Ornithine Decarboxylase Antizyme 1 (OAZ1) ELISA Kits

Human Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartner

1. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN).

2. Results show that ornithine decarboxylase antizyme 1 (OAZ1) simultaneously inhibits the proliferation and induces the differentiation of oral cancer cells.

3. To further understand its functions in CML (zeige BCR ELISA Kits) pathogenesis, OAZ1 was overexpressed, and PCR array analysis was used to monitor the expression of key genes commonly involved in leukemia development.

4. Gene expression studies have identified altered expression of ornithine decarboxylase antizyme 1 in suicide completers with a history of mood disorders.

5. In the absence of amino acids, mTORC1 is inhibited, whereas mTORC2 is activated, leading to the inhibition of global protein synthesis and increased AZ1 synthesis via a cap-independent mechanism.

6. AZ_95-176 is the minimal AZ peptide that is fully functioning in the binding of ODC (zeige ODC1 ELISA Kits) and AZI and inhibition of their function.

7. the differences in residues 125 and 140 in ODC and AZI are responsible for the differential antizyme-binding affinities

8. Data show that OAZ promotes the removal of Mps1 (zeige IDUA ELISA Kits) from centrosomes, and centrosome overproduction caused by reducing OAZ activity requires Mps1 (zeige IDUA ELISA Kits).

9. These data together demonstrate the existence of a c-Jun (zeige JUN ELISA Kits)-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

10. Human AZI is capable of acting as a general inhibitor for all members of the antizyme family.

Mouse (Murine) Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartner

1. Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ).

2. we have generated transgenic mice overexpressing mouse antizyme 1 gene under its own regulatory sequences

3. Ornithine decarboxylase antizyme expression reduces tumor incidence, multiplicity and size even in the absence of p53 (zeige TP53 ELISA Kits).

4. The activity of AZ1 was low in the virgin and involuting stages, but increased markedly during late pregnancy and early lactation.

5. These data together demonstrate the existence of a c-Jun (zeige JUN ELISA Kits)-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

6. Testosterone treatment enhanced AZ1 and N1-SSAT (zeige SAT1 ELISA Kits) mRNA levels in a time-dependent manner

7. antizyme and glycosaminoglycans have roles in polyamine transport

8. OAZ can alter the intensity and duration of the BMP4 (zeige BMP4 ELISA Kits) stimulus through Smad6 (zeige SMAD6 ELISA Kits)

9. Az-1 has a central and meaningful role in modulation of polyamine homeostasis, and in regulating cellular proliferation and transformation properties.

10. The data-driven docking results suggest that both proteins occupy the same binding site on Az1, with Az1 binding within a large groove in antizyme inhibitor (AzI) and Ornithine Decarboxylase (ODC (zeige ODC1 ELISA Kits)).

Xenopus laevis Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartner

1. antizyme expression requires programmed,+1 ribosomal frameshifting