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M6PR encodes a member of the P-type lectin family. Zusätzlich bieten wir Ihnen M6PR Antikörper (71) und M6PR Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.
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Analysis of full-length sequences for MPR 46 from zebrafish (Danio rerio) and its functional analysis.
Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.
After 6 weeks of environmental tobacco smoke exposure, the Sirt-1 (zeige SIRT1 ELISA Kits) protein level was decreased and cardiac autophagy was increased in C57BL mice. Furthermore, the IGF2R (zeige IGF2R ELISA Kits) cardiac hypertrophy signaling pathway was also triggered, although cardiac apoptosis and hypertrophy were not induced.
Finally, Chlamydia trachomatis infection interferes with the SNX5:cation-independent mannose-6-phosphate receptor interaction, suggesting that Chlamydia IncE and cation-independent mannose-6-phosphate receptor are dependent on the same binding surface on SNX5.
Selective M6PR down-regulation has a critical role in CD8 (zeige CD8A ELISA Kits)(+) T cell survival.
Expression of imprinted gene Igf2r (zeige IGF2R ELISA Kits) was unregulated in haploid androgenetic/gynogenetic blastocysts.
that an elevation in IGF-II receptor (zeige IGF2R ELISA Kits) levels can influence the expression profiles of transcripts as well as proteins that are involved in AD pathogenesis.
DNA methylation changes were noted in the Igf2r (zeige IGF2R ELISA Kits) gene during chronic cystitis in a murine model.
Airn expression is both necessary and sufficient to silence Igf2r (zeige IGF2R ELISA Kits) throughout embryonic stem cell differentiation.
We conclude that M6PR is an important receptor used by HIV-1 to cross the blood-brain barrier.
The results excluded a role for spliced and unspliced Airn lncRNA products and for Airn nuclear size and location in silencing Igf2r. Instead, silencing only required Airn transcriptional overlap of the Igf2r promoter, which interferes with RNA polymerase II recruitment in the absence of repressive chromatin.
mannose 6-phosphate/IGF2R knock-down in receptor-positive mouse hepatocytes causes increased cathepsin secretion as well as enhanced cell motility and invasiveness
In light of existing report suggesting critical role of Nef-GCC185 interaction reveals valuable mechanistic insights affecting specific protein transport pathway in docking of late endosome derived Rab9 bearing transport vesicle at TGN (zeige TG ELISA Kits) elucidating role of Nef during viral pathogenesis.
Results suggest that Rab protein Rab29 is essential for the integrity of the trans-Golgi network (TGN (zeige TG ELISA Kits)) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR).
These data indicate that clathrin is required for the function of AP-1 (zeige FOSB ELISA Kits)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.
Sortilin (zeige SORT1 ELISA Kits) is a new alpha-Gal A receptor expressed in renal endothelial cells and that this receptor together with the M6PR (zeige IGF2R ELISA Kits) is able to internalize circulating alpha-Gal A.
Mannose receptor (MR) engagement by mesothelin (zeige MSLN ELISA Kits) GPI (zeige GNPDA1 ELISA Kits) anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody
sorting of the CD-MPR in late endosomes requires a distinct di-aromatic motif with only limited possibilities for variations
We conclude that the CI-MPR (zeige IGF2R ELISA Kits) participates in lysosomal and granular targeting of serglycin (zeige SRGN ELISA Kits) and basic proteins such as lysozyme (zeige LYZ ELISA Kits) associated with the proteoglycan (zeige Vcan ELISA Kits) in hematopoietic cells.
sortilin (zeige SORT1 ELISA Kits) and mannose-6-phosphate receptors recycle to the TGN (zeige TG ELISA Kits) in SNX1 (zeige SNX1 ELISA Kits)-dependent carriers, which we named endosome-to-TGN (zeige TG ELISA Kits) transport carriers
Missorting of cathepsin D (zeige CTSD ELISA Kits) in GARP-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.
Data demonstrate that Rab31 is required for transport of mannose 6-phosphate receptors from the trans-Golgi network to endosomes and for the Golgi/TGN (zeige TG ELISA Kits) organization.
Expression and binding properties of mannose-6-phosphate receptors CD-MPR and CI-MPR (zeige IGF2R ELISA Kits) differ during perinatal development in rat liver.
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
46-kDa mannose 6-phosphate receptor
, CD Man-6-P receptor
, Mr 46,000 Man6PR
, cation-dependent mannose-6-phosphate receptor
, small mannose 6-phosphate receptor
, 46 kDa mannose 6-phosphate receptor
, MPR 46
, mannose-6-phosphate receptor (cation dependent)
, Mannose 6-Phosphate Receptor
, Cation-dependent mannose-6-phosphate receptor
, insulin-like growth factor 2 receptor