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LILRB5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4.
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Human Polyclonal LILRB5 Primary Antibody für CyTOF, FACS - ABIN4899352
Zhang, Hatano, Shaw, Olde Nordkamp, Jiang, Li, Kollnberger: The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains. in PLoS ONE 2015
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The transcriptional profile of the orphan receptor (zeige NR1D2 Antikörper) LILRB5 is significantly up-regulated following exposure to mycobacteria.
LILRB5 binding to intracellular HLA-class I (zeige MICA Antikörper) heavy chains suggests a chaperone function
The rs12975366 in the LILRB5 gene was significantly associated with CK levels of statin users.
Mature cord-blood-derived mast cells expressed LILRB5 in cytoplasmic granules and upon cross-linking of the high-affinity IgE receptor, released LILRB5 into the culture medium.
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
, leukocyte immunoglobulin-like receptor subfamily B member 5
, leukocyte immunoglobulin-like receptor, subfamily B, member 5, isoform 1
, CD85 antigen-like family member C
, leukocyte immunoglobulin-like receptor 8
, leukocyte immunoglobulin-like receptor, subfamily B, member 5