anti-LYR Motif Containing 4 (LYRM4) Antikörper

Required for nuclear and mitochondrial iron-sulfur protein biosynthesis (By similarity). Zusätzlich bieten wir Ihnen LYR Motif Containing 4 Kits (11) und LYR Motif Containing 4 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LYRM4 57128 Q9HD34
LYRM4 380840 Q8K215
LYRM4    
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Top anti-LYR Motif Containing 4 Antikörper auf antikoerper-online.de

Showing 10 out of 24 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow cytometric analysis of MDA-MB435 cells using LYRM4 Antibody (Center) Cat.-No AP52570PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue reacted with LYRM4 Antibody (Center) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB LYRM4 Antibody (Center) (ABIN654638) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: LYRM4 Antibody [NBP1-79672] - Human Skin Western Blot: LYRM4 Antibody [NBP1-79672] - Mouse Liver Lysate 1ug/ml Gel Concentration 10-20% 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$556.31
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis in MDA-MB435 cell line lysates (35ug/lane). LYRM4 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Immunofluorescent staining of human cell line U-251 MG with LYRM4 polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleus. Immunohistochemical staining of human hippocampus with LYRM4 polyclonal antibody  shows strong cytoplasmic positivity in neuronal cells at 1:50-1:200 dilution. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$460.00
Details
Human Kaninchen Unkonjugiert WB Western Blot showing Lyrm4 antibody used at a concentration of 1.0 ug/ml against Mouse Liver Lysate 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$473.93
Details
Human Kaninchen Unkonjugiert FACS, IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
Details
Human Kaninchen APC FACS, IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

Am meisten referenzierte anti-LYR Motif Containing 4 Antikörper

  1. Human Polyclonal LYRM4 Primary Antibody für IHC, IHC (p) - ABIN4894050 : Lim, Friemel, Marum, Tucker, Bruno, Riley, Christodoulou, Kirk, Boneh, DeGennaro, Springer, Mootha, Rouault, Leimkühler, Thorburn, Compton: Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. in Human molecular genetics 2013 (PubMed)

Weitere Antikörper gegen LYR Motif Containing 4 Interaktionspartner

Human LYR Motif Containing 4 (LYRM4) Interaktionspartner

  1. analysis of the NFS1 (zeige NFS1 Antikörper)-ISD11-ACP (zeige NDUFAB1 Antikörper) (SDA) complex forms the core of the iron-sulfur (Fe-S) assembly complex and associates with assembly proteins ISCU2 (zeige ISCU Antikörper), frataxin (FXN (zeige FXN Antikörper)), and ferredoxin to synthesize Fe-S clusters

  2. Human Isd11 (ISD11) is a helical protein which exists in solution as an equilibrium between monomer, dimeric and tetrameric species when in the absence of human Nfs1 (NFS1 (zeige NFS1 Antikörper)). Recombinant ISD11 expressed in E. coli co-purifies with the bacterial orthologue of NFS1 (zeige NFS1 Antikörper), IscS (zeige NFS1 Antikörper).

  3. The NFS1 (zeige NFS1 Antikörper)/ISD11 complex further interacts with scaffold protein (zeige HOMER1 Antikörper) ISCU (zeige ISCU Antikörper) and regulator protein frataxin (zeige FXN Antikörper), thereby forming a quaternary complex for Fe-S cluster formation.

  4. Molecular dynamics flexible fitting of protein structures docked into the EM map of the model revealed a [FXN (zeige FXN Antikörper)(42-210)]24.[NFS1 (zeige NFS1 Antikörper)]24.[ISD11]24.[ISCU (zeige ISCU Antikörper)]24 complex, consistent with the measured 1:1:1:1 stoichiometry of its four components.

  5. Our findings highlight that the ISD11 R68A/R68L mutation display reduced affinity to form a stable subcomplex with NFS1 (zeige NFS1 Antikörper), and thereby fails to prevent NFS1 (zeige NFS1 Antikörper) aggregation resulting in impairment of the Fe-S cluster biogenesis

  6. Homozygous mutation in LYRM4 was reported in two patients with combined oxidative phosphorylation deficiency.

  7. LYRM4 downregulation may be one of the mechanisms involved in inefficient oxidative phosphorylation and oxidative stress, increasingly recognised as contributors to schizophrenia pathogenesis.

  8. Frataxin (zeige FXN Antikörper) interacts with ISD11 and multiple mitochondrial chaperones.

  9. ISD11 is important in the biogenesis of Fe-S clusters in mammalian cells.

LYR Motif Containing 4 (LYRM4) Antigen-Profil

Protein Überblick

Required for nuclear and mitochondrial iron-sulfur protein biosynthesis (By similarity).

Genbezeichner und Symbole assoziert mit LYRM4

  • LYR motif containing 4 (LYRM4) Antikörper
  • LYR motif containing 4 (lyrm4) Antikörper
  • LYR motif containing 4 (Lyrm4) Antikörper
  • LYR motif containing 4 L homeolog (lyrm4.L) Antikörper
  • BC034664 Antikörper
  • C6orf149 Antikörper
  • CGI-203 Antikörper
  • Gm903 Antikörper
  • ISD11 Antikörper
  • MGC80863 Antikörper
  • si:ch73-86n6.2 Antikörper

Bezeichner auf Proteinebene für LYRM4

LYR motif-containing protein 4 , LYR motif containing 4 , homolog of yeast Isd11 , mitochondrial matrix Nfs1 interacting protein

GENE ID SPEZIES
420874 Gallus gallus
462409 Pan troglodytes
100379678 Xenopus (Silurana) tropicalis
57128 Homo sapiens
380840 Mus musculus
614011 Bos taurus
446871 Xenopus laevis
100190252 Taeniopygia guttata
100302660 Danio rerio
101788367 Cavia porcellus
101109130 Ovis aries
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