anti-One Cut Homeobox 2 (ONECUT2) Antikörper

ONECUT2 encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. Zusätzlich bieten wir Ihnen One Cut Homeobox 2 Kits (18) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ONECUT2 225631 Q6XBJ3
ONECUT2 9480 O95948
ONECUT2 307376  
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Top anti-One Cut Homeobox 2 Antikörper auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert WB WB Suggested Anti-ONECUT2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  721_B cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-ONECUT2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate WB Suggested Anti-ONECUT2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: NCI-H226 cell lysate  ONECUT2 is supported by BioGPS gene expression data to be expressed in NCIH226 100 μL 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-ONECUT2 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Human kidney 100 μL 2 bis 3 Tage
$249.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$507.83
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB   100 μg 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details

Am meisten referenzierte anti-One Cut Homeobox 2 Antikörper

  1. Mouse (Murine) Monoclonal ONECUT2 Primary Antibody für ICC, FACS - ABIN438852 : Dorrell, Erker, Lanxon-Cookson, Abraham, Victoroff, Ro, Canaday, Streeter, Grompe: Surface markers for the murine oval cell response. in Hepatology (Baltimore, Md.) 2008 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Monoclonal ONECUT2 Primary Antibody für ICC, FACS - ABIN438858 : Dorrell, Erker, Schug, Kopp, Canaday, Fox, Smirnova, Duncan, Finegold, Sander, Kaestner, Grompe: Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. in Genes & development 2011 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) Monoclonal ONECUT2 Primary Antibody für FACS, IHC (fro) - ABIN438832 : Lu, Li, Kim, Bossuyt, Liu, Qiu, Wang, Halder, Finegold, Lee, Johnson: Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen One Cut Homeobox 2 Interaktionspartner

Mouse (Murine) One Cut Homeobox 2 (ONECUT2) Interaktionspartner

  1. Onecut1 and Onecut2 have roles in operating downstream of Pax6 to regulate horizontal cell development

  2. similar to Onecut1, Onecut2 is also necessary for the formation of normal numbers of horizontal cells in the developing retina.

  3. identified downstream genes of Oc1 and Oc2 that shows that the onecut factors suppress the production of the late cell type, rods, indicating that the two factors contribute to the competence of retinal progenitor cells for early retinal cell fates

  4. OC-2 is required for development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.

  5. Onecut2 and Onecut1 have similar expression patterns throughout retinal development and may also function in the genesis and maintenance of retinal horizontal cells.

  6. Data show that Onecut-2/Onecut-3 double knockout is a perinatal lethal.

  7. These results indicate that the expression of HNF-6 and OC-2 regulators of liver and pancreas development is modulated by miR-495 and miR-218.

  8. Our data unveil a complex and dynamic expression profile of the OC proteins in spinal MN, which suggests that these factors may participate in regulatory networks that control different steps of motor neuron development.

  9. We describe here the cloning of mouse (m) OC-2 and its expression pattern in the mouse embryo.

  10. although hepatocyte nuclear factor (HNF)6/onecut(OC)-2 and perhaps HNF1 activate the P2 promoter in the embryo, increasing HNF4alpha1 expression throughout development causes a switch to essentially exclusive P1 promoter activity in the adult liver

  11. Onecut transcription factor Onecut2 inhibits activin/TGF beta signaling in the parenchyma, and this allows normal hepatocyte differentiation.

  12. HNF-6 and OC-2 play partially redundant roles in developing pancreas, antero-posterior patterning of the gut and in enteroendocrine differentiation.

  13. Data suggest that the Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration.

Human One Cut Homeobox 2 (ONECUT2) Interaktionspartner

  1. Here we identify the transcription factor ONECUT2 (OC2) as a master regulator of AR networks in metastatic castration-resistant prostate cancer (mCRPC). OC2 acts as a survival factor in mCRPC models, suppresses the AR transcriptional program by direct regulation of AR target genes and the AR licensing factor FOXA1, and activates genes associated with neural differentiation and progression to lethal disease.

  2. ONECUT2 activates SMAD3, which regulates hypoxia signaling through modulating HIF1alpha chromatin-binding, leading neuroendocrine prostate cancers to exhibit higher degrees of hypoxia compared to prostate adenocarcinomas.

  3. These data indicated that OC-2 was an upstream regulator of VEGFA and silencing OC-2 could inhibit ovarian cancer angiogenesis and tumor growth.

  4. Bioinformatics-based prediction, combined with qRT-PCR analysis and Western blotting, identified Onecut2 and SIRT1 as the 2 prominent miR-9 target genes under the conditions tested. In this study, Onecut2 and SIRT1 were confirmed as miR-9 target genes, which will help future investigations to probe in greater detail the role of miR-9 in Nonalcoholic Fatty Liver Disease.

  5. Data show that ONECUT2, IGF2BP1, and ANXA2 proteins were confirmed to be microRNA-9 (miR-9) targets and aberrantly upregulated in hepatocellular carcinoma (HCC).

  6. our data showed that transcript factor Onecut2 is involved in the EMT, migration and invasion of CRC cells; miR-429 inhibits the initiation of EMT and regulated expression of EMT-related markers

  7. Mutations at the -5/-6 site of the F9 promotor account for the majority of hemophilia B Leyden cases and disrupt the binding of ONECUT1 and ONECUT2.

  8. OC2 transcription factor is a direct target of T-bet in type-1 T-helper cells.

  9. A CpG island proximal to ONECUT2 is frequently methylated in diffuse large B-cell lymphoma (DLBCL).

One Cut Homeobox 2 (ONECUT2) Antigen-Profil

Protein Überblick

This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.

Genbezeichner und Symbole assoziert mit ONECUT2

  • one cut domain, family member 2 (Onecut2) Antikörper
  • one cut homeobox 2 (ONECUT2) Antikörper
  • one cut homeobox 2 (Onecut2) Antikörper
  • C730009D12 Antikörper
  • OC-2 Antikörper
  • OC2 Antikörper
  • RGD1564677 Antikörper

Bezeichner auf Proteinebene für ONECUT2

one cut domain family member 2 , one cut homeobox 2 , transcription factor ONECUT-2 , transcription factor ONECUT2 , HNF-6-beta , ONECUT-2 homeodomain transcription factor , hepatocyte nuclear factor 6-beta , one cut domain, family member 2 , onecut 2

GENE ID SPEZIES
225631 Mus musculus
9480 Homo sapiens
483967 Canis lupus familiaris
307376 Rattus norvegicus
Ausgewählte Anbieter für anti-One Cut Homeobox 2 (ONECUT2) Antikörper
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