anti-Lysosomal Trafficking Regulator (LYST) Antikörper

LYST encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Zusätzlich bieten wir Ihnen LYST Kits (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LYST 1130 Q99698
Anti-Maus LYST LYST 17101 P97412
Anti-Ratte LYST LYST 85419  
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Top anti-LYST Antikörper auf

Showing 4 out of 6 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged LYST is 0.03 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: LYST Antibody  - Staining of human cell line A-431 shows localization to nucleoplasm. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
Human Maus Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Maus Unkonjugiert ELISA (Capture), ELISA   100 μg Anmelden zum Anzeigen 6 bis 8 Tage

LYST Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,

Am meisten referenzierte anti-LYST Antikörper

  1. Human Monoclonal LYST Primary Antibody für ELISA - ABIN514402 : Sánchez-Guiu, Antón, García-Barberá, Navarro-Fernández, Martínez, Fuster, Couselo, Ortuño, Vicente, Rivera, Lozano: Chediak-Higashi syndrome: description of two novel homozygous missense mutations causing divergent clinical phenotype. in European journal of haematology 2013 (PubMed)

Weitere Antikörper gegen LYST Interaktionspartner

Human Lysosomal Trafficking Regulator (LYST) Interaktionspartner

  1. Pathway analysis of the genes associated with the 46 CpG sites revealed an enrichment of immune system process genes, including LYST (cg16962115, FDR = 1.24E-04), CADM1 (zeige CADM1 Antikörper) (cg21933078, FDR = 1.22E-02) and NFATC1 (zeige NFATC1 Antikörper) (cg06784563, FDR = 1.46E-02)

  2. Mutation in LYST gene is associated with hemophagocytic lymphohistiocytosis.

  3. Effects of LYST mutations in Chediak-Higashi syndrome show that LYST is involved in regulation of natural killer cell lytic activity, from lytic granule size to polarization and exocytosis, as well as endolysosomal compartment identity.

  4. Lack of LYST during endolysosomal biogenesis leads to the formation of enlarged hybrid organelles and blocks the terminal maturation of lytic granules into secretory granules.

  5. Lysosome degradation and traffcking of cargo via autophagy, endocytosis or retrograde transport are not affected by LYST depletion.

  6. involved in the regulation of phospholipase D (zeige PLD Antikörper) activity

  7. present an AR-HSP family with cerebellar ataxia and neuropathy with a novel homozygous missense mutation in the lysosomal trafficking regulator (LYST) gene. LYST is known as the causative gene for Chediak-Higashi syndrome.

  8. this is the first report of a severe early-onset Chediak-Higashi syndrome (CHS0 with a homozygous LYST/CHS1 missense mutation.

  9. gene sequencing of all exons of the lysosome trafficking regulator (CHS1/LYST) gene and revealed a nonsense mutation in exon 5 (c.925C>T, p.R309X).

  10. R1836X mutation in the LYST gene is associated with Chediak Higashi syndrome.

Mouse (Murine) Lysosomal Trafficking Regulator (LYST) Interaktionspartner

  1. Lyst as a specific regulator of TLR3 (zeige TLR3 Antikörper)- and TLR4 (zeige TLR4 Antikörper)-mediated TRIF (zeige RNF138 Antikörper) signaling pathways reveals how the regulation of the intracellular membrane trafficking network is functionally linked to specific TLR signaling pathways.

  2. results identify an association between oxidative damage to lipid membranes and the severity of Lyst-mutant phenotypes, revealing a new mechanism that contributes to pathophysiology involving LYST

  3. the Lyst(Ing3618 )allele could represent a new model for adult Chediak-Higashi syndrome with neurological impairment

  4. Apolipoprotein E (ApoE (zeige APOE Antikörper))-deficient beige mice have markedly reduced development of atherosclerotic lesions when fed a chow diet; expression of the beige mutation in all cell types involved in lesion development contributes to atheroprotection.

  5. The upregulation of LYST/Beige in infected cells functions as a host innate response to limit parasite growth.

  6. These results demonstrated that mutation of the Lyst gene can produce ocular features of human XFS (zeige FST Antikörper) (exfoliation syndrome) and suggested that LYST or LYST-interacting genes may contribute to XFS (zeige FST Antikörper).

LYST Antigen-Profil

Protein Überblick

This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined.

Genbezeichner und Symbole assoziert mit LYST

  • lysosomal trafficking regulator (LYST) Antikörper
  • lysosomal trafficking regulator (lyst) Antikörper
  • lysosomal trafficking regulator (AaeL_AAEL005066) Antikörper
  • lysosomal trafficking regulator (CpipJ_CPIJ005368) Antikörper
  • lysosomal trafficking regulator (Lyst) Antikörper
  • Beige Antikörper
  • bg Antikörper
  • CHS Antikörper
  • CHS1 Antikörper
  • D13Sfk13 Antikörper

Bezeichner auf Proteinebene für LYST

lysosomal trafficking regulator , lysosomal-trafficking regulator-like , Chediak-Higashi syndrome 1 , beige homolog , lysosomal-trafficking regulator , CHS1 homolog

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457838 Pan troglodytes
479195 Canis lupus familiaris
779601 Xenopus (Silurana) tropicalis
5565965 Aedes aegypti
6037398 Culex quinquefasciatus
100049676 Sus scrofa
100050724 Equus caballus
100150726 Danio rerio
100167205 Acyrthosiphon pisum
100339012 Oryctolagus cuniculus
100410662 Callithrix jacchus
100468700 Ailuropoda melanoleuca
100597105 Nomascus leucogenys
1130 Homo sapiens
17101 Mus musculus
85419 Rattus norvegicus
281072 Bos taurus
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