anti-Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) Antikörper

LIPA encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). Zusätzlich bieten wir Ihnen Lipase A Kits (10) und Lipase A Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LIPA 3988 P38571
LIPA 25055  
LIPA 16889 Q9Z0M5
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Top anti-Lipase A Antikörper auf antikoerper-online.de

Showing 10 out of 91 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB 0.025 mL Anmelden zum Anzeigen 7 bis 9 Tage
$161.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-LIPA AntibodyTitration: 1.0 µg/mL <br /> Positive Control: HepG2 Whole Cell <br /> LIPA is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (50 ug of whole cell lysate) A: mouse Liver 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: A549 B: H1299 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 10 bis 11 Tage
$428.57
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Liver tissue 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$360.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Liver tissue 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$380.00
Details
Human Maus Unkonjugiert IP, ELISA, WB Western Blot analysis of LIPA expression in transfected 293T cell line by LIPA monoclonal antibody (M01), clone 1F9.<br><br>Lane 1: LIPA transfected lysate(45 KDa).<br>Lane 2: Non-transfected lysate.<br> Detection limit for recombinant GST tagged LIPA is approximately 10ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert WB Western Blot analysis of LIPA expression in transfected 293T cell line by LIPA monoclonal antibody (M01), clone 1F9. Lane 1: LIPA transfected lysate(45 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged LIPA is approximately 10 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

LIPA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Rat (Rattus)


Mouse (Murine)


Am meisten referenzierte anti-Lipase A Antikörper

  1. Human Monoclonal Lipase A Primary Antibody für ELISA, WB - ABIN969484 : Drebber, Andersen, Kasper, Lohse, Stolte, Dienes: Severe chronic diarrhea and weight loss in cholesteryl ester storage disease: a case report. in World journal of gastroenterology : WJG 2005 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Lipase A Primary Antibody für ELISA, WB - ABIN966473 : Boldrini, Devito, Biselli, Filocamo, Bosman: Wolman disease and cholesteryl ester storage disease diagnosed by histological and ultrastructural examination of intestinal and liver biopsy. in Pathology, research and practice 2004 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal Lipase A Primary Antibody für WB - ABIN517528 : Roszell, Tao, Yu, Huang, Bates: Characterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lung. in American journal of physiology. Lung cellular and molecular physiology 2012 (PubMed)

  4. Horse (Equine) Polyclonal Lipase A Primary Antibody für WB - ABIN611571 : Matsuoka, Huang, Elledge: Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal Lipase A Primary Antibody für ICC, IF - ABIN4331092 : Lettieri Barbato, Tatulli, Aquilano, Ciriolo: FoxO1 controls lysosomal acid lipase in adipocytes: implication of lipophagy during nutrient restriction and metformin treatment. in Cell death & disease 2013 (PubMed)

Weitere Antikörper gegen Lipase A Interaktionspartner

Pig (Porcine) Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) Interaktionspartner

  1. Cholesterol esterase shows enantioselective inhibition for enantiomers of exo (zeige PHM Antikörper)- and endo-2-norbornyl-N-n-butylcarbamates.

Human Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) Interaktionspartner

  1. LAL activity is significantly reduced in NAFLD (zeige TSC2 Antikörper), compared to that in HCV patients. This finding is particularly evident in the pre-cirrhotic stage of disease. LAL activity is also correlated with platelet and white blood cell count, suggesting an analytic interference of portal-hypertension-induced pancytopenia on DBS (zeige MCF2L Antikörper)-determined LAL activity.

  2. LAL plays a critical role in regulating mesenchymal stem cells' ability to stimulate tumor growth and metastasis, which provides a mechanistic basis for targeting LAL in MSCs to reduce the risk of cancer metastasis

  3. Report a marked reduction of LAL activity in patients with cryptogenic cirrhosis.

  4. LIPA mutations may have a role in with a clinical diagnosis of familial hypercholesterolemia

  5. Use CRISPR/Cas9 techniques to knockout LIPA in human induced pluripotent stem cells and differentiate them to macrophages.

  6. LIPA associated with Familial Hypercholesterolemia and Polygenic Hypercholesterolemia in patients with Acute Coronary Syndrome , age /=160 mg/dl.

  7. Study demonstrates that liver cirrhosis from any etiology is characterized by a significant reduction of LAL activity but no known c.894G>A SNP, which is likely on an acquired base and independent from the etiology of hepatic disease.

  8. Coronary artery disease-associated coding variant rs1051338 causes reduced lysosomal LAL protein and activity because of increased LAL degradation.

  9. results indicate that LAL is the major acid RE hydrolase and required for functional retinoid homeostasis.

  10. These findings suggest a strong association between impaired LAL activity and Non-alcoholic fatty liver disease.

Mouse (Murine) Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) Interaktionspartner

  1. Low LAL expression is associated with tumor growth and metastasis.

  2. The activity of lysosomal acid lipase was also decreased on treatment of macrophages with each modified LDL.

  3. results indicate that LAL is the major acid RE hydrolase and required for functional retinoid homeostasis.

  4. hLAL (zeige LIPF Antikörper) expression reduced tumor-promoting myeloid-derived suppressive cells in the liver of lal(-/-) mice

  5. Results indicate that LAL has a critical role in regulating MDSCs' ability to directly stimulate cancer cell proliferation and overcome immune rejection of cancer metastasis in allogeneic mice through modulation of the mTOR (zeige FRAP1 Antikörper) pathway.

  6. effect the loss of SOAT2 (zeige SOAT2 Antikörper) function has on tissue esterified cholesterol sequestration in lysosomal acid lipase-deficient mice in a model of cholesteryl ester storage disease

  7. Lipolysis of triacylglycerol substrates by LAL is important for M2 macrophage activation, and its inhibition suppresses M2 activation.

  8. LAL regulates endothelial cell function through interaction with myeloid-derived suppressor cells and modulation of the mTOR (zeige FRAP1 Antikörper) pathway, which provide mechanistic basis for targeting MDSCs or mTOR (zeige FRAP1 Antikörper) to rejuvenate EC functions in LAL deficiency-related diseases

  9. These results indicate a crucial role of LAL-regulated mTOR signaling in the production and function of CD11b(+)Ly6G(+) cells.

  10. SR-BI (zeige SCARB1 Antikörper)-delivered HDL (zeige HSD11B1 Antikörper)-CEs are hydrolyzed by hepatic CEH (zeige EPHX2 Antikörper) and utilized for bile acid synthesi

Lipase A (LIPA) Antigen-Profil

Protein Überblick

This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit LIPA

  • lipase A, lysosomal acid type (LIPA) Antikörper
  • lipase A, lysosomal acid, cholesterol esterase (lipa) Antikörper
  • lipase A, lysosomal acid, cholesterol esterase (LIPA) Antikörper
  • lipase A, lysosomal acid, cholesterol esterase L homeolog (lipa.L) Antikörper
  • lipase A, lysosomal acid type (Lipa) Antikörper
  • lysosomal acid lipase A (Lipa) Antikörper
  • AA960673 Antikörper
  • CESD Antikörper
  • Chole Antikörper
  • Chole2 Antikörper
  • Lal Antikörper
  • Lip-1 Antikörper
  • Lip1 Antikörper
  • LIPA Antikörper

Bezeichner auf Proteinebene für LIPA

lipase A, lysosomal acid, cholesterol esterase (Wolman disease) , lysosomal acid lipase/cholesteryl ester hydrolase , lipase A, lysosomal acid, cholesterol esterase , lysosomal acid lipase/cholesteryl ester hydrolase-like , acid cholesteryl ester hydrolase , cholesterol ester hydrolase , cholesteryl esterase , lysosomal acid lipase , sterol esterase , Cholesterol esterase (pancreatic) see D3Wox12 D3Wox13 D3Wox26 and D3Mgh25 , lysosomal acid lipase 1 , lysosomal acid lipase A , pancreatic cholesterol esterase , lipase A

GENE ID SPEZIES
466150 Pan troglodytes
548564 Xenopus (Silurana) tropicalis
610650 Canis lupus familiaris
734759 Xenopus laevis
100071626 Equus caballus
100125267 Bos taurus
100142668 Sus scrofa
100145859 Ovis aries
100453604 Pongo abelii
100583764 Nomascus leucogenys
3988 Homo sapiens
25055 Rattus norvegicus
16889 Mus musculus
Ausgewählte Anbieter für anti-Lipase A (LIPA) Antikörper
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