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MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Zusätzlich bieten wir Ihnen MACC1 Kits (11) und MACC1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 43 products:
Human Polyclonal MACC1 Primary Antibody für IF (p), IHC (p) - ABIN706526
Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015
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Human Polyclonal MACC1 Primary Antibody für IHC, IHC (p) - ABIN4332277
Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. in International journal of clinical and experimental medicine 2015
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Human Polyclonal MACC1 Primary Antibody für IHC, IHC (p) - ABIN4332275
Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. in Neuro-oncology 2013
Human Polyclonal MACC1 Primary Antibody für ELISA, IHC - ABIN5582886
Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway. in Journal of hematology & oncology 2016
MACC1 expression stratifies colon cancer patients with unfavorable pMMR status. Stage II colon cancer patients with pMMR/MACC1-low tumors have a similar favorable prognosis to those with dMMR with potential implications for the role of adjuvant therapy
coexistence of high MACC1 and low NM23-H1 (zeige NME1 Antikörper) expression and tumor budding was associated with short overall survival
YB-1 promoted lung adenocarcinoma growth and progression in vitro and in vivo through directly binding to the MACC1 promoter and enhancing MACC1/c-Met pathway.
Serum metastasis-associated in colon cancer-1 (MACC1) levels were higher in breast cancer patients than patients with benign disease or healthy volunteers.
restoration of MACC1 expression could abrogate the anti-metastatic effects of miR (zeige MLXIP Antikörper)-944 on colorectal cancer (CRC (zeige CALR Antikörper))cells with enhanced cell migration and invasion. MACC1/Met/AKT (zeige AKT1 Antikörper) signaling may be implicated with the function of miR (zeige MLXIP Antikörper)-944 in CRC (zeige CALR Antikörper) cells. Altogether, miR (zeige MLXIP Antikörper)-944 potentially act as a prognostic predictor and a drug-target for CRC (zeige CALR Antikörper) patients.
Data suggest that the miR (zeige MLXIP Antikörper)-497/MACC1 axis mediated the effect of XIST on GC cell growth.
these findings highlight the pivotal role of miR (zeige MLXIP Antikörper)-218 in various aspects of MACC1 expression regulation and MACC1-mediated colorectal cancer progression
MACC1-induced tumor progression in colorectal cancer acts, at least in part, via the newly discovered MACC1/Nanog (zeige NANOG Antikörper)/Oct4 (zeige POU5F1 Antikörper) axis.
Data indicate that OR3A4 upregulation contributes to metastasis and tumorigenesis in gastric cancer by regulating the activation of PDLIM2 (zeige PDLIM2 Antikörper), MACC1, NTN4, and GNB2L1 (zeige GNB2L1 Antikörper).
H19 may regulate non-small cell lung cancer (NSCLC) metastasis through modulating cellular signaling pathway proteins related to cell proliferation and cell adhesion, including MACC1, EGFR, beta-catenin and ERK1/2.
Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.
HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer
MACC1 has a role in colorectal cancer and can be used for imaging in xenografts
MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009
SH3 domain-containing protein 7a5
, metastasis-associated in colon cancer protein 1
, putative binding protein 7a5