Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) ELISA Kits

Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. Zusätzlich bieten wir Ihnen Myosin Heavy Chain 6, Cardiac Muscle, alpha Antikörper (48) und Myosin Heavy Chain 6, Cardiac Muscle, alpha Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MYH6 29556  
MYH6 4624 P13533
MYH6 17888 Q02566
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Top Myosin Heavy Chain 6, Cardiac Muscle, alpha ELISA Kits auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 0.065 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
$736.84
Details
Ratte 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
$800.00
Details
Rind (Kuh)
  96 Tests 15 bis 18 Tage
$707.14
Details
Affe
  96 Tests 15 bis 18 Tage
$707.14
Details
Huhn
  96 Tests 15 bis 18 Tage
$707.14
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Schwein
  96 Tests 15 bis 18 Tage
$707.14
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Kaninchen
  96 Tests 15 bis 18 Tage
$707.14
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Meerschweinchen
  96 Tests 15 bis 18 Tage
$707.14
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Maus
  96 Tests 15 bis 18 Tage
$707.14
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Schaf
  96 Tests 15 bis 18 Tage
$707.14
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Weitere ELISA Kits für Myosin Heavy Chain 6, Cardiac Muscle, alpha Interaktionspartner

Human Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) Interaktionspartner

  1. Case Reports: venosus defect caused directly by MYH6 stop codon mutation.

  2. Three loci with high mutation frequencies, the 138665410 FOXL2 gene variant, the 23862952 MYH6 gene variant, and the 71098693 HYDIN gene variant were found to be significantly associated with sporadic Atrial Septal Defect (P<0.05); variants in FOXL2 and MYH6 were found in patients with isolated, sporadic Atrial Septal Defect (P<5x10-4).

  3. We developed an human cardiac alpha-myosin -induced myocarditis model in human HLA-DR4 transgenic mice that lack all mouse MHCII genes.

  4. The etiology of MYH6-associated HLHS can be informed using iPSCs.

  5. Rare inherited and de novo variants in 2,871 congenital heart disease probands identified GDF1, MYH6, and FLT4 as causative genes.

  6. the P830L and A1004S alphaMHC mutations alter myocyte contractility in completely different ways while at the same preserving peak intracellular calcium

  7. Data show that compound heterozygosity for recessive myosin heavy chain 6 (MYH6) mutations in patients with hypoplastic left heart and reduced systemic right ventricular ejection fraction.

  8. human alpha- and beta-cardiac myosin, as well as the mutants, show opposite mechanical and enzymatic phenotypes with respect to each other.

  9. The novel MYH6 mutation delE933 causes both structural damage of the sarcomere and functional impairments on atrial action propagation.

  10. Data from molecular dynamic/docking simulations suggest that actin-myosin binding free energy accepts contributions from both electrostatic and nonpolar forces; studies compare cardiac alpha-myosin, beta-myosin, and fast skeletal muscle myosin.

  11. R1165C mutation in MYH9 gene is associated with macroscopic hematuria and presenile cataract.

  12. Perturbations in the MYH6 head domain seem to play a major role in the genetic origin of familial Secundum-type atrial septal defects.

  13. the alpha-isoform of myosin heavy chain is the pathogenic autoantigen for CD4+ T cells in myocarditis

  14. the lifetime risk of being diagnosed with sick sinus syndrome is around 6% for non-carriers of c.2161C>T but is approximately 50% for carriers of the c.2161C>T variant

  15. data indicate that functional variants of MYH6 are associated with cardiac malformations in addition to atrial septal defect and provide a novel potential mechanism

  16. The mutations in MYH6 cause when a genetic cause can be identified, which has estimated to occur in 65% of hypertrophic cardiomyopathy.

  17. Our data provide evidence for a novel form of calcium-independent positive inotropy in failing cardiac myocytes by fast alpha-myosin motor protein gene transfer.

  18. results show that PUR proteins are capable of binding to alpha-MHC mRNA and attenuate its translational efficiency; also show robust expression of PUR proteins in failing hearts where alpha-MHC mRNA levels are suppressed

  19. Mutation in myosin heavy chain 6 causes atrial septal defect

  20. Three heterozygous MYH6 missense mutations were identified in dilated cardiomyopathy probands (P830L, A1004S, and E1457K; 4.3% of probands). A Q1065H mutation was detected in 1 of 21 hypertrophic cardiomyopathy probands.

Mouse (Murine) Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) Interaktionspartner

  1. The TgPLN(R9C) mouse strain is, in the best case, a functionally ambiguous phenocopy of the human PLN(R9C) heterozygote, because a similar constellation of genetically programmed events can not occur in a patient

  2. The stress-induced Brg1-G9a/GLP-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.

  3. Taken together, these results highlight both the importance of using alphaMyHC-Cre mice as controls in conditional knockout studies as well as the need for a less cardiotoxic Cre driver for the field.

  4. Data indicate that the cardiac myosin heavy chain alpha isoform (alphaMHC(403)) transgenic model closely recapitulates human disease.

  5. mutant sarcomeres manifest irreversible cardiomyocyte defects that induce LVH.

  6. Transfecting human beta-MHC V606M into the mouse cardiac alpha-MHC gene caused hypertrophic cardiomyopathy without left ventricular hypertrophy, disarray of myofibers, and interstitial fibrosis. Cyclosporine or Arg453Cys or Arg719Trp worsened the phenotype.

  7. Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression.

  8. Results indicate the downstream targets of insulin, cyclin D1, BAD, alpha-MHC, and GATA-4, elucidate a molecular mechanism of insulin in promoting cell proliferation and differentiation.

  9. Transgenic mouse alpha- and beta-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.

  10. Results show that the binding force between selenium and cardiac myosin (CM), which consists of two heavy chains (MHC) and two pairs of light chains: MLC1 and MLC2, was 100 times stronger than that of daunorubicin (DNR) and CM.

  11. hypertrophied myocytes after TAC have alpha-MyHC only. These data challenge the current paradigm of the fetal hypertrophic gene program and identify a new subpopulation of smaller working ventricular myocytes with more myosin.

  12. the alpha-isoform of myosin heavy chain is the pathogenic autoantigen for CD4+ T cells in myocarditis

  13. Silencing of aMHC is associated at its promoter with decreased H3K4me3, but not decreased H3ac.

  14. TCDD represses the expression of the cardiac development-specific Nkx2.5 homeobox transcription factor, of cardiac troponin-T and of alpha- and beta-myosin heavy chains.

  15. These results suggest that the depressed molecular function in cardiac myosin may initiate the events that cause the heart to remodel and become pathologically dilated.

  16. the alphaMHC gene, in addition to encoding a major cardiac contractile protein, regulates cardiac growth and gene expression in response to stress and hormonal signaling through miR-208

  17. residues situated within or close to the actin-binding interface of the myosin head influence actin binding and thereby modulate actin-activated ATPase activity

  18. Development of hypertrophic cardiomyopathy due to alpha-myosin heavy chain mutations may be accelerated by male hormones or the absence of female hormones.

  19. functional consequences of the mutation are fundamentally changed depending upon the context of the cardiac MHC isoform

Zebrafish Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) Interaktionspartner

  1. Data show that an atrium-specific contractility defect due to mutation of the atrial myosin heavy chain has a profound impact on ventricular development.

Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) Antigen-Profil

Beschreibung des Gens

Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.

Genbezeichner und Symbole assoziert mit MYH6

  • myosin heavy chain 6 (Myh6) Antikörper
  • myosin heavy chain 6 (MYH6) Antikörper
  • myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6) Antikörper
  • myosin, heavy chain 6, cardiac muscle, alpha (MYH6) Antikörper
  • myosin-6 (MYH6) Antikörper
  • myosin-6 (LOC101120580) Antikörper
  • myosin, heavy chain 6, cardiac muscle, alpha (myh6) Antikörper
  • A830009F23Rik Antikörper
  • AA517445 Antikörper
  • alpha-MHC Antikörper
  • amhc Antikörper
  • ASD3 Antikörper
  • CMD1EE Antikörper
  • CMH14 Antikörper
  • MYHC Antikörper
  • Myhc-a Antikörper
  • MYHCA Antikörper
  • SSS3 Antikörper

Bezeichner auf Proteinebene für MYH6

myHC-alpha , myosin heavy chain 6 , myosin heavy chain polypeptide 6 cardiac muscle adult , myosin heavy chain, cardiac muscle alpha isoform , myosin heavy chain, polypeptide 6, cardiac muscle, alpha , myosin, heavy polypeptide 6, cardiac muscle, alpha , myosin-6 , myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) , Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha) , alpha cardiac MHC , alpha myosin , cardiac myosin heavy chain alpha isoform , cardiomyopathy, hypertrophic 1 , myosin heavy chain, cardiac muscle, adult , myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) , atrial myosin heavy chain , myosin-7 , wea , weak atrium

GENE ID SPEZIES
29556 Rattus norvegicus
4624 Homo sapiens
17888 Mus musculus
100685644 Canis lupus familiaris
100296004 Bos taurus
100125987 Oryctolagus cuniculus
100727418 Cavia porcellus
101120580 Ovis aries
386711 Danio rerio
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