Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) ELISA Kits

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. Zusätzlich bieten wir Ihnen Myosin Heavy Chain 7, Cardiac Muscle, beta Antikörper (69) und Myosin Heavy Chain 7, Cardiac Muscle, beta Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MYH7 4625 P12883
MYH7 29557 P02564
MYH7 140781 Q91Z83
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Top Myosin Heavy Chain 7, Cardiac Muscle, beta ELISA Kits auf antikoerper-online.de

Showing 6 out of 31 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$736.84
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Ratte 52 pg/mL 125.00 pg/mL - 8000 pg/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$800.00
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Maus 12.4 pg/mL 31.25 pg/mL - 2000 pg/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$757.89
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$867.90
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Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
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Hund
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,095.60
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Weitere ELISA Kits für Myosin Heavy Chain 7, Cardiac Muscle, beta Interaktionspartner

Human Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Interaktionspartner

  1. Mutation in MYH7 was identified as Restrictive Cardiomyopathy - causing mutation.

  2. MYH7-V878A and CACNA1C (zeige CACNA1C ELISA Kits)-A1594V mutations were detected in a Chinese Family with Hypertrophic Cardiomyopathy. Among those with only the MYH7-V878A mutation, subject III-7 showed abnormal ECG recordings, asymmetric septal hypertrophy, and myocardial fibrosis, and subjects II-13 and III-15 showed some abnormal repolarization, borderline LV wall thickness, and normal cardiac magnetic resonance (CMR) findings.

  3. Asn391Thr mutation of MYH7 is a malignant mutation for hypertrophic cardiomyopathy and that mutation carriers should get effective treatment to prevent sudden death.

  4. MYBPC3 (zeige MYBPC3 ELISA Kits) mutation carriers had a high frequency of ventricular arrhythmia and syncope. An absence of family history of sudden death (SD) and past history of syncope are useful prognostic factors in patients with hypertrophic cardiomyopathy. MYH7 and MYBPC3 (zeige MYBPC3 ELISA Kits) mutations did not significantly influence prognosis compared to non-carriers. The patients with the MYBPC3 (zeige MYBPC3 ELISA Kits) mutation should be closely followed for the possibility of SD.

  5. Five of the 19 patients (26.3%) had either a pathogenic variant or a likely pathogenic variant in MYBPC3 (zeige MYBPC3 ELISA Kits) (n=1), MYH7 (n=1), RYR2 (zeige RYR2 ELISA Kits) (n=2), or TNNT2 (zeige TNNT2 ELISA Kits) (n=1). All five variants were missense variants that have been reported previously in patients with channelopathies or cardiomyopathies

  6. Double MYH7 CTTNA3 heterozygotes showed a variable clinical expression of arrhythmogenic cardiomyopathy and hypertrophic cardiomyopathy. One carrier of double mutations in CTTNA3 and MYH7 genes did not fulfill the current diagnostic criteria for cardiomyopathy.

  7. Data provide evidence that MYH7 mutations contributed to 24.4% MYBPC3 (zeige MYBPC3 ELISA Kits) mutations of hypertrophic cardiomyopathy (HCM) cases, that MYBPC3 (zeige MYBPC3 ELISA Kits) constitute the preeminent cause of HCM and that both mutations are phenotypically indistinguishable.

  8. Digenic inheritance of two novel variants in TNNT2 (zeige TNNT2 ELISA Kits) and MYH7 is associated with a severe form of dilated cardiomyopathy.

  9. MYH7-V878A is a hot spot among ethnic Han Chinese with a high penetrance.

  10. Unlike previous Hypertrophic cardiomyopathy (HCM)mutations studied at the molecular level using human beta-cardiac myosin, early-onset HCM mutations lead to significantly larger changes in the fundamental biomechanical parameters and show clear hyper-contractility

Cow (Bovine) Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Interaktionspartner

  1. Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules

Pig (Porcine) Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Interaktionspartner

  1. Akirin2 siRNA abolished arginine-induced upregulation of MyHC I.

  2. Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load.

  3. Mutation analysis of MYH7 gene revealed an in-frame insertion within exon 30 of MYH7 which was perfectly associated with the disease phenotype and confirmed the dominant inheritance.

Mouse (Murine) Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Interaktionspartner

  1. These data demonstrate functional cooperation between Sox6 and Nfix in regulating MyHC-I expression during prenatal muscle development.[MyHC-1]

  2. Male/female Myh7 mutant mice display sex dimorphic crossbridge kinetics accompanied by sex- and hypertrophic cardiomyopathy-dependent cardiac remodeling at the morphometric, histological, and cellular level.

  3. The promoter regions of the SERCA (zeige ATP2A3 ELISA Kits)-2A and beta-MHC genes, Atp2a2 (zeige ATP2A2 ELISA Kits) and Myh7, respectively in murine hearts after one or eight weeks of pressure overload induced by transverse aortic constriction, were evaluated.

  4. Foxo1 (zeige FOXO1 ELISA Kits) has important roles in promoting diabetic cardiomyopathy and controls beta-MHC expression in the development of cardiac dysfunction.

  5. Cooperative/allosteric effects on actomyosin crossbridge recruitment dynamics are increased by beta-MHC.

  6. Reexpression of bMHC is associated at the bMHC promoter with increased H3ac but not H3K4me3.

  7. Metabolic and myosin isoform gene expression switch in sepsis-induced myocardial depression is inducible nitric oxide synthase (zeige NOS2 ELISA Kits)-dependent.

  8. residues situated within or close to the actin-binding interface of the myosin head influence actin binding and thereby modulate actin-activated ATPase (zeige DNAH8 ELISA Kits) activity

  9. Simultaneous defects in MHC7 & TnI (zeige TNNI2 ELISA Kits) accelerate onset & progression of familial hypertrophic cardiomyopathy. Compared with single-mutant models, double-mutant mice develop severe disease & premature death, progressing directly to a dilated phenotype.

  10. the functional consequences of the mutation are fundamentally changed depending upon the context of the cardiac MHC isoform.

Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7) Antigen-Profil

Beschreibung des Gens

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Genbezeichner und Symbole assoziert mit MYH7

  • myosin heavy chain 7 (MYH7) Antikörper
  • myosin heavy chain 7 (Myh7) Antikörper
  • myosin, heavy chain 7, cardiac muscle, beta (MYH7) Antikörper
  • myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7) Antikörper
  • AMHC1 Antikörper
  • B-MHC Antikörper
  • beta-MHC Antikörper
  • CMD1S Antikörper
  • CMH1 Antikörper
  • MPD1 Antikörper
  • Myhc-b Antikörper
  • MyHC-I Antikörper
  • Myhcb Antikörper
  • myosin Antikörper
  • myosin-7 Antikörper
  • SPMD Antikörper
  • SPMM Antikörper

Bezeichner auf Proteinebene für MYH7

beta-myosin heavy chain , myHC-beta , myhc-slow , myopathy, distal 1 , myosin heavy chain (AA 1-96) , myosin heavy chain 7 , myosin heavy chain slow isoform , myosin heavy chain, cardiac muscle beta isoform , myosin, heavy polypeptide 7, cardiac muscle, beta , myosin-7 , rhabdomyosarcoma antigen MU-RMS-40.7A , beta myosin heavy chain , myHC-slow , myosin heavy chain polypeptide 7 cardiac muscle fetal , myosin heavy chain, cardiac muscle, fetal , myosin heavy chain, polypeptide 7 , type slow/beta myosin heavy chain , cardiac muscle , chick atrial myosin heavy chain , heavy polypeptide 7 , myosin heavy chain , MYH-beta/slow , cardiac myosin heavy chain beta , beta cardiac myosin heavy chain , myosin 7 , myosin heavy chain slow type 1 (beta cardiac) , beta-myosin-heavy-chain , myosin beta heavy chain

GENE ID SPEZIES
4625 Homo sapiens
29557 Rattus norvegicus
282714 Bos taurus
395350 Gallus gallus
396860 Sus scrofa
140781 Mus musculus
791234 Equus caballus
403807 Canis lupus familiaris
100101566 Oryctolagus cuniculus
100727138 Cavia porcellus
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