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MVP encodes the major component of the vault complex. Zusätzlich bieten wir Ihnen Major Vault Protein Antikörper (196) und Major Vault Protein Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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Major vault protein is important in the drug resistance of cancer cells, but it requires the presence of vPARP (zeige PARP4 ELISA Kits) for full activity
Study found significant upregulation of MVP and BCRP whereas MRP1 (zeige MDM4 ELISA Kits) and UGT1A4 were unaltered in drug resistant epilepsy brains. While upregulation of BCRP was significantly higher in mesial temporal lobe epilepsy (9.34+/-0.45; p<0.05), upregulation of MVP was significantly higher in focal cortical dysplasia (2.94+/-0.65; p<0.01).
Taxus chinensis var.-mediated downregulation of MRP1 (zeige MDM4 ELISA Kits), MDR1, and LRP (zeige RPSA ELISA Kits) might contribute to the reversal of drug resistance in non-small cell lung cancer stem cells.
We believe that for the first time, genetic variants at XRCC6 (zeige XRCC6 ELISA Kits) and MVP genes are associated with risk of more aggressive disease, and would be taken into account when assessing the malignancy of prostate cancer
MVP genetic polymorphisms and haplotypes may not be associated with drug resistance of partial epilepsy in the Chinese Han population.
NSCLCs [ non-small cell lung cancer ] expressing P-gp (zeige ABCB4 ELISA Kits) [P-glycoprotein ]/LRP (zeige RPSA ELISA Kits) [ lung resistance-related protein] bear the EGFR (zeige EGFR ELISA Kits) [epidermal growth factor receptor (zeige EGFR ELISA Kits)] mutation in exon 19 or 21 easily.
The association of MVP amplification and PTEN deletion could be a potential biomarker in glioblastoma.
Bag3 (zeige BAG3 ELISA Kits)-MVP is an important complex that regulates a potent prosurvival signaling pathway and contributes to chemotherapy resistance in breast cancer
LDL increases ABCB1 (zeige ABCB1 ELISA Kits), ABCC1 (zeige ABCC1 ELISA Kits), and LRP (zeige RPSA ELISA Kits) expression in a human doxorubicin-resistant uterine sarcoma cell line.
Study demonstrates that vaults have a tumour-promoting potential by stabilizing EGFR/PI3K-mediated migration and survival pathways in human glioblastoma.
MVP may fine-tune SR-A (zeige MSR1 ELISA Kits) activity in macrophages which contributes to the development of atherosclerosis
MVP is hijacked by L. monocytogenes in order to counteract the autophagy process, a finding that could have major implications in deciphering the cellular role of vault particles.
These results suggest that up-regulation of MVP in multi-drug resistance (MDR) may involve chromatin remodeling.
Results suggest that major vault protein functions as a novel scaffold protein (zeige HOMER1 ELISA Kits) for both SHP-2 (zeige PTPN11 ELISA Kits) and Erk (zeige EPHB2 ELISA Kits).
results suggest that MVP makes a substantial contribution to epithelial cell-mediated resistance to infection
The crystal structure of the vault particle solved at 8 A resolution, together with the 2.1-A structure of the seven N-terminal domains (R1-R7) of MVP, provide an explanation for a reversible dissociation induced by low pH.
MVP is beneficial for functional recovery and axonal regrowth after spinal cord injury in adult zebrafish.
structure and cellular localization during embryonic development; findings indicate a dramatic relocalization of MVP from the cytoplasm to the nucleus during sea urchin embryogenesis
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
lung resistance-related protein
, major vault protein
, lung resistance-associated protein