anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) Antikörper

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Zusätzlich bieten wir Ihnen KIR2DL2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KIR2DL2 3803 P43627
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Top anti-KIR2DL2 Antikörper auf

Showing 10 out of 45 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD158b1 expression in MDAMB231 (A), Jurkat (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL 13 bis 14 Tage
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of KIR2DL2 using NIH-3T3 whole cell lysates 100 μL 11 bis 12 Tage
Human Kaninchen Unkonjugiert ICC, IHC, WB DAB staining on IHC-P; Samples: Human Bile duct cancer Tissue 100 μg 13 bis 16 Tage
Human Kaninchen Unkonjugiert FACS, WB Western blot analysis in MDA-MB231,Jurkat cell line lysates (35ug/lane). Flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL 2 bis 3 Tage
Human Maus Unkonjugiert FACS, IP   200 μg 11 bis 14 Tage
Human Kaninchen Unkonjugiert WB   100 μL 11 bis 14 Tage
Human Kaninchen Biotin WB   100 μL 11 bis 14 Tage
Human Kaninchen FITC WB   100 μL 11 bis 14 Tage
Human Kaninchen Unkonjugiert WB   100 μL 11 bis 14 Tage
Human Kaninchen Unkonjugiert FACS, WB   50 μg 11 bis 14 Tage

Weitere Antikörper gegen KIR2DL2 Interaktionspartner

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) Interaktionspartner

  1. Our finding suggests that presentation of specific LASV epitopes by HLA-C alleles to the inhibitory KIR2DL2 receptor on NK cells could potentially prevent the killing of infected cells and provides insights into the mechanisms by which LASV can escape NK-cell-mediated immune pressure.

  2. The multivariate analysis revealed that the lack of KIR2DS2 (p = 0.035), the presence of KIR2DL3 (p = 0.075), and the presence of KIR2DL2HLA-C1 (p = 0.044) were risk factors for posttransplant cytomegalovirus infection.

  3. The results suggest that KIR2DL2 and 2DS4del could have a risk role in the development of Systemic Sclerosis, but not with clinical manifestations.

  4. Killer cell immunoglobulin like receptor two (KIR2DL2) shows a risk association with Chinese Han hepatitis C virus-1b (HCV-1b) patients not responding to the combination therapy of pegylated alpha interferon (PEG-IFN) with ribavirin (RBV).

  5. KIR2DL2/HLA-C( *)12:02 and KIR2DL2/HLA-C( *)14:03 compound genotypes have protective effects on control of HIV-1.

  6. KIR2DL2 gene polymorphism is associated with HIV-1 infection.

  7. association between KIR2DS2 and the response to methotrexate (MTX), moreover, the combination KIR2DL2+/KIR2DS2+ was more frequent in responders to MTX (p = 0.043).

  8. KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.

  9. KIR2DL2/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children

  10. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2, KIR2DS4, KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  11. Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.

  12. a significant increase in the frequency of KIR2DL2 (P = 0.019) as well as KIR2DS2 (P = 0.008) in patients with neuroblastoma compared with the healthy control group, was found.

  13. Single Nucleotide Polymorphism in KIR2DL2 gene is associated with Asthma and Atopic Dermatitis.

  14. genetic polymorphism is associated with chronic hepatitis C and levels of viremia in Poland

  15. KIR2DL2 and KIR2DS2 genotype is associated with protection against primary biliary cirrhosis in Han population.

  16. Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.

  17. Authors showed an increase in HLA-C1/KIR2DL2 and HLA-C1/KIR2DL3 pairs in human papillomavirus high-risk infected patients (OR 3.05, 3.24) with invasive cervical cancer (OR 1.33, 3.68).

  18. KIR2DL3-positive NK cells were more sensitive to changes in the peptide content of MHC class I than KIR2DL2-positive NK cells.

  19. Authors showed a significant increased correlation between KIR2DL2/DS2, type 2 diabetes and HLA-C1C1 genotype in the type 2 diabetes patients infected with human herpesvirus 8.

  20. these results suggest that inhibitory KIR2DL2 and KIR2DL3, which are alleles of the same locus, play a role in the inverse effects on PM and PM/HIV co-infection

KIR2DL2 Antigen-Profil

Protein Überblick

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Genbezeichner und Symbole assoziert mit KIR2DL2

  • killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2) Antikörper
  • CD158b Antikörper
  • CD158B1 Antikörper
  • NKAT6 Antikörper
  • p58.2 Antikörper

Bezeichner auf Proteinebene für KIR2DL2

CD158 antigen-like family member B1 , MHC class I NK cell receptor , NKAT-6 , killer cell immunoglobulin-like receptor 2DL2 , natural killer-associated transcript 6 , p58 NK receptor CL-43 , p58 natural killer cell receptor clone CL-43

3803 Homo sapiens
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