anti-Leprecan Like Protein 1 (LEPREL1) Antikörper

LEPREL1 encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. Zusätzlich bieten wir Ihnen LEPREL1 Kits (6) und LEPREL1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LEPREL1 210530 Q8CG71
LEPREL1 288016 Q4KLM6
LEPREL1 55214 Q8IVL5
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Top anti-LEPREL1 Antikörper auf antikoerper-online.de

Showing 10 out of 18 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: LEPREL1 Antibody [NBP1-94041] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Immunohistochemistry-Paraffin: LEPREL1 Antibody [NBP1-94041] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using LEPREL1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
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Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: LEPREL1 Antibody [NBP1-94042] - Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells and decidual cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$390.50
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   50 μL Anmelden zum Anzeigen 13 bis 16 Tage
$313.50
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Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$420.00
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Human Kaninchen Unkonjugiert IHC (p)   100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$420.00
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Human Kaninchen Unkonjugiert IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$563.75
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$157.06
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LEPREL1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine)


Rat (Rattus)


Human ,


Am meisten referenzierte anti-LEPREL1 Antikörper

  1. Human Polyclonal LEPREL1 Primary Antibody für IHC, IHC (p) - ABIN4330688 : Fernandes, Farnand, Traeger, Weis, Eyre: A role for prolyl 3-hydroxylase 2 in post-translational modification of fibril-forming collagens. in The Journal of biological chemistry 2011 (PubMed)

Weitere Antikörper gegen LEPREL1 Interaktionspartner

Mouse (Murine) Leprecan Like Protein 1 (LEPREL1) Interaktionspartner

  1. Altered collagen prolyl 3-hydroxylation is caused by loss of P3H2.

  2. prolyl 3-hydroxylation of type IV collagen (zeige COL4 Antikörper) by P3H2 has an important function preventing maternal platelet aggregation in response to the early developing embryo

  3. P3H2 is responsible for the hydroxylation of collagen IV (zeige COL4 Antikörper), which has the highest 3-hydroxyproline content of all collagens. It is thus possible that P3H2 mutations may lead to a disease with changes in basement membranes.

  4. Study found that all 3 mouse Leprecan (zeige LEPRE1 Antikörper) genes Lepre1 (zeige LEPRE1 Antikörper), leprel1 and leprel2 (zeige LEPREL2 Antikörper) are expressed in the notochord; additionally, they are expressed in dorsal root ganglia, limb buds, branchial arches, and developing kidneys.

  5. This report characterizes expression of the P3H1 (zeige LEPRE1 Antikörper), P3H2 and P3H3 (zeige LEPREL2 Antikörper) genes in embryonic and adult mice.

Human Leprecan Like Protein 1 (LEPREL1) Interaktionspartner

  1. Recessive LEPREL1 mutations should be recognized as part of the differential diagnosis of lens subluxation.

  2. LEPREL1 plays an important role in eye development and homozygous loss-of-function mutation of this gene can cause severely high myopia and early-onset cataract.

  3. mutation in LRPAP1 is associated with high myopia. Further studies are expected to evaluate the pathogenicity of the variants in CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2.

  4. High myopia is caused by a mutation in LEPREL1, encoding prolyl 3-hydroxylase 2.

  5. P3H2 has preferred substrate sequences among the classes of 3Hyp sites in clade A collagen chains

  6. P3H2 is responsible for the hydroxylation of collagen IV (zeige COL4 Antikörper), which has the highest 3-hydroxyproline content of all collagens. It is thus possible that P3H2 mutations may lead to a disease with changes in basement membranes.

  7. The restriction of silencing in P3H2 to breast carcinomas, and its association with oestrogen-receptor-positive cases, suggests that P3H2 may be a breast-cancer-specific tumour suppressor.

LEPREL1 Antigen-Profil

Protein Überblick

This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit LEPREL1

  • prolyl 3-hydroxylase 2 (P3h2) Antikörper
  • prolyl 3-hydroxylase 2 (P3H2) Antikörper
  • 4832416N06 Antikörper
  • AW553532 Antikörper
  • MCVD Antikörper
  • MLAT4 Antikörper
  • P3H2 Antikörper

Bezeichner auf Proteinebene für LEPREL1

leprecan-like protein 1 , myxoid liposarcoma associated protein 4 , prolyl 3-hydroxylase 2 , myxoid liposarcoma-associated protein 4 , prolyl 3-hydroxylase 3

GENE ID SPEZIES
210530 Mus musculus
288016 Rattus norvegicus
55214 Homo sapiens
414143 Gallus gallus
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