Matrix Metallopeptidase 24 (Membrane-inserted) Proteine (MMP24)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen Matrix Metallopeptidase 24 (Membrane-inserted) Antikörper (69) und Matrix Metallopeptidase 24 (Membrane-inserted) Kits (29) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MMP24 10893 Q9Y5R2
MMP24 17391 Q9R0S2
MMP24 83513 Q99PW6
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Showing 8 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag 10 μg Anmelden zum Anzeigen 6 bis 7 Tage
$482.80
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$749.00
Details
Escherichia coli (E. coli) Human His tag   200 μg Anmelden zum Anzeigen 6 bis 7 Tage
$7,060.80
Details
Escherichia coli (E. coli) Human His tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$613.33
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human MMP24 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$668.03
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,523.67
Details

MMP24 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,
Rat (Rattus)

Weitere Proteine zu Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) Interaktionspartnern

Human Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) Interaktionspartner

  1. MMP24 overexpression is associated with lung cancer metastasis.

  2. Polymorphisms in MAP3K3 (zeige MAP3K3 Proteine), MMP24 and IGF1R (zeige IGF1R Proteine) are associated with greater height and act additively on height in children of an admixed population.

  3. In absolute mRNA levels, significant differences were found in expression of MMP2, MMP24, and MMP25 in gastric carcinoma compared with superficial gastritis.

  4. MMP-24 gene silencing by RNAi can suppress the invasiveness of ovarian cancer SKOV(3) cells in vitro.

  5. MT5-MMP retrieval to the plasma membrane is regulated by Mint-3 (zeige APBA3 Proteine) by binding to its carboxyl end motif EWV

  6. MT5-MMP is expressed in normal human endometrium and there is enhanced exprestion in endometrium from patients with entometriosis with strongest signal in epithelial cells.

  7. These results suggest more than one human MT5-MMP transcript may exist in the central nervous system.

Mouse (Murine) Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) Interaktionspartner

  1. MT5-MMP emerges as a new pro-amyloidogenic regulator of APP (zeige APP Proteine) metabolism, whose deficiency alleviates amyloid pathology, neuroinflammation and cognitive decline.

  2. APP (zeige APP Proteine) carboxy-terminal fragment generation is mediated in part by membrane-bound matrix metalloproteinases such as MT5-MMP, referred to as eta-secretase activity

  3. identify MT5-MMP as a membrane-type metalloproteinase responsible for the shedding of the N-cadherin (zeige CDH2 Proteine) ectodomain in this niche

  4. MT5-MMP-deficient mice did not develop neuropathic pain with mechanical allodynia after sciatic nerve injury.

  5. MT5-MMP retrieval to the plasma membrane is regulated by Mint-3 (zeige APBA3 Proteine) by binding to its carboxyl end motif EWV

  6. These results suggest that ABP directs MT5-MMP proteolytic activity to growth cones and synaptic sites in neurons, where it may regulate axon pathfinding or synapse remodeling through proteolysis of cadherins or other ECM (zeige MMRN1 Proteine) or cell adhesion molecules.

  7. Findings demonstrate an essential role of MT5-MMP in the development of dermal neuro-immune synapses and suggest that this metalloproteinase may be a target for pain control.

Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) Protein Überblick

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily\; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24.

Genbezeichner und Symbole assoziert mit MMP24

  • matrix metallopeptidase 24 (MMP24)
  • matrix metallopeptidase 24 (Mmp24)
  • matrix metallopeptidase 24 (mmp24)
  • AU040325 Protein
  • MMP-24 Protein
  • MMP25 Protein
  • MT-MMP 5 Protein
  • MT-MMP5 Protein
  • Mt5-mmp Protein
  • MT5MMP Protein
  • MTMMP5 Protein
  • si:ch211-239j9.5 Protein

Bezeichner auf Proteinebene für MMP24

matrix metalloproteinase 24 (membrane-inserted) , matrix metalloproteinase-24 , membrane-type 5 matrix metalloproteinase , membrane-type matrix metalloproteinase 5 , membrane-type-5 matrix metalloproteinase , MMP-21 , MMP-24 , MT-MMP 5 , matrix metalloproteinase 24 , matrix metalloproteinase-21 , membrane type 5-MMP

GENE ID SPEZIES
10893 Homo sapiens
17391 Mus musculus
83513 Rattus norvegicus
571143 Danio rerio
419141 Gallus gallus
100731826 Cavia porcellus
100627204 Sus scrofa
100101607 Oryctolagus cuniculus
536622 Bos taurus
100069462 Equus caballus
101119580 Ovis aries musimon
485849 Canis lupus familiaris
Ausgewählte Anbieter für Matrix Metallopeptidase 24 (Membrane-inserted) Proteine (MMP24)
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