anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) Antikörper

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. Zusätzlich bieten wir Ihnen MLLT11 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MLLT11 10962 Q13015
MLLT11 56772 P97783
MLLT11 295264 Q5M971
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Top anti-MLLT11 Antikörper auf antikoerper-online.de

Showing 10 out of 33 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of MLLT11 using COLO205 whole cell lysates 100 μL 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged MLLT11 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (35.64 KDa) . 100 μg 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Antigen: 0.2ug/100ul, Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in MicroplateReader by 450nm 100 μL 3 bis 7 Tage
$317.90
Details
Human Kaninchen Unkonjugiert WB Western blot analysis MLLT11 using COLO205 whole cell lysates. 100 μg 11 bis 16 Tage
$454.83
Details
Human Kaninchen Cy5.5 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Cy3 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Cy5 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Cy7 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen HRP IHC (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details

Am meisten referenzierte anti-MLLT11 Antikörper

  1. Human Monoclonal MLLT11 Primary Antibody für ELISA, WB - ABIN564754 : Chang, Li, Hou, Wu, Lu, Di, Jin, Ou, Shen, Shao: Identification of the functional role of AF1Q in the progression of breast cancer. in Breast cancer research and treatment 2008 (PubMed)
    Show all 5 Pubmed References

Weitere Antikörper gegen MLLT11 Interaktionspartner

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) Interaktionspartner

  1. This finding suggested statistically significant role of interaction of TXNIP and AF1q polymorphisms (TXNIP-rs2236566, TXNIP-rs7211, and AF1q-rs2769605) in schizophrenia susceptibility.

  2. AF1q was up-regulated in human colorectal cancer tissues, and that this up-regulation was associated with tumor metastasis. AF1q contributes to CRC tumorigenesis through the activation of the AKT signaling pathway.

  3. Data show that MLLT11/AF1q-induced PDGFR signaling enhanced STAT3 activity through Src kinase activation.

  4. AF1q was significantly lower in borderline ovarian tumors (i.e., tumors of low malignant potential without stromal invasion) than in invasive tumors, thus corroborating the association between high AF1q expression and increased migratory/invasive cell behavior and confirming its potential role in ovarian cancer progression.

  5. These results suggest that AF1q would have a role as an enhancer in generation of stem-like population through activation of Wnt signaling pathway.

  6. Findings indicate that breast cancer cells with a hyperactive AF1q/TCF7/CD44 regulatory axis in the primary sites may represent "metastatic founder cells" which have invasive properties.

  7. Results demonstrate that AF1q gene transcription is regulated by REST through direct binding at -383 to -363 bp of AF1q promoter.

  8. AF1Q had a KFERQ-like motif.

  9. AF1q plays a role in the onset of basal apoptosis in ovarian cancer cells, thus providing new information about the activity of this protein whose biologic functions are mostly unknown

  10. Using in vitro assays based on either forced expression or shRNA-mediated silencing of AF1q, the study provides evidence that the protein promotes T- over B-cell differentiation in multipotent hematopoietic progenitors.

  11. AF1q up-regulation of BAD is through its effect on NF-kappaB and this may hint of its oncogenic mechanism in cancer.

  12. The ectopic expression of human AF1q triggered the expression of the neuronal marker TuJ1 in non-neuronal human embryonic kidney (HEK) cells.

  13. overexpression of AF1Q leads to more progression in human breast cancer

  14. The study provides the first evidence that AF1q plays a critical role in the regulation of apoptosis and drug resistance.

  15. high AF1q expression is a poor prognostic marker for adult patients with normal cytogenetics acute myeloid leukemia

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) Interaktionspartner

  1. aberrant expression of AF1q may activate Wnt/beta-catenin signaling and result in podocyte injury

  2. MLLT11 is a pan-neuronal marker, suggesting a role in neural differentiation in the central nervous system and neural crest-cell derived peripheral ganglia

  3. The mouse Af1q, homologue of human AF1q, was found to be significantly up-regulated during the neuronal production from neural stem cells

MLLT11 Antigen-Profil

Protein Überblick

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1\;11)(q21\;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.

Genbezeichner und Symbole assoziert mit MLLT11

  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11) Antikörper
  • MLLT11, transcription factor 7 cofactor (MLLT11) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (Mllt11) Antikörper
  • MLLT11, transcription factor 7 cofactor (Mllt11) Antikörper
  • MLLT11, transcription factor 7 cofactor (mllt11) Antikörper
  • Af1q Antikörper
  • AI839562 Antikörper
  • fc23g02 Antikörper
  • RGD1305525 Antikörper
  • RP11-316M1.10 Antikörper
  • si:ch211-210h11.4 Antikörper
  • wu:fc23g02 Antikörper
  • Zfp692 Antikörper

Bezeichner auf Proteinebene für MLLT11

protein AF1q , ALL1 fused gene from chromosome 1q , ALL1-fused gene from chromosome 1q , zinc finger protein 692 , AF1Q protein

GENE ID SPEZIES
100520242 Sus scrofa
100682887 Canis lupus familiaris
10962 Homo sapiens
56772 Mus musculus
295264 Rattus norvegicus
539519 Bos taurus
100173899 Pongo abelii
563531 Danio rerio
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