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The protein encoded by KRT23 is a member of the keratin family. Zusätzlich bieten wir Ihnen Keratin 23 Proteine (6) und Keratin 23 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal KRT23 Primary Antibody für IF, IHC (p) - ABIN565210
Aleskandarany, Soria, Green, Nolan, Diez-Rodriguez, Ellis, Rakha: Markers of progression in early-stage invasive breast cancer: a predictive immunohistochemical panel algorithm for distant recurrence risk stratification. in Breast cancer research and treatment 2015
Data show that Keratin23 (KRT23) knockdown affected molecules of the cell cycle and DNA replication, recombination and repair.
Increased expression of KRT23 is associated with colorectal cancer.
Data suggest a regulatory circuitry involving Smad4 dependent up-regulation of KRT23 (directly or indirectly) which in turn modulates the interaction between KRT23 and 14-3-3epsilon leading to a cytoplasmic sequestration of 14-3-3epsilon.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
, keratin complex 1, acidic, gene 23
, keratin, type I cytoskeletal 23
, type I intermediate filament cytokeratin
, cytokeratin 23
, histone deacetylase inducible keratin 23
, hyperacetylation-inducible type I keratin