anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4) Antikörper

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Zusätzlich bieten wir Ihnen Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 Proteine (6) und Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KIR2DS4 3809 P43632
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Top anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 Antikörper auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$537.17
Details
Human Maus Unkonjugiert ELISA, WB 100 μL 11 bis 14 Tage
$522.50
Details
Human Maus Unkonjugiert EIA, WB Western blot analysis Recombinant human KIR2DL1, KIR2DL3, KIR2DL4 and KIR2DS4 (each 100 ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DS4 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Arrow indicates recombinant human KIR2DS4 protein. 0.1 mL 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Western Blot; Sample: Rat Serum; Primary Ab: 2µg/mL Rabbit Anti-Human KIR2DS4 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 bis 16 Tage
$332.00
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extract of 293T cells, using KIR2DS4 antibody. Immunofluorescence analysis of U2OS cells using KIR2DS4 antibody (ABIN1875414) at dilution of 1:100. Blue: DAPI for nuclear staining. 100 μL 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of 293T cells, using KIR2DS4 antibody. 200 μL 12 bis 14 Tage
$438.90
Details
Human Kaninchen Unkonjugiert WB   100 μL 11 bis 14 Tage
$390.50
Details
Human Kaninchen Biotin WB   100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen FITC WB   100 μL 11 bis 14 Tage
$566.50
Details
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL 14 bis 21 Tage
$428.45
Details

Am meisten referenzierte anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 Antikörper

  1. Human Monoclonal KIR2DS4 Primary Antibody für FACS - ABIN4898690 : Béziat, Dalgard, Asselah, Halfon, Bedossa, Boudifa, Hervier, Theodorou, Martinot, Debré, Björkström, Malmberg, Marcellin, Vieillard: CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. in European journal of immunology 2012 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal KIR2DS4 Primary Antibody für IF (p), IHC (p) - ABIN748478 : Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers. in Archivum immunologiae et therapiae experimentalis 2014 (PubMed)

  3. Human Monoclonal KIR2DS4 Primary Antibody für CyTOF, FACS - ABIN4900805 : Kennedy, Chazara, Gardner, Ivarsson, Farrell, Xiong, Hiby, Colucci, Sharkey, Moffett: Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy. in Journal of immunology (Baltimore, Md. : 1950) 2017 (PubMed)

Weitere Antikörper gegen Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 Interaktionspartner

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4) Interaktionspartner

  1. Promoter methylation decreased and gene expression increased for KIR2DS4 after acute exercise. Chronic exercise resulted in a minor decrease of DNA methylation and did not alter gene expression.

  2. KIR2DS4 was associated with significant reduced incidence of relapse of hematological malignancies after hematopoietic stem cell transplantation from matched sibling

  3. KIR 2D (L1, L3, L4, S4) and KIR 3DL1 expression was correlated with poor prognosis in non-small cell lung carcinoma patients.

  4. KIR2DS4, KIR2DS1, and some alleles of KIR2DS5 contribute to successful pregnancy suggests that activation of uNK cells by KIR binding to HLA-C is a generic mechanism promoting trophoblast invasion into the decidua.

  5. Our findings suggest that KIR2DS4*00101 may offer a molecular biomarker to identify intrinsically milder forms of glioblastoma

  6. Data indicate the allelic diversity of KIR2DS4 proteni among ethnic Hans from southern China, which may provide data for transplantation as well as studies on KIR-associated disease and evolution.

  7. this study shows that the expression of full-length KIR2DS4 allele variants may contribute to a worse clinical outcome after hematopoietic stem cell transplantation

  8. Type 1 pediatric autoimmune hepatitis patients show increased frequency of KIR2DS4-Full Length, which in combination with HLA-DRB1*1301 revealed a strong synergistic effect. Adult autoimmune hepatitis cases have shown a weaker increased frequency of KIR2DS4-FL, a lack of synergistic effect with HLA class II antigens.

  9. Collectively, our data suggest that the KIR 2DS4/1D allelic variance is associated with the outcome of sibling-related HLA-matched HSCT, and that donor subclassification of KIR 2DS4/1D alleles should be considered in this setting.

  10. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2, KIR2DS4, KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  11. genetic polymorphism is associated with the course of Hepatitis C virus infection and the response to therapy

  12. KIR2DS4 can induce the uptake of CCR7 by KIR2DS4(+) NKG2A(+) natural killer cell clones after interacting with CCR7(+) target cells expressing HLA-Cw4 and HLA-Cw6 alleles.

  13. Study shows KIR3DL1 and KIR2DS4 gene variants are linked and that the gene KIR2DS5 is only present in the telomeric half of the KIR locus. Study revealed novel insights in the highly organized distribution of KIR genes.

  14. These results highlight the impact of population allele frequency on viral control and identify a novel association between HLA-C04 : 01 in combination with KIR2DS4f and uncontrolled HIV infection.

  15. KIR2DS4del presence in patients was associated with severity of endometriosis, which, due to strong negative linkage disequilibrium, may suggest an indirect effect of KIR2DS5 absence

  16. Response of rheumatoid arthritis patients with medium ESR values to methotrexate treatment may be dependent on the full-length KIR2DS4 gene.

  17. lower genotype frequency in children with systemic juvenile idiopathic arthritis

  18. Possession of the functional and non-functional KIR2DS4 isoforms in the mother and the fetus determines the risk of the vertical HIV-1 transmission.

  19. Data indicate that positive linkage disequilibrium was observed between KIR3DL1, 2DL1, 2DL3 and 2DS4 which is consistent with the associations between the constituents of A haplotypes.

  20. Our data revealed a unique contribution of activating KIRs (KIR2DS4, KIR2DS2, or KIR3DS1), in addition to NKG2C, in the expansion of human natural killer cells.

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4) Antigen-Profil

Protein Überblick

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Genbezeichner und Symbole assoziert mit KIR2DS4

  • killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (KIR2DS4) Antikörper
  • CD158I Antikörper
  • KIR1D Antikörper
  • KIR412 Antikörper
  • KKA3 Antikörper
  • NKAT8 Antikörper

Bezeichner auf Proteinebene für KIR2DS4

CD158 antigen-like family member I , KIR antigen 2DS4 , MHC class I NK cell receptor , NKAT-8 , P58 natural killer cell receptor clones CL-39/CL-17 , killer cell immunoglobulin-like receptor 2DS4 , killer inhibitory receptor 4-1-2 , natural killer cell inhibitory receptor , natural killer-associated transcript 8 , p58 NK receptor CL-39/CL-17

GENE ID SPEZIES
3809 Homo sapiens
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