Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Proteine (LILRA3)

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. Zusätzlich bieten wir Ihnen Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Antikörper (33) und Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
LILRA3 11026 Q8N6C8
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Top Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 Proteine auf antikoerper-online.de

Showing 9 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,570.39
Details
HEK-293 Cells Human Fc Tag Human LILRA3, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg 2 bis 3 Tage
$346.50
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg 15 bis 18 Tage
$732.00
Details
Human Cells Human His tag   50 μg 4 Days
$257.95
Details
Human Cells Human Fc Tag 100 μg 14 bis 16 Tage
$570.06
Details
Wheat germ Human GST tag 10 μg 11 bis 12 Tage
$414.29
Details
Human Cells Human His tag   10 μg 15 bis 16 Tage
$212.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$504.90
Details
HEK-293 Cells Human Fc Tag   0.1 mg 2 bis 3 Tage
$618.75
Details

LILRA3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , , ,

Weitere Proteine zu Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) Interaktionspartnern

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) Interaktionspartner

  1. Study found possible protective effect of the T allele of LILRB1 rs1061680:T>C and no association with insertion/deletion polymorphisms of LILRA3 with ankylosing spondylitis (AS)

  2. LILRA3 polymorphism is associated with Takayasu arteritis.

  3. Mutations in the genes glucokinase regulatory protein (GCKR), RNase L (RNASEL), leukocyte immunoglobulin-like receptor 3 (LILRA3), and dynein axonemal heavy chain 10 (DNAH10) segregated with elevated HDLc levels in families, while no mutations associated with low HDLc.

  4. The homozygous LILRA3 deletion is associated with a higher susceptibility for HIV disease and with a faster disease progression.

  5. Letter: LILRA3 gene deletion is not involved in the giant cell arteritis and systemic sclerosis predisposition in Spanish patients.

  6. LILRA3 significantly reversed Nogo-66-mediated inhibition of neurite outgrowth and promoted synapse formation in primary cortical neurons through regulation of the ERK/MEK pathway.

  7. Experiments point towards a beneficial role for LILRA3 in virus infections, especially in ssRNA viruses, like HIV, that engage TLR8; however, the potentially beneficial role of LILRA3 is abrogated during a HIV infection.

  8. LILRA3 gene deletion was not associated with Multiple Sclerosis susceptibility and did not affect the age of disease onset, clinical subtype or disease severity.

  9. Evidence showed lack of significant association between LILRA3 deletion and multiple sclerosis pathogenesis. [meta-analysis]

  10. LILRA3 is a new susceptibility factor for systemic lupus erythematosus (SLE) and primary Sjogren's syndrome (pSS). It predisposes to certain phenotypes such as leucopenia, thrombocytopenia, autoantibody positivity and increased disease activity.

  11. The current study was conducted to investigate the association of rs103294 of LILRA3 with benign prostatic hyperplasia risk.

  12. ILT6 deletion polymorphism does not appear to be a lupus susceptibility gene in South Indian Tamils, but may behave as a genetic modifier of autoantibody phenotype by influencing the production of anti-Ro60 and anti-Ro52 autoantibodies

  13. LILRA3 is an immunostimulatory molecule, whose deficiency is associated with higher frequency of B-non-Hodgkin's lymphoma.

  14. functional LILRA3 is a novel genetic risk factor for rheumatoid arthritis (RA), especially in males. It appears to highly predispose to ACPA-positive RA and confers an increased risk of disease severity in patients with early RA.

  15. Data did not indicate any association of LILRA3 deletion with multiple sclerosis (MS) susceptibility, however, patients negative for the deletion may begin to suffer from MS significantly earlier than patients who are positive.

  16. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2

  17. LILRA1 and LILRA3 generally display a greater binding preference for binding to HLA-C free heavy chain, particularly following removal of beta2-microglobulin by acid treatment.

  18. These results suggest that LILRA3 may play a role in chronic inflammatory conditions such as rheumatoid arthritis.

  19. A deletion of LILRA3 gene was found in a minority of British population

  20. Six alleles characterised, of which four will encode unique peptides, one of which is likely to directly influence ligand binding.

Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) Protein Überblick

Protein Überblick

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997

Genbezeichner und Symbole assoziert mit LILRA3

  • leukocyte immunoglobulin like receptor A3 (LILRA3)
  • CD85E Protein
  • e3 Protein
  • HM31 Protein
  • HM43 Protein
  • ILT-6 Protein
  • ILT6 Protein
  • LIR-4 Protein
  • LIR4 Protein

Bezeichner auf Proteinebene für LILRA3

CD85 antigen-like family member E , immunoglobulin-like transcript 6 , leucocyte immunoglobulin-like receptor , leukocyte immunoglobulin-like receptor 4 , leukocyte immunoglobulin-like receptor A3 , leukocyte immunoglobulin-like receptor subfamily A member 3 , monocyte inhibitory receptor HM43/HM31

GENE ID SPEZIES
11026 Homo sapiens
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