Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 Proteine (LGR6)

LGR6 encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. Zusätzlich bieten wir Ihnen LGR6 Antikörper (91) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
LGR6 59352 Q9HBX8
LGR6 329252 Q3UVD5
LGR6 498233  
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Showing 5 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Wheat germ Human Unkonjugiert   10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$654.29
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Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$318.85
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LGR6 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Weitere Proteine zu Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6) Interaktionspartnern

Human Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6) Interaktionspartner

  1. Inhibition of LGR6 promoted the osteogenic differentiation of bone marrow stromal cells in vitro.

  2. Lgr6 has a tumorpromoting role in the development of colorectal cancer.

  3. Lgr6 marks mammary gland progenitor cells that can initiate tumours, and cells of luminal breast tumours required for efficient tumour maintenance.

  4. Two of the three monoclonal antibodies recognized the large N-terminal extracellular domain of leucine rich repeat containing G protein-coupled receptor 6 (LGR6), and competitively blocked the binding of R-spondin 1 (zeige RSPO1 Proteine), which is known to be the ligand for LGR6.

  5. LGR6 expression is significantly downregulated in human masticatory mucosa during wound healing

  6. Overexpression of wild-type LGR6 in HeLa cells leads to increased cell migration.

Mouse (Murine) Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6) Interaktionspartner

  1. Leucine rich repeat containing G protein coupled receptor 6 (Lgr6) mRNA was found to be diminished in skin tumors.

  2. Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma whose expression is proportional with the disease progression.

  3. Lgr6 marks mammary gland progenitor cells that can initiate tumours, and cells of luminal breast tumours required for efficient tumour maintenance.

  4. Lgr6 marks nail (zeige CD244 Proteine) stem cells and is required for digit tip regeneration.

  5. Lgr6 and Bmi1 (zeige BMI1 Proteine) have roles in stem cells in the acral epithelium that participate in the long-term maintenance of sweat glands, ducts, and interadnexal epidermis, while Lgr5 (zeige LGR5 Proteine) has a role in rapid cycling and maintance of sweat glands only

  6. Lgr6 is expressed in cells at the basal area of taste buds in fungiform and circumvallate papillae. Lgr6+ cells give rise to taste bud cells in taste papillae in both anterior and posterior tongue.

  7. The members of the R-spondin family are known as activators of Wnt (zeige WNT2 Proteine) signaling, and Lgr4 (zeige LGR4 Proteine), Lgr5 (zeige LGR5 Proteine), and Lgr6 have been identified as receptors for R-spondins.

  8. Lgr5 (zeige LGR5 Proteine) has been identified as a marker of Wnt (zeige WNT2 Proteine)-regulated adult stem cell populations in the hair-follicle, intestine and stomach. A closely-related protein, Lgr6 marks adult stem cells responsible for fueling the renewal of the sebaceous gland and skin.[Review]

  9. study concludes that Lgr6 marks the most primitive epidermal stem cell

LGR6 Protein Überblick

Protein Überblick

This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit LGR6

  • leucine rich repeat containing G protein-coupled receptor 6 (LGR6)
  • leucine-rich repeat-containing G protein-coupled receptor 6 (Lgr6)
  • A530037C04Rik Protein
  • D830026M09 Protein
  • GPCR Protein
  • LGR6 Protein
  • RGD1560339 Protein
  • VTS20631 Protein

Bezeichner auf Proteinebene für LGR6

leucine-rich repeat-containing G protein-coupled receptor 6 , leucine-rich repeat-containing G-protein coupled receptor 6-like , gonadotropin receptor , leucine-rich repeat-containing G-protein coupled receptor 6

GENE ID SPEZIES
490231 Canis lupus familiaris
100052322 Equus caballus
100453009 Pongo abelii
100470324 Ailuropoda melanoleuca
100511400 Sus scrofa
59352 Homo sapiens
329252 Mus musculus
498233 Rattus norvegicus
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