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The protein encoded by KRT3 is a member of the keratin gene family. Zusätzlich bieten wir Ihnen Keratin 3 Antikörper (35) und viele weitere Produktgruppen zu diesem Protein an.
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Loss of normal CKB (zeige CHKB Proteine) structure and function contributes to the mechanisms by which isoaspartate accumulation leads to central nervous system dysfunction in the PIMT (zeige PCMT1 Proteine)-Knockout mouse.
CKB (zeige CHKB Proteine) plays a key role in myotube formation by limiting myoblast fusion during myogenesis.
BCK (zeige CKB Proteine) phosphorylation at Ser6 did not affect its enzymatic activity, but led to the appearance of the phosphorylated enzyme at the endoplasmic reticulum (ER)
Hypothalamic plasticity of neuropeptide Y (zeige NPY Proteine) is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation
negative regulation of CKB (zeige CHKB Proteine) by mHTT is a key event in the pathogenesis of HD and contributes to the neuronal dysfunction associated with HD.
reduced expression of brain creatine kinase (zeige CKB Proteine) in the cochlea of Huntington disease (zeige HTT Proteine) mice is associated with hearing impairment
In rat cerebrum and cerebellum, as in rat heart, at all ages the several cCK (zeige CCK Proteine) isoenzymes do participate in a gender-specific manner, in favor of females, in diverse functions of the different cell compartments of glial and neuronal cells.
cytoskeletal dynamics during cell motility is coupled to on-site availability of ATP generated by CKB (zeige CHKB Proteine)
we show that the two PAX6 (zeige PAX6 Proteine) isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12 (zeige KRT12 Proteine)). PAX6 (zeige PAX6 Proteine) isoform-a induced KRT3 expression by targeting its upstream region. KLF4 (zeige KLF4 Proteine) enhanced this induction. A combination of PAX6 (zeige PAX6 Proteine) isoform-b, KLF4 (zeige KLF4 Proteine), and OCT4 (zeige POU5F1 Proteine) induced KRT12 (zeige KRT12 Proteine) expression
Exon sequencing of KRT3 and KRT12 (zeige KRT12 Proteine) in six affected and eight unaffected individuals did not detect any mutations or nucleotide sequence variants in Meesmann epithelial corneal dystrophy.
A novel missense mutation (R503P) in KRT3 leads to MCD in 2 unrelated Taiwanese families.
Location of the E498V mutation emphasizes the functional relevance of the highly conserved boundary motifs at the COOH-terminus of the alpha-helical rod domain in keratin 3 (K3).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
, cytokeratin Ib (human cytokeratin 3)
, creatine kinase B chain
, creatine kinase B-type
, 65 kDa cytokeratin
, cytokeratin 3
, keratin, type II cytoskeletal 3
, type-II keratin Kb3
, K3 keratin
, Type-II keratin Kb3
, keratin K3