anti-Opsin 4 (OPN4) Antikörper

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. Zusätzlich bieten wir Ihnen OPN4 Kits (4) und OPN4 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
OPN4 192223 Q8R456
OPN4 94233 Q9UHM6
OPN4 30044 Q9QXZ9
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Top anti-OPN4 Antikörper auf

Showing 10 out of 23 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Melanopsin expression in HEK293T (A) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from COLO cells, using OPN4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ELISA, IF, WB Western Blot (WB) analysis of specific lysis using Melanopsin Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC, WB Figure 1 shows immunofluorescence staining of melanopsin in rat retinal ganglion cells using ABIN261558. Immunocytochemistry/Immunofluorescence: Melanopsin Antibody [ABIN2615580] - Staining in rat retinal ganglion cells. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IF, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 7 bis 8 Tage
Human Kaninchen Unkonjugiert IF, WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: Melanopsin Antibody [NBP1-92105] - Staining of human placenta shows strong membrane positivity in trophoblastic cells. 0.1 mL Anmelden zum Anzeigen 18 bis 20 Tage
Maus Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage

OPN4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus)

Human ,

Mouse (Murine)

Weitere Antikörper gegen OPN4 Interaktionspartner

Zebrafish Opsin 4 (OPN4) Interaktionspartner

  1. Opn4m2 labeling shows nuclear localization, which did not change in response to light. opn4m1, opn4m2, gr, per1b, and cry1b presented an oscillatory profile of expression in LD condition. In both DD and LD condition, dexamethasone (DEX) treatment shifted the peak expression of per1b and cry1b transcripts

  2. Melanopsin photostimulation triggers the phosphoinositide pathway through activation of a G-Protein, G11 (zeige STK19 Antikörper).

  3. The opn4a gene is expressed continuously from 1 to 3 dpf in the presumptive preoptic area, as defined by coexpression of the orthopedia homolog (otp (zeige OTP Antikörper)) gene.

  4. description of the discovery and functional characterisation of a new melanopsin gene in fish, bird, and amphibian genomes, demonstrating that vertebrates have evolved two quite separate melanopsins

Turkey Opsin 4 (OPN4) Interaktionspartner

  1. Expressed locally in the premammillary nucleus of the hypothalamus in temperate zone birds, melanopsin is an important regulator of reproductive activity.

Human Opsin 4 (OPN4) Interaktionspartner

  1. The wide distribution of OPN4 in central areas of the human brain evokes a question whether ambient light has important straight targets in the human brain outside the retinohypothalamic tract.

  2. Trait-like individual differences in the melanopsin phototransduction circuitry contribute to individual differences in sleep timing. Blue light-sensitive young individuals are more prone to delayed sleep.

  3. The light-induced FOS response in melanopsin expressing HEK (zeige EPHA3 Antikörper)-293 cells is correlated with melanopsin quantity and dependent on light duration and irradiance.

  4. By broadening the tuning of intrinsically photosensitive retinal ganglion cells, melanopsin tristability produces signal integration.

  5. The response of the human pupil to the separate stimulation of the cones and melanopsin at a range of temporal frequencies under photopic conditions, was measured.

  6. Studied OPN4*Ile394Thr gene polymorphism in association with sleep/wake timing.

  7. The results of this study showed that the post illumination pupil response varied on the basis of OPN4 I394T genotype among individuals with seasonal affective disorder.

  8. Studied the association between melanopsin gene polymorphism and pupillary light reflex under diverse photic conditions, including different intensities and wavelengths.

  9. A comparison of melanopsin with the mechanisms documented for vertebrate (bovine) and invertebrate (squid) visual photoreceptors shows that such a mechanism is not affected by the diversity of the three chromophore cavities.

  10. An action spectrum for the calcium response in cells expressing human melanopsin had the predicted form for an opsin (zeige RHO Antikörper) : vitamin A1 pigment and peaked at 479 nm. The G-protein selectivity and spectral sensitivity of human melanopsin is similar to that previously described for rodents.

Mouse (Murine) Opsin 4 (OPN4) Interaktionspartner

  1. Melanopsin contributes to irradiance modulation of narrowband oscillations in the retina and dorsal lateral geniculate nucleus.

  2. discovery that amino acid sequence features of melanopsin protein contribute to the functional properties of the intrinsically photosensitive retinal ganglion cells

  3. When compared with wildtype responses, sleep onset in melanopsin (OPN4-/-) mice was significantly advanced under blue light, whereas under violet and green light it was significantly delayed.

  4. Melanopsin overexpression in RGCs enhanced the amplitude and duration of their light response, and silencing them with Kir2.1 (zeige KCNJ2 Antikörper) significantly suppressed the increased mTOR (zeige FRAP1 Antikörper) signaling and axon regeneration that were induced by melanopsin

  5. mice null for melanopsin (Opn4-/-), lost significantly more weight than wild-type controls or mice lacking rod and cone photoreceptors.

  6. These results suggest GRK2 (zeige ADRBK1 Antikörper) contributes to melanopsin deactivation, but that other mechanisms account for most of modulation of melanopsin activity in ipRGCs.

  7. Using a combination of conventional knockout, chemogenetic, and receptor-silent substitution manipulations, we continued to show that, over higher irradiances, this increase in firing originates with inner-retinal melanopsin photoreception

  8. Opn4 mediates wavelength-specific, light-dependent vascular relaxation.

  9. Data indicate that retinal molecular circadian clock can be entrained by lighting cycles in vitro, but that rods, cones, and melanopsin (Opn4) are not required for this entrainment.

  10. critical phosphorylation sites on the carboxy tail of melanopsin

OPN4 Antigen-Profil

Protein Überblick

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit anti-Opsin 4 (OPN4) Antikörper

  • opsin 4.1 (opn4.1) Antikörper
  • opsin 4 (OPN4) Antikörper
  • melanopsin (LOC100303707) Antikörper
  • melanopsin-B-like L homeolog (LOC100485437.L) Antikörper
  • opsin 4a (melanopsin) (opn4a) Antikörper
  • opsin 4 (Opn4) Antikörper
  • opsin 4 (melanopsin) (Opn4) Antikörper
  • 1110007J02Rik Antikörper
  • cOpn4L Antikörper
  • Gm533 Antikörper
  • melanopsin Antikörper
  • MOP Antikörper
  • opn4 Antikörper
  • OPN4-2 Antikörper
  • opn4-A Antikörper
  • opn4d Antikörper
  • opn4l Antikörper
  • opn4m2 Antikörper
  • Xmop Antikörper

Bezeichner auf Proteinebene für anti-Opsin 4 (OPN4) Antikörper

melanopsin opn4m2 , melanopsin-like , opn4c , opsin 4 (melanopsin) , opsin 4, like , melanopsin , melanopsin 2 , opsin 4 like , putative Opsin 4 , opsin 4 , putative photopigment melanopsin , mammalian-like melanopsin , melanopsin opn4m1 , melanopsin-A , melanopsin-M , opn4m1 , opsin-4-A , opsin-4M , opsin-4

352918 Danio rerio
423609 Gallus gallus
515152 Bos taurus
611027 Canis lupus familiaris
735531 Pan troglodytes
100303707 Meleagris gallopavo
373689 Xenopus laevis
571624 Danio rerio
192223 Rattus norvegicus
94233 Homo sapiens
493921 Felis catus
30044 Mus musculus
Ausgewählte Anbieter für anti-OPN4 (OPN4) Antikörper
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