Loricrin Proteine (LOR)

LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Zusätzlich bieten wir Ihnen Loricrin Antikörper (19) und Loricrin Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
LOR 4014 P23490
Maus LOR LOR 16939 P18165
Ratte LOR LOR 502541  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Chemical His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Wheat germ Chemical GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage

LOR Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat

Weitere Proteine zu Loricrin (LOR) Interaktionspartnern

Human Loricrin (LOR) Interaktionspartner

  1. Authors report a multi-generation family with prominent ichthyosis (zeige LBR Proteine) and palmoplantar involvement due to a novel mutation in loricrin.

  2. Letter: Knockdown of either filaggrin (zeige FLG Proteine) or loricrin increases the productions of interleukin (IL)-1alpha, IL-8 (zeige IL8 Proteine), IL-18 (zeige IL18 Proteine) and granulocyte macrophage colony-stimulating factor (zeige CSF2 Proteine) in stratified human keratinocytes.

  3. Studies on human keratinocytes recognized that loricrin expression was inversely related to the expression of the cyclin-dependent kinase (zeige CDK1 Proteine) inhibitor p21 (zeige CDKN1A Proteine)

  4. two novel heterozygous frameshift mutations in exon 2 - c.646_647insGCAGCAGGTC, p.Gln216Argfs*123 and c.798_799dupT, p.Gly267Trpfs*69 in loricrin keratoderma patients

  5. Results describe a novel frameshift mutation leading to loricrin keratoderma presenting with colloidion membrane

  6. We found no mutations of Loricrin in two Progressive symmetrical erythrokeratoderma families.

  7. We describe a young man who was a collodion baby and had the typical presentation of Loricrin keratoderma. Direct DNA sequencing identified a heterozygous mutation in the loricrin gene with a single G insertion, 730insG, present in (a) the patient

  8. There were no mutations found in the LOR gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown.

  9. identified mRNA transcripts from three genes CDSN (zeige CDSN Proteine), LOR and KRT9 (zeige KRT9 Proteine), showing strong over-expression in skin samples relative to samples from forensic body fluids, making them suitable markers for skin identification

  10. VEGF (zeige VEGFA Proteine) release and the subsequent activation of VEGF receptor 2 link loricrin gene mutations to rapid cell proliferation in a cellular model of loricrin keratoderma.

Mouse (Murine) Loricrin (LOR) Interaktionspartner

  1. the late cornified envelope 1 proteins are regulated by NRF2 (zeige NFE2L2 Proteine) and are compensatory components for loricrin as determined by their localization within the loricrin knockout cell envelope via immunoelectron microscopy

  2. Oct-6 and Oct-11 contribute to the regulation of loricrin gene transcription via interaction with AP-1 factors and Sp1/Sp3.

  3. In the absence of loricrin, S. aureus nasal colonisation was significantly impaired.

  4. The decreased expression of epidermal growth factor receptor (EGFR (zeige EGFR Proteine)), E-cadherin (zeige CDH1 Proteine), occludin (zeige OCLN Proteine), and SIRT1 (zeige SIRT1 Proteine) in the skin of Flg(ft (zeige FLG Proteine)) mice, compared with those in C57BL/6J mice, is reported.

  5. These results indicate AASS (zeige AASS Proteine) knockdown decreases the lysine requirement of the cell via a reduction of lysine catabolism through the saccharopine pathway.

  6. Mice receiving the high-protein diet had greater AASS (zeige AASS Proteine) mRNA compared to mice fed the adequate protein diet.

  7. YY1 (zeige YY1 Proteine) contributes to specific loricrin gene expression in differentiated keratinocytes by suppression of its transcription in undifferentiated keratinocytes.

  8. nectin-1 (zeige PVRL1 Proteine) plays a key role in the expression of loricrin in the epidermis

  9. Skin biopsies from STAT6 (zeige STAT6 Proteine) transgenic mice were deficient in the expression and production of loricrin and involucrin (zeige IVL Proteine).

Loricrin (LOR) Protein Überblick

Protein Überblick

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

Genbezeichner und Symbole assoziert mit Loricrin Proteine (LOR)

  • loricrin (LOR)
  • loricrin (Lor)
  • loricrin (TVAG_146950)
  • loricrin (TVAG_228830)
  • loricrin (TVAG_228920)
  • loricrin (TVAG_238290)
  • loricrin (TVAG_035050)
  • loricrin (TVAG_070680)
  • Loricrin (Bm1_52290)
  • loricrin (LOC100281109)
  • loricrin (LOC100281170)
  • aminoadipate-semialdehyde synthase (Aass)
  • AI036317 Protein
  • LKR Protein
  • LKR/SDH Protein
  • LOR Protein
  • LOR/SDH Protein
  • Lorsdh Protein
  • RGD1559993 Protein
  • S77319 Protein
  • SDH Protein

Bezeichner auf Proteinebene für Loricrin Proteine (LOR)

RGD1559993 , loricrin , Loricrin , alpha-aminoadipic semialdehyde synthase, mitochondrial , lysine oxoglutarate reductase , saccharopine dehydrogenase

4014 Homo sapiens
16939 Mus musculus
502541 Rattus norvegicus
505154 Bos taurus
609440 Canis lupus familiaris
714526 Macaca mulatta
5464469 Trichomonas vaginalis G3
5465148 Trichomonas vaginalis G3
5465157 Trichomonas vaginalis G3
5467355 Trichomonas vaginalis G3
5468010 Trichomonas vaginalis G3
5468969 Trichomonas vaginalis G3
6105342 Brugia malayi
100281109 Zea mays
100281170 Zea mays
30956 Mus musculus
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