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a class of opioid receptors; show selective affinity for the endogenous opioid dynorphin. Zusätzlich bieten wir Ihnen Opioid Receptor, kappa 1 Kits (5) und Opioid Receptor, kappa 1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal OPRK1 Primary Antibody für ELISA, ICC - ABIN4329272
Li, Chen, Liu-Chen: N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway. in Biochemistry 2007
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Human Polyclonal OPRK1 Primary Antibody für WB - ABIN1881595
Bruijnzeel: kappa-Opioid receptor signaling and brain reward function. in Brain research reviews 2009
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Human Polyclonal OPRK1 Primary Antibody für WB - ABIN317765
Niwa, Rowbotham, Lambert: Evaluation of primary opioid receptor antibodies for use in western blotting. in British journal of anaesthesia 2012
ZFOR3 is a unique model to study kappa opioid receptor functionality
These findings provide evidence that previously demonstrated KOR-mediated reduction in intraocular pressure could be caused, in part, by NO production in both the ciliary body and the trabecular meshwork.
The OPRK1/kappa-opioid receptor pathway was found to be downregulated in lesional skin of psoriasis, correlating positively with itch sensation.
Functional activity of Dynorphin 1-17 and fragments (1-6, 1-7 and 1-9) were screened over a range of concentrations against forskolin stimulated human embryonic kidney 293 (HEK (zeige EPHA3 Antikörper)) cells stably transfected with one of KOP (zeige SPINT2 Antikörper), MOP (zeige NLN Antikörper) or DOP (zeige COPB2 Antikörper)
These results indicate that KOR can form a heterodimer with B2R (zeige BDKRB2 Antikörper) and this leads to increased protein kinase A activity by the CREB (zeige CREB1 Antikörper) signaling pathway, leading to a significant increase in cell proliferation.
that promoter fragments of OPRK1 and OPRM1 (zeige OPRM1 Antikörper) were able to upregulate gene expression with mild cognitive impairment
Heterodimerization of the kappa opioid receptor and neurotensin receptor 1 contributes to a novel beta-arrestin-2 (zeige ARRB2 Antikörper)-signaling pathway.
Hypoxia inducible factor-1alpha (HIF-1alpha (zeige HIF1A Antikörper)) siRNA knocked down the increase of endogenous HIF-1alpha (zeige HIF1A Antikörper) messages and diminished the desferrioxamine (DFO)-induced increase of kappa-opioid receptor (hKOR) expression.
genetic association studies in a population in Denmark: Data suggest that carriers/heterozygotes of the C allele (CC/CT) of OPRK SNP rs6473799 report a 30.4% higher mechanical visceral pain tolerance threshold than non-carriers.
Molecular switches of the kappa opioid receptor triggered by 6'-GNTI (zeige MGAT1 Antikörper) and 5'-GNTI (zeige MGAT1 Antikörper) have been described.
The study successfully developed a population PKPD model for oxycodone across three experimental pain types and investigated the association between 18 SNPs across all three opioid receptor genes (OPRM1 (zeige OPRM1 Antikörper), OPRK1, OPRD1 (zeige OPRD1 Antikörper)) and analgesic response from oxycodone. None of the selected polymorphisms were significantly associated with analgesic response of oxycodone.
findings suggest that SNPs in opioid receptors and the PNOC (zeige PNOC Antikörper) genes are associated with NAS (zeige SCN9A Antikörper) severity.
The kappa opioid receptor was identified as a key player mediating the effects of buprenorphine in tests sensitive to antidepressant drugs in mice.
This study provides the first evidence for a time- and learning-dependent property of neocortical kappa opioid receptor in facilitating acquisition and consolidation of associative memories.
triazole 1.1 retained the antinociceptive and antipruritic efficacies of a conventional KOR agonist, yet it did not induce sedation or reductions in dopamine release in mice, nor did it produce dysphoria as determined by intracranial self-stimulation
This study reports a cluster of compounds that are highly effective in enhancing remyelination and identifies kappa-opioid receptor (KOR) as a positive regulator for oligodendroglial differentiation, implicating KOR agonism as a potential strategy to accelerate remyelination.
GRK2 (zeige ADRBK1 Antikörper) upregulation causes kappa-opioid receptor desensitization in diabetic heart
Study showed that Dyn (zeige PDYN Antikörper)-A, the endogenous kappa opioid receptor agonist, significantly hyperpolarized and inhibited neurons in the paraventricular nucleus of mouse thalamus
Suggest that mixed cardiac ion channel blockade my mediated the antiarrhythmia actions of kappa-opioid receptor antagonist PD117,302.
Anti-nociception mediated by a KOR agonist is blocked by a DOR agonist
Findings suggest that activation of kappa opioid receptor (kappa-opioid receptor) reduces hyperglycemia in streptozotocin-induced diabetic mice.
findings show that, during prolonged heroin abstinence, delta opioid receptors regulate hedonic homeostasis, while mu opioid receptor (zeige OPRM1 Antikörper) signaling in serotonergic pathways and kappa opioid receptors together control social behaviors
a class of opioid receptors\; show selective affinity for the endogenous opioid dynorphin
, kappa-type opioid receptor
, opioid receptor, kappa 1
, kappa opioid receptor
, Opiate receptor, kappa-1
, opioid receptor, kappa 2