa, Tanaka, Matsuda, Tanikawa, Mori, Nishimori, Tamai, Tokino, Nakamura, Taya: p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. in Cell 2000
Show all 4 Pubmed References
Human Polyclonal TP53AIP1 Primary Antibody für ELISA, WB - ABIN566226
Igarashi, Hirano, Yahagi, Saika, Ishihara: Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A. in Clinical immunology (Orlando, Fla.) 2014
Data indicate that p53-regulated apoptosis-inducing protein 1 (p53AIP1) inhibits the proliferation of PC-3M cells, arrests cell cycle at S/G2 (zeige STRN3 Antikörper)-M phase, decreases the abilities of invasion and migration and promotes cell apoptosis.
These studies indicate the critical role of p53AIP1 under DNA damaging stresses for cell fate determination in rheumatoid arthritis-fibroblast-like synovioctes containing the p53R248Q mutation.
Apak (zeige ZNF420 Antikörper) competes with p53 (zeige TP53 Antikörper) for binding to inhibit p53AIP1 expression.
large sample size of the combined cohort rejects a high-risk effect greater than 2.2 and indicates a limited role of TP53AIP1 in prostate cancer predisposition
p53AIP1 regulates the mitochondrial apoptotic pathway.
The expression of Ki67 (zeige MKI67 Antikörper) and p53 (zeige TP53 Antikörper) in various forms of leukoplakia point to the increasing instability of the genome in parallel with the severity of leukoplakia.
expression of the p53 (zeige TP53 Antikörper) mutant, R248Q, in liver cancer cells may enhance their drug resistance and upregulation of P-glycoprotein activity may contribute to this protective effect.
Roscovitine induced up-regulation of p53AIP1 protein and the depolarization of mitochondrial potential.
p53AIP1 gene is important for non-small cell lung cancer progression and may be a possible prognostic marker
Insufficient expression of p53AIP1 may play a role in gastric carcinogenesis in patients infected with H. pylori infection.
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
p53-regulated apoptosis-inducing protein 1