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NUCB2 encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. Zusätzlich bieten wir Ihnen Nucleobindin 2 Kits (76) und Nucleobindin 2 Proteine (38) und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal NUCB2 Primary Antibody für IHC, WB - ABIN2774832
Linē, Stengrēvics, Slucka, Li, Jankevics, Rees: Serological identification and expression analysis of gastric cancer-associated genes. in British journal of cancer 2002
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Human Polyclonal NUCB2 Primary Antibody für IF (p), IHC (p) - ABIN700690
Jia, Li, Li, Wu, Xie, Lin: Role of nesfatin-1 in a rat model of visceral hypersensitivity. in World journal of gastroenterology : WJG 2013
Human Polyclonal NUCB2 Primary Antibody für ICC, IF - ABIN4338639
Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012
Human Polyclonal NUCB2 Primary Antibody für IAC, IEM - ABIN2452060
Taniguchi, Taniura, Niinobe, Takayama, Tominaga-Yoshino, Ogura, Yoshikawa: The postmitotic growth suppressor necdin interacts with a calcium-binding protein (NEFA) in neuronal cytoplasm. in The Journal of biological chemistry 2000
It is confirmed herein that nesfatin-1 can regulate appetite in the pig and affect the gonadotropic axis of the prepubertal pig
Suggest that catecholaminergic and c-fos immunoreactive NUCB2/nesfatin-1 neurons could contribute in the anorexigenic effects of the mycotoxin deoxynivalenol.
Study demonstrated that high expression level of NUCB2 was significantly associated with poor clinical outcome of patient with non-metastatic clear cell renal cell carcinoma (zeige MOK Antikörper).
The multifunctional biological actions of nesfatin-1 propelled this peptide as a therapeutic target, and as a potential biomarker of diseases. However, a better and comprehensive understanding of tissue specific effects of nesfatin-1 is critical prior to exploring its possible use in the detection and treatment of diseases.
Data indicate that nesfatin-1/NUCB-2 enhanced migration, invasion and epithelial-mesenchymal transition (EMT (zeige ITK Antikörper)) in colon cancer cells through LKB1 (zeige STK11 Antikörper)/AMPK (zeige PRKAA1 Antikörper)/TORC1 (zeige CRTC1 Antikörper)/ZEB1 (zeige ZEB1 Antikörper) pathways in vitro and in vivo.
Nesfatin-1 levels decrease following biliopancreatic diversion with duodenal switch-induced weight loss and are significantly associated with parameters of metabolic health.
women and men showed an inverse association between NUCB2/nesfatin-1 and anxiety with a positive correlation in women and a negative correlation in men. However, no significant change of NUCB2/nesfatin-1 following improvement of anxiety has been observed.
Our study was the first to investigate the nesfatin 1 levels in patients with the first episode psychosis. Based on our study results, nesfatin 1 might be related to some central nervous system pathologies, including the severity of a psychiatric disorder.
nucleobindin 2 might play a crucial role in gastric cancer development and could serve as an independent predictor of prognosis of gastric cancer patients.
Based on the obtained results, it was proposed that ghrelin (zeige GHRL Antikörper) may be considered as playing a role in the etiopathogenesis of hyperemesis gravidarum that may result in disruption of the relationship between nesfatin-1 and ghrelin (zeige GHRL Antikörper).
This study supports the role of insulin (zeige INS Antikörper) resistance in decreased nesfatin-1 levels in patients with Type 2 diabetes mellitus and metabolic syndrome
Increased plasma nesfatin-1 concentrations are associated closely with inflammation, trauma severity and clinical outcomes, indicating that nesfatin-1 might be involved in inflammation and become a good prognostic biomarker following traumatic brain injury
Polymorphism in the exon 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 and 11 of bovine NUCB2 gene was detected in 686 individuals from three Chinese cattle breeds.
Tension receptor mechanosensitivity was unaffected by nesfatin-1 in SLD and fasted mice, but was inhibited in HFD mice. In conclusion, Nesfatin-1 modulates gastric vagal afferent mechanosensitivity in a nutritional state dependent manner.
Nesfatin-1 acts directly on hypothalamic neurons and gonadotropes to elicit a generally positive influence on the endocrine milieu regulating reproduction in mice. Reproductive hormones, in turn, modulate brain and pituitary NUCB2/nesfatin-1.
The results reveal that the endogenous NUCB2/nesfatin-1 in PVN regulates PVN AVP (zeige AVP Antikörper) and oxytocin and consequently the fluid and energy balance.
Study provides evidence for direct regulation of hepatic lipid metabolism by nesfatin-1 through an AMPK (zeige PRKAA1 Antikörper)-dependent mechanism.
reproductive-endocrine regulation through hypothalamus-pituitary-ovary axis may contribute to nesfatin-1/NUCB2 expression in the pituitary gland.
new information on the cell specific localization of NUCB2/nesfatin-1 in the intestinal mucosa, and a novel function for nesfatin-1 in modulating intestinal CCK (zeige CCK Antikörper) and PYY expression and secretion
MGN3-1 cells respond differently to nutrients in secreting NUCB2/nesfatin-1 and ghrelin (zeige GHRL Antikörper). Similarly, acute or chronic intake of nutrients does influence NUCB2 mRNA expression and NUCB2/nesfatin-1 release in a diet specific manner.
Our data suggested that nesfatin-1 exerted its neuroprotective effect on dopaminergic cells against rotenone by ameliorating mitochondrial dysfunction and its anti-apoptotic property.
NUCB2/nesfatin-1 is co-localized with GLP-1 (zeige GCG Antikörper) and GIP (zeige GIP Antikörper) in small intestinal cells. Data support the hypothesis that nesfatin-1 is present in enteroendocrine cells and that it stimulates incretin secretion.
These results indicate that paraventricular nucleus NUCB2/nesfatin-1 is directly targeted by leptin (zeige LEP Antikörper), and mediates its anorexigenic effect.
This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains.
, DNA-binding protein NEFA
, gastric cancer antigen Zg4
, nucleobinding 2