anti-Matrix Metallopeptidase 28 (MMP28) Antikörper

Human Matrix Metallopeptidase 28 (MMP28) Interaktionspartner

1. Circulating MMP-28 was elevated in atrial fibrillation

2. Results suggest a crucial role of MMP9 at the early stage of carcinogenesis in the large intestine. The increase in MMP9 and TIMP1 mRNA concentration and the decrease in MMP28 in the large intestinal tissue may be a confirmation of cancer.

3. These results proved for the first time that epilysin expression was significantly elevated in glioblastoma

4. A decreased level of IL-33 and an elevated concentration of MMP-28 were found in coronary heart disease patients and correlated with disease severity.

5. MMP28 mRNA expression is highest in healthy tissues when compared to diseased periodontal tissues.

6. Data established a seven-gene (AR, ESR2, GATA3, GBX2, KRT16, MMP28 and WNT11) prognostic signature to define a subset of triple-negative breast cancer (TNBC).

7. Inhibition of BCMO1 expression is associated with increased invasiveness of colon cancer cells and increased expression of MMP7 and MMP28. beta-Carotene can upregulate BCMO1 and reverse these effects.

8. Over-expression of MMP28 provides protection against apoptosis induced by either serum-deprivation or treatment with a protein kinase inhibitor.

9. Gene expression of MMP28 in the intervertebral disk is not regulated by inflammatory mechanisms, is donor-dependent and cannot be positively or negatively linked to the grade of degeneration and only weakly to the occurrence of trauma.

10. basal expression of MMP-2, MMP-9, MMP-28, and Filaggrin was evaluated in oral keratinocytes to collect information about ability of cigarette smoke to modify basal expression pattern of these key enzymes in the absence of clinical signs in oral epithelium

11. MMP28 is frequently overexpressed during progression of gastric carcinoma, and contributes to tumor cell invasion and metastasis.

12. Findings presented here show the first documentation of intervertebral disc expression and production of MMP28

13. MMP28 gene expression is regulated by Sp1 transcription factor acetylation.

14. Expression of MMP-21 and MMP-28 seems to associate with the Merkel cell carcinoma of lesser malignant potential.

15. Epilysin (MMP-28) expression is associated with cell proliferation during epithelial repair.

16. Results suggest inhibition of MMP-28 may be beneficial under conditions of dysmyelination.

17. Data demonstrate that expression of MMP28 alters keratinocyte phenotype towards a more adhesive, less migratory behaviour.

18. Epilysin (MMP-28) is deposited to the basolateral extracellular matrix of epithelial cells.

Mouse (Murine) Matrix Metallopeptidase 28 (MMP28) Interaktionspartner

1. results demonstrate that Ranbp2 controls nucleocytoplasmic, chemokine and metalloproteinase 28 signaling, and proteostasis of substrates that are crucial to motoneuronal homeostasis and whose impairments by loss of Ranbp2 drive ALS-like syndromes

2. MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis.

3. MMP-28 deletion aggravated MI-induced LV dysfunction and rupture as a result of defective inflammatory response and scar formation by suppressing M2 macrophage activation.

4. Epilysin is alternatively spliced and processed by a furin-like proprotein convertase.

5. These results suggest that MMP-28 plays an evolutionarily conserved role in neural development and is likely to modulate the axonal-glial extracellular microenvironment.

6. Epilysin serves as a negative regulator of early macrophage recruitment, a novel function that may have evolved as a mechanism to restrain unnecessary and untimely inflammation.