Myxovirus (Influenza Virus) Resistance 2 (Mouse) (MX2) ELISA Kits

The protein encoded by MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. Zusätzlich bieten wir Ihnen MX2 Antikörper (30) und MX2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus MX2 MX2 17858 Q9WVP9
Anti-Ratte MX2 MX2 286918  
MX2 4600 P20592
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Top MX2 ELISA Kits auf

Showing 2 out of 7 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 7.81 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Rind (Kuh) 7.81 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für MX2 Interaktionspartner

Mouse (Murine) Myxovirus (Influenza Virus) Resistance 2 (Mouse) (MX2) Interaktionspartner

  1. The amino-terminal domain of Mx2/MxB-dependent interaction with the HIV-1 capsid has been characterized.

Human Myxovirus (Influenza Virus) Resistance 2 (Mouse) (MX2) Interaktionspartner

  1. Authors propose a model whereby multiple components of the nuclear import machinery and nuclear pore complex help position MX2 at the nuclear envelope to promote MX2-mediated restriction of HIV-1.

  2. Here, the authors show that HIV-1 capsid can bind multiple nucleoporins that impacts HIV-1 infection in a manner that is strikingly dependent on cell-type, cell-cycle, and cyclophilin A (CypA). They also show that nucleoporins mediate the function of the antiviral protein MX2, and that MX2 can variably inhibit non-viral nuclear localization signal function.

  3. Study identifies MxB as a potent pan-herpesvirus restriction factor which blocks the uncoating of viral DNA from the incoming viral capsid.

  4. These data demonstrate that human MXB but not other human or murine MX proteins inhibit murine cytomegalovirus propagation. Evidently, the viral protein expression was delayed and the viral DNA amount in nucleus was diminished in MXB expressing cells indicating an obstruction of nuclear entry.

  5. Therefore, these results demonstrate the importance of MxB in alpha interferon-mediated inhibition of HIV-1 infection.

  6. The dynamin-like MxB GTPase serves as a broadly acting intracellular restriction factor that controls retrovirus as well as herpesvirus infections.

  7. MxB dimers form higher order oligomers that restrict retroviral replication by binding to the viral capsid. [review]

  8. These experiments suggested that MxB does not contribute to the HIV-1 restriction observed in IFN-alpha-treated human cells.

  9. Together, the data demonstrate that interferon-beta inhibits foamy virus early in infection and that MxB is not a restriction factor of foamy virus.

  10. We propose that lower-order oligomerization of MX2 is sufficient for the effective inhibition of human immunodeficiency virus type 1.

  11. Study analyzed the evolutionary history of MX2 at the inter- and intraspecific level and use this information to identify a haplotype that associates with natural resistance to HIV-1 infection in humans; the ancestral (G) allele of rs2074560 protects from HIV-1 infection with a recessive effect.

  12. The high prevalence of MxB-resistant mutations in the CypA-binding loop indicates the significant selective pressure of MxB on HIV-1 replication in vivo.

  13. MxB inhibits HIV-1 by interfering with minimally two steps of infection, nuclear entry and post-nuclear trafficking and/or integration, without destabilizing the inherent catalytic activity of viral preintegration complexes.

  14. HIV-seronegative women who use Depo-Provera have the highest levels of Mx2 expression, highlighting a possible mechanism for hormonal modulation of HIV resistance.

  15. The amino-terminal domain of Mx2/MxB-dependent interaction with the HIV-1 capsid has been characterized.

  16. MxB oligomerization is important for the ability of MxB to bind to the HIV-1 core proteins.

  17. A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2.

  18. structural analysis of assembly of human anti-HIV dynamin-like protein MxB/Mx2

  19. MxB binding to the HIV-1 capsid.

  20. To identify protein domains of MX2 that specify HIV-1 inhibition.

Cow (Bovine) Myxovirus (Influenza Virus) Resistance 2 (Mouse) (MX2) Interaktionspartner

  1. MX1-a, MX1B and MX2 are affected by the type I IFN pathway during pregnancy and are involved in an immune response to protect the mother and fetus

  2. Data indicate that the expression profiles of ISG15, MX1, MX2, and OAS1 could be a useful diagnostic biomarker of gestation.

Pig (Porcine) Myxovirus (Influenza Virus) Resistance 2 (Mouse) (MX2) Interaktionspartner

  1. A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus.

  2. Expression of Mx protein and interferon-alpha (IFN-alpha) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.

  3. The porcine Mx1 gene and promoter share the major structural and functional characteristics displayed by their homologs described in cattle, mouse, chicken, and man.

  4. The 341-bp MX2 promoter region contained regulatory sequences for ISRE, GC box, Sp1 and AP-1, as well as a TATA box. Nucleotide sequences of the MX2 promoter region revealed four substitutions and one deletion, in which six genotypes were classified.

MX2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.

Genbezeichner und Symbole assoziert mit MX2

  • MX dynamin-like GTPase 2 (Mx2) Antikörper
  • MX dynamin like GTPase 2 (Mx2) Antikörper
  • MX dynamin like GTPase 2 (MX2) Antikörper
  • myxovirus (influenza virus) resistance 2 (mouse) (MX2) Antikörper
  • AI528743 Antikörper
  • Mx-2 Antikörper
  • Mx3 Antikörper
  • MXB Antikörper

Bezeichner auf Proteinebene für MX2

interferon-induced GTP-binding protein Mx2 , myxovirus resistance protein 2 , interferon-induced GTP-binding protein Mx3 , myxovirus (influenza virus) resistance 3 , myxovirus resistance protein 3 , interferon-regulated resistance GTP-binding protein MXB , p78-related protein , second interferon-induced protein p78 , Mx protein , myxovirus (influenza virus) resistance 2 , interferon-inducible protein p78 , GTP-binding protein Mx2 , myxovirus resistance 2

17858 Mus musculus
286918 Rattus norvegicus
4600 Homo sapiens
280873 Bos taurus
396893 Sus scrofa
780441 Ovis aries
403744 Canis lupus familiaris
780935 Macaca mulatta
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