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The protein encoded by KRT19 is a member of the keratin family. Zusätzlich bieten wir Ihnen Keratin 19 Antikörper (928) und Keratin 19 Proteine (30) und viele weitere Produktgruppen zu diesem Protein an.
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Aberrant decreased miR (zeige MLXIP ELISA Kits)-26a could promote cell proliferation by regulating KRT19 which plays important role in the pathogenesis of cholangiocarcinoma.
The detection of TK1 (zeige TK1 ELISA Kits) combined with that of cytokeratin-19 fragment (CYFRA21-1), CEA (zeige CEACAM5 ELISA Kits) or NSE (zeige ENO2 ELISA Kits) increased the diagnostic value of TK1 (zeige TK1 ELISA Kits) for lung squamous cell carcinoma, adenocarcinoma and small cell lung cancer, respectively.
Our results are of special importance against the background that CK19 positive carcinomas revealed a significantly poorer prognosis and therefore emphasize its prognostic and possible diagnostic role in tongue cancer.
(18)F-FDG (zeige SMUG1 ELISA Kits)-PET can be used to predict K19 expression in hepatocellular carcinoma and should thereby aid in the development of novel therapeutic strategies targeting K19(+) hepatocellular carcinoma cancer stem cells
Immunohistochemical assessment of both CK19 and SCCAg status in histologically negative sentinel lymph nodes may be a valuable approach for predicting recurrence and survival after curative surgery for cervical squamous cell carcinoma.
Positive CK-19 expression can be used as a predictor of poor prognosis of PNET
Data suggest that high cytokeratin 19 (CK19) levels in peripheral blood may independently predict non-sentinel lymph node (nSLN) metastasis in breast cancer patients.
Findings provide evidence that K19 expression is inducible in human hepatocellular carcinoma as a sign of tumor progression.
Urine levels of COL4A1 (zeige COL4A1 ELISA Kits), COL13A1 (zeige COL13A1 ELISA Kits), the combined values of COL4A1 (zeige COL4A1 ELISA Kits) and COL13A1 (zeige COL13A1 ELISA Kits) (COL4A1 (zeige COL4A1 ELISA Kits) + COL13A1 (zeige COL13A1 ELISA Kits)), and CYFRA21-1 were significantly elevated in urine from patients with BCa (zeige BLNK ELISA Kits) compared to the controls. A high urinary COL4A1 (zeige COL4A1 ELISA Kits) + COL13A1 (zeige COL13A1 ELISA Kits) was found to be an independent risk factor for intravesical recurrence.
CK19 and carcinoembryonic antigen (zeige CEACAM5 ELISA Kits) may be involved in lymph node metastasis and poor prognosis in patients with gastriccardia cancer
Cytokeratin-19 (CK-19)+ specific deletion of tumor suppressors p53 (zeige TP53 ELISA Kits) and Retinoblastoma (Rb) indicated that carcinomas at the injury site originates from cholangiocytes or liver progenitor cells.
Demonstrate that K19 plays an important role in the ductular reaction that constitutes the basic regenerative response to chronic liver injury.
Branched desmin (zeige DES ELISA Kits)-deficient (DKO) myofibers show significantly faster rates of calcium ion (Ca2 (zeige CA2 ELISA Kits)+) clearance, with milder branching phenotype observed in DKO muscle suggesting that absence of keratin-19 corrects the defect created by absence of desmin (zeige DES ELISA Kits) alone.
the structural response of each genotype is distinct, suggesting multiple mechanisms by which desmin and keratin influence the biomechanical properties of myofibers
The expression of CK19 and EGFR (zeige EGFR ELISA Kits) in lymphatic metastasis of laryngeal carcinoma was higher than in controls.
Results suggest that keratin filaments containing K19- and desmin (zeige DES ELISA Kits)-based intermediate filaments can play independent, complementary, or antagonistic roles in the physiology and morphology of fast-twitch skeletal muscle.
a dual mechanism of how PDX-1 (zeige PDX1 ELISA Kits) negatively regulates Krt19 ductal specific gene expression
expression of nestin (zeige NES ELISA Kits) and cytokeratin 19 is a normal property of embryonic stem cells preceding differentiation into C-peptide/insulin (zeige INS ELISA Kits)-producing cells without any selection for nestin (zeige NES ELISA Kits)-positive phenotypes
loss of the keratin cytoskeleton causes defects in the trophoblast giant cell layer
transduction of PDX1 (zeige PDX1 ELISA Kits) in primary pancreatic ductal cells suppresses K19 expression, and short interfering RNA to PDX1 (zeige PDX1 ELISA Kits) in Min6 insulinoma (zeige RPS15 ELISA Kits) cells and results in the induction of normally undetectable K19
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
40-kDa keratin intermediate filament
, cytokeratin 19
, keratin, type I cytoskeletal 19
, keratin, type I, 40-kd
, keratin complex 1, acidic, gene 19
, type I keratin KA19
, keratin 19
, Keratin, type I cytoskeletal 19
, keratin, type I cytoskeletal 19-like
, keratin 19, type I