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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP1 Kits (135) und MMP1 Proteine (54) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 346 products:
Human Polyclonal MMP1 Primary Antibody für WB - ABIN3043405
Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011
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Mouse (Murine) Polyclonal MMP1 Primary Antibody für IF (p), IHC (p) - ABIN668931
Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014
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Human Polyclonal MMP1 Primary Antibody für ELISA, IHC - ABIN4334917
Huu, Matsushita, Jin, Hamaguchi, Hasegawa, Takehara, Fujimoto: FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin. in Arthritis and rheumatism 2013
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Human Monoclonal MMP1 Primary Antibody für ICC, FACS - ABIN969287
Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010
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Human Polyclonal MMP1 Primary Antibody für IF (p), IHC (p) - ABIN668466
Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012
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Human Monoclonal MMP1 Primary Antibody für FACS, IF - ABIN966588
Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009
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Human Polyclonal MMP1 Primary Antibody für IHC (p), IP - ABIN948134
Kim, Xuan, Park: Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts. in International journal of cosmetic science 2016
Human Monoclonal MMP1 Primary Antibody für IHC (p), WB - ABIN2475718
Murray, Duncan, Arbuckle, Melvin, Fothergill: Matrix metalloproteinases and their inhibitors in gastric cancer. in Gut 1999
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Human Polyclonal MMP1 Primary Antibody für WB - ABIN517953
Teng, Wang, Hood, Conrads, Hamilton, Maxwell, Darcy, Conrads: Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes. in British journal of cancer 2014
Human Monoclonal MMP1 Primary Antibody für FACS - ABIN4896251
Domeij, Modéer, Quezada, Yucel-Lindberg: Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. in Biochemical and biophysical research communications 2005
The current study indicated that MMP1 has a key role in the regulation of cervical tumor growth and lymph node metastasis via epithelial mesenchymal transition to a certain extent
2G allele of MMP-1, C allele of MMP-2 (zeige MMP2 Antikörper) and 5A/6A genotype of MMP-3 (zeige MMP3 Antikörper) are associated with susceptibility and disease progression of type 2 diabetic nephropathy
this study provides insights into the development of a possible alternative therapy manipulating MMP-1 and the mTOR (zeige FRAP1 Antikörper) signaling pathway in Epidermal growth factor receptor (zeige EGFR Antikörper)-tyrosine kinase (zeige RET Antikörper) inhibitor-resistant lung adenocarcinoma.
Specific silencing that targeted AMPK (zeige PRKAA1 Antikörper) resulted in the enhancement of mobility and contractility and in the production of MMP-1 and MMP-2 (zeige MMP2 Antikörper).
MMP-1 genotype may accelerate the development of HIV-associated neurocognitive disorder (HAND) whereas MMP3 (zeige MMP3 Antikörper) -1612 5A5A genotype may reduce the risk of pathogenesis of HAND.
Authors observed a significant increase in the immunoexpression of collagen I and III in patients with DCM and a significant reduction in the immunoexpression of MMP-1 compared with the control group. Also, the collagen I and TIMP-1 (zeige TIMP1 Antikörper) expression indicated a positive linear correlation and respectively a negative linear relationship with collagen III and MMP-1.
findings suggest that the polymorphic genotypes at MMP-1 promoter -1607 may play a major role in determining personal cancer susceptibility for prostate cancer in Taiwan
No significant association was found between MMP-1 (-16071G/2G, -519A/G) variants and obesity.
Reduced expression of types I and III collagen and TIMP-1 (zeige TIMP1 Antikörper) as well as the increased expression of MMP-1 and MMP-8 (zeige MMP8 Antikörper) in the anterior vaginal wall tissues play important roles in the onset of pelvic organ prolapse.
The results of the present study suggested that miR93 regulated MMP1 and collagen I expression in fibroblasts via calpain2. miR93 mediated collagen expression in stress urinary incontinence via calpain2.
the identification of MMP1 and MMP10 (zeige MMP10 Antikörper) genes in swine is reported.
increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c (zeige PKC Antikörper) pathway and may be due to enhanced phosphorylation of mmp1
Results indicate that leukemia inhibitory factor (LIF (zeige LIF Antikörper)) and Oncostatin M (zeige OSM Antikörper) increase the expression of MMP-1, MMP-3 (zeige MMP3 Antikörper), and TIMP-1 (zeige TIMP1 Antikörper) several fold, and that their expression is reduced to basal levels in the presence of the LIF (zeige LIF Antikörper) antagonist MH35-BD.
results suggest that Ubx regulates organ shape by controlling Mmp1 expression, and the extent and timing of extracellular matrix degradation.
This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.
Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.
Data indicate that matrix metalloproteinases mmp1 and mmp2 (zeige MMP2 Antikörper) mutants have distinct heart phenotypes.
These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.
A primary function of Mmp1, under the control of the JNK (zeige MAPK8 Antikörper) pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.
Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut (zeige GUSB Antikörper) homeostasis
Study identified three genes, regeneration (rgn (zeige RGN Antikörper)), augmenter of liver regeneration (alr (zeige GFER Antikörper)) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.
Infection with Mycobacterium bovis results in increase in interleukin-1alpha, TGF-beta1 (zeige TGFB1 Antikörper), and MMP1 in multinucleated macrophages.
MMP-2 (zeige MMP2 Antikörper) promoted and MMP-13 (zeige MMP13 Antikörper) disrupted vasculogenic mimicry formation in large cell lung cancer by cleaving laminin-5 to influence EGFR (zeige EGFR Antikörper) signal activation.
The data demonstrate that MMP13 (zeige MMP13 Antikörper) and CTGF (zeige CTGF Antikörper) play a crucial role in modulation of fibrogenic mediators while promoting hepatic fibrogenesis.
CXCL10 (zeige CXCL10 Antikörper) has strong inhibitory effects on neovascularization, whereas MMP13 (zeige MMP13 Antikörper) is required for neovascularization in C. albicans-infected corneas.
that MMP-13 (zeige MMP13 Antikörper) is a central protease in infarct development and cortical remodeling during post-stroke neurorepair
the phenotype seen in the Hdac4 (zeige HDAC5 Antikörper)(-/-) mice is partially derived from elevation in MMP-13 (zeige MMP13 Antikörper) and may be due to a bone remodeling disorder caused by overexpression of this enzyme.
MEF2C (zeige MEF2C Antikörper) is necessary for Mmp13 (zeige MMP13 Antikörper) gene expression at the transcriptional level and participates in PTH (zeige PTH Antikörper)-stimulated Mmp13 (zeige MMP13 Antikörper) gene expression by increased binding to c-FOS at the AP-1 (zeige JUN Antikörper) site in the Mmp13 (zeige MMP13 Antikörper) promoter.
data reveal a novel involvement of MMP-13 (zeige MMP13 Antikörper) in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (zeige CCL1 Antikörper) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (zeige CD8A Antikörper)(+) T-cell response in vitro; MMP-13 (zeige MMP13 Antikörper) might be a promising target for therapeutic intervention in inflammatory diseases
The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (zeige DDR2 Antikörper)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (zeige DDR2 Antikörper) and matrix metalloproteinase 13 (zeige MMP13 Antikörper).
Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Antikörper) with an inducible Col2a1 (zeige COL2A1 Antikörper)-Cre caused premature production of pErk1/2 and Mmp13 (zeige MMP13 Antikörper) in the growth plate.
BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA (zeige RBM9 Antikörper), leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.
The expression patterns of MMP1, MMP2 (zeige MMP2 Antikörper), and MMP8 (zeige MMP8 Antikörper) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2 (zeige MMP2 Antikörper), and MMP8 (zeige MMP8 Antikörper) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2 (zeige MMP2 Antikörper), and MMP8 (zeige MMP8 Antikörper) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.
Data suggest that luteolytic factors (such as interferon gamma (zeige IFNG Antikörper), tumor necrosis factor alpha (zeige TNF Antikörper), and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
The results showed that a decrease in MMP-1 and MMP-2 (zeige MMP2 Antikörper) gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.
Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.
MMP-1 promotes VEGFR2 (zeige KDR Antikörper) expression and proliferation of endothelial cells through stimulation of PAR-1 (zeige F2R Antikörper) and activation of NF-kappaB (zeige NFKB1 Antikörper)
These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.
the differential expression and localization of membrane-type 1 matrix metalloproteinase (zeige MMP14 Antikörper) in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2 (zeige MMP2 Antikörper)
increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (zeige MMP13 Antikörper) (follicular apex (zeige APEX1 Antikörper) vs. base) for the preovulatory collagenolysis required for follicle rupture
identification of MT1-MMP (zeige MMP14 Antikörper) in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface
These results suggest that PEP-1-SIRT2 (zeige SIRT2 Antikörper) promotes matrix metalloproteinases-induced dedifferentiation via ERK (zeige MAPK1 Antikörper) signaling in articular chondrocytes. .
Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 (zeige TIMP3 Antikörper) secretion.
ANXA2 (zeige ANXA2 Antikörper) and MMP1 might participate in remodeling during wound healing in the horse.
The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.
These results suggest that MMP-1 and IL-8 (zeige IL8 Antikörper) are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
, interstitial collagenase
, matrix metalloprotease 1
, matrix metalloproteinase 1
, matrix metalloproteinase 1 (type I collagenase)
, matrix metalloproteinase-1
, collagenase 3
, matrix metalloproteinase 13
, matrix metalloproteinase-13
, matrix metalloproteinase-18
, matrix metallopeptidase 1a
, matrix metalloproteinase 1a (interstitial collagenase)
, myocardial collagenase