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LHX9 encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors.
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Human Polyclonal LHX9 Primary Antibody für IHC, IHC (p) - ABIN4330942
Li, Ponten, dos Remedios: The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. in Proteomics 2012
the Lhx9-integrin-paxillin (zeige PXN Antikörper) pathway has a role in proepicardial organ positioning and epicardial formation
Substantial evidence is found for the existence of a ventral pallium, based on Lhx9 expression in the forebrain during larval development and in the adult.
while FGF signalling initiates and maintains brain XLhx9 expression, in the eye primordium the requirement of FGFs for expression is rapidly lost.
Lhx9 is sufficient to specify Hcrt (zeige OX Antikörper)-expressing neurons in the developing mouse hypothalamus.
Lack of Lhx2 (zeige LHX2 Antikörper)/Lhx9 function as well as increased Wnt (zeige WNT2 Antikörper) signaling alter the expression of the thalamus specific cell adhesion factor pcdh10b and lead subsequently to a striking anterior-posterior disorganization of the caudal (zeige CAD Antikörper) forebrain.
Lhx9 and Lhx1 (zeige LHX1 Antikörper) serve as a binary switch in controlling the rostral versus caudal (zeige CAD Antikörper) longitudinal turning of the caudal (zeige CAD Antikörper) commissural axons. Lhx1 (zeige LHX1 Antikörper) determines caudal (zeige CAD Antikörper) turning and Lhx9 triggers rostral turning.
LHX9 gene is frequently silenced in pediatric malignant astrocytomas
Authors examined the expression pattern for the three alternative splice forms of Lhx9; Lhx9alpha, Lhx9beta and Lhx9c during early limb development.
Study has revealed that Lhx9 plays a role in the development of the pineal gland and in maintenance of the brain structure.
Lhx9-GCE mouse line could serve as a beneficial tool for lineage tracing and gene manipulation experiments.
Gbx2 (zeige GBX2 Antikörper) regulates thalamocortical axon guidance by modifying the LIM (zeige PDLIM5 Antikörper) and Robo codes.
a pathway in which the products of the Wt1 (zeige WT1 Antikörper) and Lhx9 genes activate expression of Sf1 (zeige SF1 Antikörper) and thus mediate early gonadogenesis
the Lhx9 gene represents the first direct target of the GATA4 (zeige GATA4 Antikörper)/FOG2 (zeige ZFPM2 Antikörper) repressor complex in cardiac development.
Lhx2 (zeige LHX2 Antikörper)/9 regulate directly the expression of Rig-1 (zeige ROBO3 Antikörper). And expressed by a set of commissural relay neurons and are required for the this neuron axon projection.
The second wave of expression at E12.5 includes Lhx3 (zeige LHX3 Antikörper), 5, 9, Isl2 (zeige ISL2 Antikörper), and Lmx1b (zeige LMX1B Antikörper) in the differentiating sensory epithelia with cellular specificities.
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.
LIM homeobox 9
, LIM homeobox protein 9
, LIM/homeobox protein Lhx9
, LIM/homeobox protein Lhx9-like
, LIM homeodomain type transcription factor Lhx9
, homeobox protein
, LIM-homeobox protein 9
, LIM homeobox 9-like
, LIM-homeodomain type transcription factor 9