Metastasis Suppressor 1 Proteine (MTSS1)

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.. Zusätzlich bieten wir Ihnen MTSS1 Antikörper (73) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MTSS1 9788 O43312
MTSS1 211401 Q8R1S4
Ratte MTSS1 MTSS1 362918  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Escherichia coli (E. coli) Human MBP tag,His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage

MTSS1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Metastasis Suppressor 1 (MTSS1) Interaktionspartnern

Human Metastasis Suppressor 1 (MTSS1) Interaktionspartner

  1. Data identify MTSS1 as a new Akt2 (zeige AKT2 Proteine)-regulated gene, and point to suppression of MTSS1 as a key step in the metastasis-promoting effects of Akt2 (zeige AKT2 Proteine) in CRC (zeige CALR Proteine) cells.

  2. Data suggest that overexpression of MAEL (zeige MAEL Proteine), caused by gene amplification and/or decreased miR (zeige MLXIP Proteine)-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1.

  3. Overexpression of MTSS1 in PDAC cell lines leads to a loss of migratory potential in vitro and an increase in overall survival in vivo. Data provide insight into an important role for MTSS1 in suppressing tumor cell invasion and migration driven by the tumor microenvironment.

  4. Overexpression of MTSS1 reduced BUCC cell proliferation, cell-cycle progression and colony formation, but had no influence on BUCC cell apoptosis.

  5. in contrast to MIM, which is a prototype of I-BAR proteins and does not contain an SH3 domain, IRTKS (zeige BAIAP2L1 Proteine) promoted serum-induced cell migration along with enhanced phosphorylation of mitogen activated kinases Erk1/2 and p38 (zeige CRK Proteine)

  6. this study shows a previously unknown property of MIM that establishes the linkage of protein ubiquitylation with Rab (zeige HRB Proteine)-guided trafficking of CXCR4 (zeige CXCR4 Proteine) in endocytic vesicles

  7. MTSS1 suppressed H1299 cell migration and invasion, and its expression level can be used as a new independent factor for determining the prognosis of non-small cell lung cancer.

  8. MTSS1 is a new authentic target of miR (zeige MLXIP Proteine)-96 in prostate carcinoma.

  9. Down-regulation of MTSS1 expression is associated with lymph node metastasis in Pancreatic Cancer.

  10. Low expression of Mtss1 is associated with Chronic myeloid leukemia (zeige BCL11A Proteine).

Mouse (Murine) Metastasis Suppressor 1 (MTSS1) Interaktionspartner

  1. Mtss1 is a key linker between the actin cytoskeleton and the cell membrane, for the development and maintenance of a paradigmatic neuronal circuit, the cerebellar cortex.

  2. Study showed that MTSS1 regulates neurite outgrowth and dendritic arborization in primary neurons in vitro, possibly through a Rac1- and PIP (zeige PIP Proteine)-dependent pathway.

  3. role of MIM in the homeostasis of BM cells, including HSPCs, through modulation of the CXCR4 (zeige CXCR4 Proteine)/SDF-1 (zeige CXCL12 Proteine) axis and interactions of BM leukocytes with their microenvironments.

  4. Identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of dendritic spines. MIM accumulated to future spine initiation sites in a PIP2-dependent manner and deformed the plasma membrane outward into a proto-protrusion via its I-BAR domain.

  5. The data demonstrated for the first time an important role for missing-in-metastasis protein in B-cell development. There was a predisposition of missing-in-metastasis-null mice to develop diffuse large B lymphomas.

  6. MTSS1 might be involved in shaping neuronal membranes in vivo.

  7. endogenous MIM protein regulates globally the cell architecture and endocytosis that ultimately influence a variety of cellular behaviors, including cell polarity, motility, receptor signaling and membrane ruffling

  8. MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

  9. Results suggest that MIM promotes ciliogenesis by antagonizing Src (zeige SRC Proteine)-dependent phosphorylation of Cortactin (zeige CTTN Proteine) and describe a mechanism linking regulation of the actin cytoskeleton with ciliogenesis and Shh (zeige SHH Proteine) signaling during tissue regeneration.

  10. tissue-specific regulator of cytoskeletal dynamics that interacts with ATP-actin monomers through its C-terminal WH2 domain

Xenopus laevis Metastasis Suppressor 1 (MTSS1) Interaktionspartner

  1. morphogenetic pathway involving Daam1 (zeige DAAM1 Proteine) and MIM that transduces non-canonical Wnt (zeige WNT2 Proteine) signaling for the cytoskeletal changes and membrane dynamics required for vertebrate neural tube closure

MTSS1 Protein Überblick

Protein Überblick

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.

Genbezeichner und Symbole assoziert mit MTSS1

  • MTSS1, I-BAR domain containing (MTSS1)
  • transmembrane protein 65 (TMEM65)
  • metastasis suppressor protein 1 (LOC100547471)
  • MTSS1, I-BAR domain containing (mtss1)
  • metastasis suppressor 1 (Mtss1)
  • MTSS1, I-BAR domain containing (Mtss1)
  • metastasis suppressor 1, gene 2 L homeolog (mtss1.2.L)
  • 2310003N14Rik Protein
  • BC024131 Protein
  • D130001D01Rik Protein
  • mim Protein
  • mima Protein
  • mimb Protein
  • mKIAA0429 Protein
  • mtss1 Protein

Bezeichner auf Proteinebene für MTSS1

metastasis suppressor 1 , metastasis suppressor protein 1 , metastasis suppressor protein 1-like , metastasis suppressor YGL-1 , missing in metastasis protein , actin monomer-binding protein

711465 Macaca mulatta
100080535 Ornithorhynchus anatinus
100157797 Sus scrofa
100174755 Pongo abelii
100355361 Oryctolagus cuniculus
100410891 Callithrix jacchus
100467780 Ailuropoda melanoleuca
100547471 Meleagris gallopavo
100559325 Anolis carolinensis
100582996 Nomascus leucogenys
464381 Pan troglodytes
9788 Homo sapiens
482037 Canis lupus familiaris
100067482 Equus caballus
523498 Bos taurus
211401 Mus musculus
362918 Rattus norvegicus
420336 Gallus gallus
447209 Xenopus laevis
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