anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) Antikörper

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Zusätzlich bieten wir Ihnen KLRG1 Proteine (10) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KLRG1 50928 O88713
KLRG1 10219 Q96E93
KLRG1 58975 Q64335
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Top anti-KLRG1 Antikörper auf antikoerper-online.de

Showing 10 out of 167 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$291.53
Details
Maus Kaninchen Alexa Fluor 488 FACS Detection of KLRG1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Mouse Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$189.84
Details
Maus Kaninchen PE FACS Detection of KLRG1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Mouse Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$201.14
Details
Maus Kaninchen Unkonjugiert FACS Detection of KLRG1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody. 200 μL Anmelden zum Anzeigen 8 bis 9 Tage
$246.34
Details
Maus Hamster Unkonjugiert FACS NK1.1 positive / CD3 negative C57BL/6 mouse splenocytes were stained with Hamster Anti-Mouse KLRG1-PE. 0.5 mg Anmelden zum Anzeigen 3 bis 4 Tage
$326.40
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: HeLa 12% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Maus Golden Syrian Hamster Biotin FACS   0.1 mg Anmelden zum Anzeigen 15 bis 18 Tage
$240.18
Details
Human Golden Syrian Hamster APC FACS 100 μg Anmelden zum Anzeigen 10 bis 12 Tage
$292.47
Details
Human Golden Syrian Hamster FITC FACS, IP Flow Cytometry: KLRG1 Antibody (2F1) [FITC] [NBP1-28116] - Analysis of C57BL/6 splenocytes by multiple staining. 0.25 mg Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
Details
Maus Hamster PE FACS Detection of KLRG1 in Mouse Splenocytes by Flow Cytometry. C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody  Hamster IgG Phycoerythrin Isotype Control. 100 μg Anmelden zum Anzeigen 9 bis 11 Tage
$319.79
Details

Am meisten referenzierte anti-KLRG1 Antikörper

  1. Mouse (Murine) Monoclonal KLRG1 Primary Antibody für FACS - ABIN2689801 : Beyersdorf, Ding, Karp, Hanke: Expression of inhibitory "killer cell lectin-like receptor G1" identifies unique subpopulations of effector and memory CD8 T cells. in European journal of immunology 2001 (PubMed)
    Show all 7 Pubmed References

  2. Mouse (Murine) Monoclonal KLRG1 Primary Antibody für FACS - ABIN1176845 : Corral, Hanke, Vance, Cado, Raulet: NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules. in European journal of immunology 2000 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Monoclonal KLRG1 Primary Antibody für FACS - ABIN135349 : Nakamura, Niemi, Fisher, Shultz, Seaman, Ryan: Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. in The Journal of experimental medicine 1997 (PubMed)
    Show all 5 Pubmed References

  4. Mouse (Murine) Monoclonal KLRG1 Primary Antibody für FACS - ABIN2475242 : Hanke, Corral, Vance, Raulet: 2F1 antigen, the mouse homolog of the rat "mast cell function-associated antigen", is a lectin-like type II transmembrane receptor expressed by natural killer cells. in European journal of immunology 1999 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal KLRG1 Primary Antibody für ELISA, WB - ABIN564422 : Yoon, Lim, Park, Lee: Cell-to-cell contact with hepatitis C virus-infected cells reduces functional capacity of natural killer cells. in Journal of virology 2011 (PubMed)

  6. Monoclonal KLRG1 Primary Antibody für FACS, IP - ABIN534907 : Burshtyn, Scharenberg, Wagtmann, Rajagopalan, Berrada, Yi, Kinet, Long: Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor. in Immunity 1996 (PubMed)
    Show all 3 Pubmed References

  7. Mouse (Murine) Monoclonal KLRG1 Primary Antibody für FACS - ABIN376381 : Tan, Sande, Pufnock, Blattman, Greenberg: Retinoic acid as a vaccine adjuvant enhances CD8+ T cell response and mucosal protection from viral challenge. in Journal of virology 2011 (PubMed)

  8. Human Polyclonal KLRG1 Primary Antibody für ELISA - ABIN4228594 : Marcolino, Przybylski, Koschella, Schmidt, Voehringer, Schlesier, Pircher: Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history. in European journal of immunology 2004 (PubMed)

Weitere Antikörper gegen KLRG1 Interaktionspartner

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) Interaktionspartner

  1. This paper demonstrates that developmental plasticity of KLRG1(+) effector CD8(+) T cells is important in promoting functionally versatile memory cells and long-term protective immunity.

  2. KLRG1 expression identifies short-lived Foxp3(+) Treg effector cells with functional plasticity in islets of NOD mice.

  3. Treg cell accumulation in intestinal tumours from APC(min/+) mice was exclusively due to the increase in KLRG1(+) GATA3(+) Treg cells.

  4. Although absence of KLRG1 is not enough to increase intestinal Treg cells in KLRG1 knockout mice, KLRG1 ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.

  5. Ly6C, 4-1BB, and KLRG1 have roles in the activation of lamina propria lymphocytes in the small intestine in a mouse model of Crohn's disease

  6. This finding provides a rationale for the reciprocal expression of KLRG1 and CD103 in different CD8(+) T-cell subsets.

  7. Cytotoxic KLRG1-expressed CD8 effector cells and defective T regulatory cells cause murine autoimmune cholangitis.

  8. KLRG1(+) iNKT cells coexpressing CD49d and granzyme A persisted for several months and displayed a potent secondary response to cognate antigen.

  9. high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 inhibitory function, indicating that TfRs may sequester KLRG1 from interacting with cadherins.

  10. data further demonstrate that the inhibitory activity of KLRG1 is decreased in T cells expressing high levels of TfR, indicating that association of KLRG1 with TfR hinders KLRG1-mediated silencing.

  11. Data indicate that CD103(+)CD8(+) T(RM) cells developed in the skin from epithelium-infiltrating precursor cells that lacked expression of the effector-cell marker KLRG1.

  12. Data indicate that increments of CD8 + effector memory T cells in human and mouse chronic lymphocytic leukemia (CLL)(Emu-TCL1 model) were due to an expansion of the inhibitory killer cell lectin-like receptor G1 (KLRG1) expressing cellular subset.

  13. Despite their differences, KLRG1+ and KLRG1- Treg cells proved similarly potent in suppressing experimental autoimmune encephalomyelitis.

  14. KLRG1(-/-) mice had a significant survival extension after Mycobacterium tuberculosis infection compared to wild-type controls, and maintained a significantly lower level of pulmonary bacterial load throughout chronic infection.

  15. CD8+ T cells lacking Id2 do not generate a robust terminally differentiated killer cell lectin-like receptor G1 (KLRG1hi) effector population, but display a cell-surface phenotype and cytokine profile consistent with memory precursors.

  16. The lower inhibitory capacity of mKLRG1 compared with hKLRG1 can thus be rationalized by a decreased proportion of dimeric entities, which can be pinpointed to a single amino acid.

  17. KLRG1high-expressiong CD8 T cells isolated from the lung during the peak of influenza infection could long survive in vitro and participate in a recall response to influenza virus infection upon adoptive transfer.

  18. T-cell co-inhibitory blockade combined with alphaCTLA-4 and active co-stimulation with alpha4-1BB promotes rejection of B16 melanoma in with a vaccine; KLRG1 is a useful marker for monitoring the anti-tumor immune response elicited by this therapy

  19. The KLRG1+NKG2A+ positive phenotype correlates with protective efficacy for generating effector and proliferative memory responses from a pool of CD8 T cells during persistent gamma-herpesvirus 68 infection.

  20. Interleukin-2-activated natural killer cells interact with tumor necrosis factor-alpha-stimulated endothelial cells to induce their proliferation and promote angiogenesis through a mechanism involving alpha4beta7 integrin and KLRG1.

Human Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) Interaktionspartner

  1. KLRG1 might contribute to the impaired antitumor immunity of memory T cells in tumor microenvironment

  2. Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase

  3. The results suggest that a disease-associated SNP located within the 3'UTR of KLRG1 directly interferes with miR-584-5p binding, allowing for KLRG1 mRNA differential accumulation, which in turn may contribute to pathogenesis of pemphigus.

  4. Demonstrate the presence of increased KLRG1-expressing T-cells in tuberculosis-treated individuals, and present KLRG1 as a marker of decreased human T-cell proliferation following BCG-vaccination.

  5. This finding provides a rationale for the reciprocal expression of KLRG1 and CD103 in different CD8(+) T-cell subsets.

  6. high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 inhibitory function, indicating that TfRs may sequester KLRG1 from interacting with cadherins.

  7. More T cells were KLRG1+ in the synovial fluid of patients with spondylarthritis/rheumatoid arthritis than crystal arthritis or controls. Those T cells were more functionally active, and migrated towards the synovial fluid of SpA/RA patients.

  8. KLRG1 was overexpressed on CD4(+) T cells.

  9. Data indicate that increments of CD8 + effector memory T cells in human and mouse chronic lymphocytic leukemia (CLL)(Emu-TCL1 model) were due to an expansion of the inhibitory killer cell lectin-like receptor G1 (KLRG1) expressing cellular subset.

  10. These results indicate that KLRG1 negatively regulates natural killer cell numbers and functions via the Akt pathway, thus providing a novel marker and therapeutic target for hepatitis C virus infection.

  11. The lower inhibitory capacity of mKLRG1 compared with hKLRG1 can thus be rationalized by a decreased proportion of dimeric entities, which can be pinpointed to a single amino acid.

  12. cytomegalovirus positive had lower proportions of NK-cells expressing inhibitory receptors (KLRG1 and CD158a)

  13. trastuzumab-mediated antibody-dependent cellular cytotoxicity was markedly enhanced by KLRG1-negative peripheral blood mononuclear cells

  14. Results demonstrated a substantial reduction in both CD94- and KLRG1- expressing CD3(-)CD56(+) NK cells with increased age.

  15. Expression of MafA analyzed in conditional knockout mice during embryonic development is the first specific marker of a subpopulation of "early c-ret" positive sensory neurons.

  16. human effector and memory T cells expressing KLRG1 lack proliferative capacity

  17. KLRG1 expression discriminated between cord blood T cells that differed in their post-thymic expansion rate

  18. KLRG1 is expressed in the overwhelming majority of CD8-positive T cells specific for epitopes of cytomegalovirus or Epstein- Barr virus during the latent stage; a slightly lower KLRG1 expression level is observed in HIV-specific T8 cells.

  19. virus-specific CD8+ T cells are mostly KLRG1+ in chronic viral infections (human immunodeficiency virus, cytomegalovirus, and Epstein-Barr virus) but not in resolved infection (influenza virus)

  20. peripheral HCV-specific CD8+ T cells were CD127+ and KLRG1-; Intrahepatic virus-specific CD8+ T cells displayed significantly reduced levels of CD127 expression but similar levels of KLRG1 expression compared to the peripheral blood.

KLRG1 Antigen-Profil

Protein Überblick

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined.

Genbezeichner und Symbole assoziert mit KLRG1

  • killer cell lectin like receptor G1 (KLRG1) Antikörper
  • killer cell lectin-like receptor subfamily G, member 1 (Klrg1) Antikörper
  • killer cell lectin like receptor G1 (Klrg1) Antikörper
  • 2F1 Antikörper
  • 2F1-Ag Antikörper
  • CLEC15A Antikörper
  • KLRG1 Antikörper
  • MAFA Antikörper
  • MAFA-2F1 Antikörper
  • MAFA-L Antikörper
  • MAFA-LIKE Antikörper

Bezeichner auf Proteinebene für KLRG1

killer cell lectin-like receptor subfamily G, member 1 , killer cell lectin-like receptor subfamily G member 1 , mast cell function-associated antigen 2F1 , C-type lectin domain family 15 member A , C-type lectin domain family 15, member A , ITIM-containing receptor MAFA-L , MAFA-like receptor , mast cell function-associated antigen (ITIM-containing) , mast cell function-associated antigen

GENE ID SPEZIES
611464 Canis lupus familiaris
736225 Pan troglodytes
50928 Mus musculus
10219 Homo sapiens
58975 Rattus norvegicus
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