Matrilin 3 (MATN3) ELISA Kits

MATN3 encodes a member of von Willebrand factor A domain containing protein family. Zusätzlich bieten wir Ihnen Matrilin 3 Antikörper (56) und Matrilin 3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MATN3 4148 O15232
Anti-Maus MATN3 MATN3 17182 O35701
Anti-Ratte MATN3 MATN3 313954  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human
  96 Tests Anmelden zum Anzeigen 21 bis 31 Tage
$541.20
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Weitere ELISA Kits für Matrilin 3 Interaktionspartner

Human Matrilin 3 (MATN3) Interaktionspartner

  1. our results revealed miR (zeige MLXIP ELISA Kits)-483-5p directly targeted to the cartilage matrix protein (zeige MATN1 ELISA Kits) matrilin 3 (Matn3) and tissue inhibitor of metalloproteinase 2 (Timp2 (zeige TIMP2 ELISA Kits)) to stimulate chondrocyte hypertrophy, extracellular matrix degradation, and cartilage angiogenesis, and it consequently initiated and accelerated the development of OA.

  2. The results of the study indicate a potential role for the MATN3 rs28598872 polymorphism in the pathogenesis of Temporomandibular Joint Internal Derangement.

  3. This report is the first to show the involvement of MATN3 in C-type natriuretic peptide/natriuretic peptide receptor-B signaling pathway during the process of transforming growth factor-beta induced chondrogenic differentiation of mesenchymal stem cells.

  4. MATN3 plays a regulatory role in cartilage homeostasis due to its capacity to induce IL-1Ra (zeige IL1RN ELISA Kits), upregulate gene expression of major cartilage matrix components, and downregulate the expression of OA-associated matrix-degrading proteinases in chondrocytes.

  5. MATN3 may have the inherent ability to inhibit premature chondrocyte hypertrophy by suppressing BMP-2 (zeige BMP2 ELISA Kits)/Smad1 (zeige GARS ELISA Kits) activity

  6. The VWA1 (zeige VWA1 ELISA Kits) domain of matrilin-3 is primarily responsible for the induction of IL-6 (zeige IL6 ELISA Kits) release from primary human chondrocytes.

  7. Polymorphism in the MATN3 gene might play a role in osteoarthritis in the Chinese Han population.

  8. Haplotype-4 of MATN3 is associated with vertebral fracture risk independent of bone mineral density in Chinese postmenopausal women.

  9. MATN3 mutations were identified in 13 multiple epiphyseal dysplasia patients and comprised predominantly of missense mutations.

  10. Radiographic findings in patients with COMP (zeige COMP ELISA Kits) and MATN3 mutations showed marked abnormalities in hip and knee joints.

Mouse (Murine) Matrilin 3 (MATN3) Interaktionspartner

  1. Data show that hand osteoarthritis (HOA)-related matrilin-3 mutation (T298M) leads to a high expression level of growth arrest DNA damage-inducible gene 153 (GADD153 (zeige DDIT3 ELISA Kits))

  2. MATN3 plays a regulatory role in cartilage homeostasis due to its capacity to induce IL-1Ra (zeige IL1RN ELISA Kits), upregulate gene expression of major cartilage matrix components, and downregulate the expression of OA-associated matrix-degrading proteinases in chondrocytes.

  3. MATN3 may have the inherent ability to inhibit premature chondrocyte hypertrophy by suppressing BMP-2 (zeige BMP2 ELISA Kits)/Smad1 (zeige SMAD1 ELISA Kits) activity

  4. study will facilitate better awareness of the differential diagnoses that might be associated with the PSACH (zeige COMP ELISA Kits)/MED spectrum and subsequent care of PSACH (zeige COMP ELISA Kits)/MED patients

  5. Lack of COMP (zeige COMP ELISA Kits) and matrilin 3 leads to increased deposition of TIMP-3 (zeige TIMP3 ELISA Kits), which causes partial inactivation of matrix metalloproteinases in bone, including MMP-13 (zeige MMP13 ELISA Kits).

  6. Secretion of matrilin 3 V194D mutant protein is not dependent on hetero-oligomerization with matrilin 1 (zeige MATN1 ELISA Kits).

  7. matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen (zeige COL2A1 ELISA Kits) fibrils

  8. potential of matrilin-3 to modulate gene expression profile of primary chondrocytes; tested matrilin3-dependent induction of pro-inflammatory cytokines, inducible nitric oxide synthetase & cyclooxygenase-2 (zeige PTGS2 ELISA Kits), MMP1 (zeige MMP1 ELISA Kits), -3 & -13, & matrilin-3 itself

  9. Expression of matrilin-3 during maturation of mouse skeletal tissues

  10. To assess the function of matrilin-3 during skeletal development, we have generated Matn-3 null mice; phenotypes of multiple epiphyseal dysplasia disorders are not caused by the absence of matrilin-3 in cartilage ECM (zeige MMRN1 ELISA Kits).

Cow (Bovine) Matrilin 3 (MATN3) Interaktionspartner

Matrilin 3 (MATN3) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains\; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.

Genbezeichner und Symbole assoziert mit Matrilin 3 (MATN3) ELISA Kits

  • matrilin 3 (MATN3) Antikörper
  • matrilin 3 (Matn3) Antikörper
  • AV009181 Antikörper
  • DIPOA Antikörper
  • EDM5 Antikörper
  • HOA Antikörper
  • OADIP Antikörper
  • OS2 Antikörper

Bezeichner auf Proteinebene für Matrilin 3 (MATN3) ELISA Kits

matrilin 3 , matrilin-3-like , matrilin-3

GENE ID SPEZIES
459514 Pan troglodytes
482985 Canis lupus familiaris
716677 Macaca mulatta
100071902 Equus caballus
100221699 Taeniopygia guttata
100392004 Callithrix jacchus
100470832 Ailuropoda melanoleuca
100603025 Nomascus leucogenys
4148 Homo sapiens
17182 Mus musculus
313954 Rattus norvegicus
395954 Gallus gallus
540041 Bos taurus
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