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MUC2 encodes a member of the mucin protein family. Zusätzlich bieten wir Ihnen MUC2 Kits (58) und MUC2 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 237 products:
Human Monoclonal MUC2 Primary Antibody für IHC, ELISA - ABIN966605
Chang, Dohrman, Basbaum, Ho, Tsuda, Toribara, Gum, Kim: Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer. in Gastroenterology 1994
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Human Monoclonal MUC2 Primary Antibody für IHC (f), IHC (fro) - ABIN2689853
Devine, Birrell, Whitehead, Harada, Xing, McKenzie: Expression of MUC1 and MUC2 mucins by human tumor cell lines. in Tumour biology 1993
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Human Monoclonal MUC2 Primary Antibody für FACS, ICC - ABIN4336463
Salerno-Goncalves, Safavie, Fasano, Sztein: Free and complexed-secretory immunoglobulin A triggers distinct intestinal epithelial cell responses. in Clinical and experimental immunology 2016
Human Monoclonal MUC2 Primary Antibody für FACS, IHC (fro) - ABIN265845
Mishra, Verma, Alpini, Meng, Kumar: Role of Janus kinase 3 in mucosal differentiation and predisposition to colitis. in The Journal of biological chemistry 2013
Human Polyclonal MUC2 Primary Antibody für ICC, IF - ABIN441262
Kameoka, Kitazawa, Ariasu, Tachibana, Mizuno, Haraguchi, Kitazawa: Reactivation of CDX2 in Gastric Cancer as Mark for Gene Silencing Memory. in Acta histochemica et cytochemica 2015
Human Monoclonal MUC2 Primary Antibody für IHC (fro), FACS - ABIN2475754
Durrant, Jacobs, Price: Production of monoclonal antibodies recognising the peptide core of MUC2 intestinal mucin. in European journal of cancer (Oxford, England : 1990) 1994
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Human Monoclonal MUC2 Primary Antibody für FACS - ABIN2475755
Paulsen, Corfield, Hinz, Hoffmann, Schaudig, Thale, Berry: Characterization of mucins in human lacrimal sac and nasolacrimal duct. in Investigative ophthalmology & visual science 2003
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The O-glycosyltransferase (zeige OGT Antikörper) abundances along the intestine correlated well with the Muc2 O-glycan patterns. Some of the glycosyltransferases involved in the O-glycan elongation were decreased in GF mice, something that is in concordance with the observed shorter Muc2 O-glycans
The goblet cell-derived RELM-beta (zeige RETNLB Antikörper) drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis.
The major responsible region for MUC2 expression exists in amino acids 1-36 of SAA3.
loss of KLF4 (zeige KLF4 Antikörper) and expression of MUC2 could be important markers for gastric cancer diagnosis.
These studies demonstrate regulatory mechanisms between MUC2 and cathelicidins in the colonic mucosa where an intact mucus barrier is essential for expression and secretion of cathelicidins in response to E. histolytica- and DSS (zeige PMP22 Antikörper)-induced colitis.
the intestinal specificity of mucin 2 (MUC2) expression was identified in mice and humans, and further confirmed in chickens.
This triggers calcium ion-dependent compound exocytosis of Muc2 mucin (zeige SLC13A2 Antikörper) from the senGC and generates an intercellular gap junction signal; in turn, this signal induces Muc2 secretion from adjacent goblet cells in the upper crypt, which expels bacteria.
HIF-1alpha (zeige HIF1A Antikörper) inhibition decreases MUC2 production and mucinous tumor growth, providing a preclinical rationale for the use of HIF-1alpha (zeige HIF1A Antikörper) inhibitors to treat patients with PMP
colitic Muc2-/- mice have reduced colon CD103 (zeige ITGAE Antikörper)+ CD11b (zeige ITGAM Antikörper)- dendritic cells and increased CD103 (zeige ITGAE Antikörper)- CD11b (zeige ITGAM Antikörper)+ phagocytes.
expression of MUC2 mRNA is found to be more expressed in Eimeria infected females than males
Our data demonstrate a critical role of the MLP/MyBP-C (zeige MYBPC3 Antikörper) complex during early myoblast differentiation. Its absence in muscles with mutations or aberrant expression of MLP or MyBP-C (zeige MYBPC3 Antikörper) could be directly implicated in the development of cardiac and skeletal myopathies.
Airway MUC2 levels are decreased in patients with severe chronic obstructive pulmonary disease colonized by potentially pathogenic micro-organisms.
Our association of MUC2 in the Dutch ulcerative colitis population could not be replicated in a German cohort, this might be because our associated SNVs are population specific or because of a lack of power.
Among the mild and moderate/severe intestinal metaplasia of gastric mucosa specimens, the relative expression levels of MUC2, a gastrointestinal differentiation marker, were elevated by approximately 6.2- and 21.4-fold
loss of MUC2 expression proved to be a predictor of adverse outcome, while the gain of aberrant expression of MUC5AC and particularly of MUC6 (zeige MUC6 Antikörper) was associated with favorable outcome in colorectal cancer, notably in intermediate stages II and III
This shows for the first time that transamidation is not only stabilizing the skin and the fibrin clot (zeige TXNDC17 Antikörper), but is also important for the correct intracellular processing of MUC2 to generate protective mucus.
Immunohistochemistry showed a reverse correlation between MUC2 and Notch3 or Jagged1 (P = 0.033 and P = 0.005, respectively) and between MUC5AC and Jagged1 or Hes1
Our results unraveled an important regulatory role for MUC2 mucin (zeige SLC13A2 Antikörper) in human beta-defensin2 mRNA and peptide production in a proinflammatory milieu
identified a specific depletion of secreted MUC2 from goblet cells in Lawsonia intracellularis-infected pigs that correlated with the increased level of intracellular bacteria in crypt cells
The structures of purified soluble porcine gastric (Muc5ac) and duodenal (Muc2) mucin (zeige SLC13A2 Antikörper) solutions at neutral and acidic pH were examined using small-angle X-ray scattering and small-angle neutron scattering experiments
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
, secreted gel-forming mucin
, intestinal mucin-2
, mucin 2, intestinal/tracheal
, mucin-like protein