Microspherule Protein 1 Proteine (MCRS1)

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. Zusätzlich bieten wir Ihnen MCRS1 Antikörper (45) und MCRS1 Kits (15) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MCRS1 51812 Q99L90
Ratte MCRS1 MCRS1 300222  
MCRS1 10445 Q96EZ8
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Top MCRS1 Proteine auf antikoerper-online.de

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

MCRS1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,

Weitere Proteine zu Microspherule Protein 1 (MCRS1) Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Microspherule Protein 1 (MCRS1) Interaktionspartner

  1. Results suggest that dMCRS2 is required for loading of RNAP II complexes on the cyclin (zeige PCNA Proteine) gene promoters.

Human Microspherule Protein 1 (MCRS1) Interaktionspartner

  1. Study shows that MCRS1 binds to cytoplasmic dynein (zeige DYNC1H1 Proteine) and contributes to the establishment of centriolar satellites and ciliogenesis.

  2. MSP58 downregulation suppressed the proliferation and invasion of renal cell carcinoma (zeige MOK Proteine) cells.

  3. MCRS1 is phosphorylated by the Aurora-A kinase (zeige AURKA Proteine) in mitosis on Ser35/36.

  4. RINT-1 (zeige RINT1 Proteine) interacts with MSP58 and UBF (zeige UBTF Proteine) within nucleoli and plays a role in ribosomal gene transcription.

  5. The immunoreactivity score (IRS (zeige IARS Proteine)) of MSP58 increased with tumor grade with grade IV gliomas exhibiting the highest expression and showed a highly significant positive correlation with the Ki-67 (zeige MKI67 Proteine) index (r = 0.65, P < 0.001).

  6. Suggest that MSP58 plays an important role in tumorigenesis and progression and may help predict the prognosis of gastric cancer patients.

  7. MCRS1 overexpression induced non-small cell lung cancer proliferation through the miR (zeige MLXIP Proteine)-155-Rb1 (zeige RB1 Proteine) pathway and DNA copy-number amplification is one of the mechanisms underlying MCRS1 overexpression in non-small cell lung cancer.

  8. MSP58 subnuclear localization is regulated by two nuclear import signals, and proper subcellular localization of MSP58 is critical for its role in transcriptional regulation. A molecular mechanism controls nuclear and nucleolar localization of MSP58.

  9. BAP1 (zeige RNF2 Proteine) loss and MCRS1 down-regulation in renal cell carcinoma (zeige MOK Proteine) are associated with adverse clinicopathological features.

  10. MiR (zeige MLXIP Proteine)-129* down-regulation induced MCRS1 overexpression.

MCRS1 Protein Überblick

Protein Überblick

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity.

Genbezeichner und Symbole assoziert mit MCRS1

  • Reduction in Cnn dots 5 (Rcd5)
  • microspherule protein 1 L homeolog (mcrs1.L)
  • microspherule protein 1 (mcrs1)
  • microspherule protein 1 (MCRS1)
  • microspherule protein 1 (CpipJ_CPIJ004521)
  • microspherule protein 1 (Tsp_07041)
  • microspherule protein 1 (Tsp_07058)
  • microspherule protein 1 (Tsp_06917)
  • microspherule protein 1 (Mcrs1)
  • C78274 Protein
  • CG1135 Protein
  • dMCRS1 Protein
  • dMCRS2 Protein
  • Dmel\\CG1135 Protein
  • ICP22BP Protein
  • INO80Q Protein
  • l(3)r0166 Protein
  • l(3)rG166 Protein
  • MCRS1 Protein
  • mcrs2 Protein
  • MSP58 Protein
  • P78 Protein
  • wu:fj97a11 Protein
  • zgc:66428 Protein
  • zgc:77376 Protein

Bezeichner auf Proteinebene für MCRS1

CG1135-PA , Rcd5-PA , lethal (3) rG166 , reduction in Cnn dots 5 , microspherule protein 1 , microspherule protein 1-like , 58 kDa microspherule protein , nucleolar protein , INO80 complex subunit J , INO80 complex subunit Q , cell cycle-regulated factor (78 kDa) , cell cycle-regulated factor p78

GENE ID SPEZIES
38478 Drosophila melanogaster
380567 Xenopus laevis
406557 Danio rerio
451881 Pan troglodytes
477616 Canis lupus familiaris
549534 Xenopus (Silurana) tropicalis
710919 Macaca mulatta
100022253 Monodelphis domestica
100051964 Equus caballus
100394625 Callithrix jacchus
100471618 Ailuropoda melanoleuca
100561650 Anolis carolinensis
100600396 Nomascus leucogenys
6036210 Culex quinquefasciatus
10903334 Trichinella spiralis
10903352 Trichinella spiralis
10912195 Trichinella spiralis
51812 Mus musculus
300222 Rattus norvegicus
10445 Homo sapiens
514410 Bos taurus
426664 Gallus gallus
100343297 Oryctolagus cuniculus
100724960 Cavia porcellus
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