NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Proteine (NDUFV2)

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. Zusätzlich bieten wir Ihnen NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Antikörper (87) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NDUFV2 4729 P19404
NDUFV2 72900 Q9D6J6
NDUFV2 81728 P19234
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Top NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Proteine auf antikoerper-online.de

Showing 10 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human GST tag NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) (AA 35-249), (partial) protein (GST tag) 1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$1,842.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,539.17
Details
Hefe Schimpanse His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,539.17
Details
Hefe Pongo pygmaeus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,539.17
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,539.17
Details

NDUFV2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) Interaktionspartnern

Human NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) Interaktionspartner

  1. haplotype T-C consisting of rs12457810 and rs12964485 in the 5'-upstream region of NDUFV2 may be a protective factor for the development of MDD in Han Chinese

  2. We have identified NDUFV2 mutations in two families with Complex I deficiency, including a novel mutation.

  3. There is no statistical significance between NDUFV2 gene promoter variants and susceptibility to schizophrenia in Han Chinese.

  4. The mitochondrial targeting sequence of NDUFV2 is located at the N-terminus of the precursor protein. Impairment of mitochondrial localization of NDUFV2 as a mechanistic basis for early-onset hypertrophic cardiomyopathy and encephalopathy was established.

  5. Three single nucleotide polymorphisms in the NDUFV2 gene, were studies in bipolar disorder pateints and controls.

  6. Our findings suggest further studies addressing the role of NDUFV2 variation in Parkinson's disease may be warranted.

  7. Sp1 (zeige PSG1 Proteine) was abnormally expressed in schizophrenia and its mRNA alteration pattern paralleled that of NDUFV1 (zeige NDUFV1 Proteine) and NDUFV2 in schizophrenic patients.

  8. Polymorphisms in the promoter region of NDUFV2 are a genetic risk factor for bipolar disorder. The association of the haplotypes -602G> A and -3542G> A polymorphisms with bipolar disorder was seen both in Japanese case-control samples and NIMH trios.

  9. NDUFV2 individual genotypes were not associated with schizophrenia, but the haplotype consisting of the two single nucleotide polymorphisms were significantly associated with schizophrenia.

  10. genetic variants of NDUFV2 may increase risk for bipolar disorder.

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) Interaktionspartner

  1. The results of this study indicated that ndufv2 knockdown influences the actin cytoskeleton and tubulin (zeige TUBB Proteine) stabilization in the leading process of migrating cortical neurons

  2. The authors biochemically separate the NADH dehydrogenase (zeige NDUFA2 Proteine) module from complex I of bovine heart into subunit I, II and III fractions. Subunit II fraction, also known as the NADH dehydrogenase (ubiquinone) flavoprotein 2 protein, has a molecular weight of 24 000 Da and contains an iron-sulfur center.

  3. The authors use green fluorescent-tagged complex I subunits to determine the kinetics of assembly. Tagged human NDUFV2 can replace the endogenous protein in the holo-complex I protein and was also found in complex I subassemblies, suggesting that NDUFV2 may directly incorporate into the holo-enzyme and may also assemble into smaller complexes or in a monomer pool.

  4. The authors provide an overview of the function and assembly of human complex I, also known as NADH dehydrogenase (zeige NDUFA2 Proteine) (ubiquinone) 1 alpha subcomplex. They discuss its role in oxidative phosphorylation and the implications of complex I deficiency in disease.

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) Interaktionspartner

  1. Data show that during NADH-ubiquinone oxidoreductase (Complex (zeige NDUFA2 Proteine) I) catalytic electron transfer from NADH to DBQ, the superoxide generation site was mostly shifted to the SQ.

  2. Data suggest that Q(Nf) plays a role in a "direct" redox-driven proton pump, while Q(Ns) triggers an "indirect" conformation-driven proton pump in NADH-ubiquinone oxidoreductase (complex (zeige NDUFA2 Proteine) I).

  3. The catalytic function of NDH in the mediation of superoxide generation was investigated by EPR (zeige EREG Proteine) spin-trapping.

NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) Protein Überblick

Protein Überblick

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19.

Genbezeichner und Symbole assoziert mit NDUFV2

  • NADH:ubiquinone oxidoreductase core subunit V2 (NDUFV2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (Ndufv2)
  • NADH:ubiquinone oxidoreductase core subunit V2 (Ndufv2)
  • NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (LOC409793)
  • NADH:ubiquinone oxidoreductase core subunit V2 (ndufv2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (LOC657790)
  • NADH dehydrogenase (ndufv2)
  • NADH dehydrogenase [ubiquinone] flavoprotein 2,mitochondrial (NDUFV2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (Ndufv2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (NDUFV2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (ndufv2)
  • 2900010C23Rik Protein
  • CI-24k Protein
  • DDBDRAFT_0189294 Protein
  • DDBDRAFT_0233206 Protein
  • DDB_0189294 Protein
  • DDB_0233206 Protein
  • GB17038 Protein
  • NuoE Protein
  • zgc:73198 Protein

Bezeichner auf Proteinebene für NDUFV2

NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial , NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial , NADH-ubiquinone oxidoreductase 24 kDa subunit , NADH-ubiquinone oxidoreductase flavoprotein 2 , complex I 24kDa subunit , complex I, mitochondrial respitory chain, 24 kD subunit , nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit , 24-kDa subunit of mitochondrial NADH dehydrogenase , NADH dehydrogenase flavoprotein 2 , NADH dehydrogenase subunit II , NADH-ubiquinone reductase 24 kDa mitochondrial , NADH dehydrogenase ubiquinone flavoprotein 2 , GLEAN_03690 , NADH dehydrogenase [ubiquinone] flavoprotein 2,mitochondrial , OXPHOS complex I 24 kDa subunit , NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa , NADH dehydrogenase flavoprotein 2, 24kDa

GENE ID SPEZIES
4729 Homo sapiens
72900 Mus musculus
81728 Rattus norvegicus
282290 Bos taurus
409793 Apis mellifera
426488 Gallus gallus
455295 Pan troglodytes
480204 Canis lupus familiaris
549920 Xenopus (Silurana) tropicalis
657790 Tribolium castaneum
706067 Macaca mulatta
8628028 Dictyostelium discoideum AX4
10865442 Parachlamydia acanthamoebae UV-7
100037991 Sus scrofa
100115243 Nasonia vitripennis
100137466 Papio anubis
393720 Danio rerio
100719197 Cavia porcellus
Ausgewählte Anbieter für NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Proteine (NDUFV2)
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