Left-Right Determination Factor 2 (LEFTY2) ELISA Kits

LEFTY2 encodes a member of the TGF-beta family of proteins. Zusätzlich bieten wir Ihnen LEFTY2 Antikörper (59) und LEFTY2 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
LEFTY2 7044 O00292
LEFTY2 13590 Q64280
Anti-Ratte LEFTY2 LEFTY2 289316  
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Top LEFTY2 ELISA Kits auf antikoerper-online.de

Showing 2 out of 8 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus 5.5 pg/mL 15.62 pg/mL - 1000 pg/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Human 1.95 pg/mL 7.8-500 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für LEFTY2 Interaktionspartner

Human Left-Right Determination Factor 2 (LEFTY2) Interaktionspartner

  1. LEFTY2 down-regulates MKi67 (zeige MKI67 ELISA Kits) expression and FAK (zeige PTK2 ELISA Kits) activity, up-regulates miR (zeige MLXIP ELISA Kits)-200a and E-cadherin (zeige CDH1 ELISA Kits), and is thus a powerful negative regulator of endometrial cell proliferation and migration.

  2. LEFTY2 regulates the expression and activity of ENaC (zeige SCNN1A ELISA Kits) in endometrial epithelial cells via SGK1 (zeige SGK1 ELISA Kits).

  3. Lefty A may account for the tumor suppressive activity of human adult stem cells.

  4. Findings suggest that Lefty2 is negatively modulated by miR (zeige MLXIP ELISA Kits)-302s in hESCs, which plays an important role in maintaining the balance between pluripotency and germ layer specification.

  5. findings show that the TGFB4 (ebaf) mRNA has distinct tumor specific expression

  6. nodal and the inhibitors of Nodal signaling, lefty-A and lefty-B, are down-regulated very early upon differentiation of human embryonic stem cells

  7. Addition of recombinant LEFTY-A to explants induced MMP-9 (zeige MMP9 ELISA Kits) in most samples, a response prevented by ovarian steroids.

  8. LEFTY proteins, which are known to play a major role during mouse gastrulation, are transiently expressed during human embryonic stem cell differentiation.

Mouse (Murine) Left-Right Determination Factor 2 (LEFTY2) Interaktionspartner

  1. results show that TET-mediated oxidation of 5-methylcytosine modulates Lefty-Nodal signalling by promoting demethylation in opposition to methylation by DNMT3A and DNMT3B; findings reveal a fundamental epigenetic mechanism featuring dynamic DNA methylation and demethylation crucial to regulation of key signalling pathways in early body plan formation

  2. LEFTY2 regulates the expression and activity of ENaC (zeige SCNN1A ELISA Kits) in endometrial epithelial cells via SGK1 (zeige SGK1 ELISA Kits).

  3. Results indicate that microRNA miR (zeige MLXIP ELISA Kits)-127 accelerates mesendoderm differentiation of embryonic stem cells through nodal signaling by targeting left-right determination factor 2 (Lefty2).

  4. exogenous lefty1 (zeige LEFTY1 ELISA Kits) administered to mice restored the endogenous expression levels of lefty1 (zeige LEFTY1 ELISA Kits). The present study demonstrated that lefty1 (zeige LEFTY1 ELISA Kits) attenuated renal interstitial injury by inhibiting the Smaddependent TGFb1 (zeige TGFB1 ELISA Kits) signaling pathway

  5. Lefty-1 (zeige LEFTY1 ELISA Kits) may prevent TGFB1 (zeige TGFB1 ELISA Kits)-induced fibroblast-myofibroblast transdifferentiation in part via modulation of Smad3 (zeige SMAD3 ELISA Kits), JNK-3, and BMP-5 (zeige BMP5 ELISA Kits) signaling.

  6. The expression of lefty in RCC (zeige XRCC1 ELISA Kits) cells was lower than that in adjacent non-tumor cells, which may result in the overexpression of nodal, thereby promoting the growth of RCC (zeige XRCC1 ELISA Kits).

  7. Studies indicate that the pair of Nodal and Lefty (Lefty1 and Lefty2) has a conserved role in left-right asymmetry.

  8. Taken together, these results suggest that optimal expression of Lefty1 (zeige LEFTY1 ELISA Kits) and Lefty2 is critical for the balanced differentiation of mESCs into three germ layers.

  9. Beta-catenin (zeige CTNNB1 ELISA Kits) can recruit the H3K4me2/1 demethylase (zeige MBD2 ELISA Kits) LSD1 (zeige KDM1A ELISA Kits) to regulate the expression of the tumor suppressor Lefty1 (zeige LEFTY1 ELISA Kits) in mouse embryonic stem cells.

  10. Lefty can antagonise TGF-beta1 (zeige TGFB1 ELISA Kits) mediated epithelial-mesenchymal transition in renal tubular epithelial cells.

Zebrafish Left-Right Determination Factor 2 (LEFTY2) Interaktionspartner

  1. results indicate that differential diffusivity is the major determinant of the differences in Nodal/Lefty range and provide biophysical support for reaction-diffusion models of activator/inhibitor-mediated patterning

  2. we find that Cyclops is specifically required for the maintenance of lefty1 (zeige LEFTY1 ELISA Kits) and lefty2 transcription

  3. study reports that microRNA-430 (miR (zeige MYLIP ELISA Kits)-430) dampens and balances the expression of the transforming growth factor-beta (TGF-beta) Nodal agonist squint and the TGF-beta (zeige TGFB1 ELISA Kits) Nodal antagonist lefty

LEFTY2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit LEFTY2

  • left-right determination factor 2 (LEFTY2) Antikörper
  • left right determination factor 1 (Lefty1) Antikörper
  • lefty2 (lft2) Antikörper
  • left-right determination factor 2 (Lefty2) Antikörper
  • Left-right determination factor 2 (Lefty2) Antikörper
  • left-right determination factor 2 (LOC699676) Antikörper
  • left-right determination factor 2-like (LOC100232580) Antikörper
  • 6030463A22Rik Antikörper
  • AI450052 Antikörper
  • atv2 Antikörper
  • AV214969 Antikörper
  • cb720 Antikörper
  • Ebaf Antikörper
  • Ebaf2 Antikörper
  • fe38b03 Antikörper
  • Lefta Antikörper
  • Leftb Antikörper
  • lefty Antikörper
  • lefty-1 Antikörper
  • LEFTYA Antikörper
  • Stra3 Antikörper
  • Tgfb4 Antikörper
  • wu:fe38b03 Antikörper

Bezeichner auf Proteinebene für LEFTY2

TGF-beta-4 , endometrial bleeding-associated factor , left-right determination factor A , protein lefty-2 , protein lefty-A , transforming growth factor beta-4 , left-right determination factor 1 , left-right determination, factor B , protein lefty-1 , stimulated by retinoic acid gene 3 protein , endometrial bleeding associated factor , left-right determination factor B , left-right determination, factor A , protein lefty-B , left-right determination factor 2 , lefty , left-right determination factor 2-like

7044 Homo sapiens
13590 Mus musculus
30146 Danio rerio
320202 Mus musculus
534018 Bos taurus
100337677 Sus scrofa
289316 Rattus norvegicus
395529 Gallus gallus
457780 Pan troglodytes
699676 Macaca mulatta
100232580 Taeniopygia guttata
100435327 Pongo abelii
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