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The protein encoded by KAT6B is a histone acetyltransferase and component of the MOZ/MORF protein complex. Zusätzlich bieten wir Ihnen KAT6B Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal KAT6B Primary Antibody für WB - ABIN2780878
Utley, C�té: The MYST family of histone acetyltransferases. in Current topics in microbiology and immunology 2003
KAT6B mutation is associated with Craniosynostosis.
chronic inflammation compromises unfolded protein response function through MORF-mediated-PERK transcription.
With ptosis, hypotonia, and developmental delay as the main diagnostic features of our patient, the effect of histone acetyltransferase (zeige HAT Antikörper)-encoding KAT6B gene haploinsufficiency was suspected to have a significant role in determining the phenotype.
Study identified the double plant homeodomain finger (DPF) of the lysine acetyltransferase MORF as a reader of global histone H3K14 acylation.
Our findings support that phenotypes associated with typical KAT6B disease-causing variants should be referred to as 'KAT6B spectrum disorders' or 'KAT6B related disorders', rather than their current SBBYSS and GTPTS classification
Studies show that misregulation of MOZ (zeige MYST3 Antikörper)/MORF results in tumorigenesis and developmental disorders. Results also provide evidence that these 2 proteins play important role in regulating cell proliferation and stem cell maintenance. [review]
KAT6B sequence variants are being reported in the Say-Barber-Biesecker type of blepharophimosis mental retardation syndromes (SBBS) and in the more severe genitopatellar syndrome.
This study shown MYST4 to be the risk factor for attention deficit/hyperactivity disorder.
Homozygous deletions of KAT6B and the loss of its mRNA occur in SCLC cell lines and primary tumors. KAT6B loss enhances cancer growth. Restoration induces tumor suppressor-like features involving a new type of histone H3 Lys23 acetyltransferase activity.
The relationship between MYO1C (zeige MYO1C Antikörper) and KAT6B suggests that the two are interacting in chromatin remodelling for gene expression in human masseter muscle. This is the nuclear myosin1 (zeige DNAH8 Antikörper) (NM1 (zeige MYO1C Antikörper)) function of MYO1C (zeige MYO1C Antikörper).
MYST4 may contribute to important and specific acetylation events occurring during gametes and embryo development
Data indicate that Myst4, Jmjd2b (zeige KDM4B Antikörper), Aof1 (zeige KDM1B Antikörper) genes are regulated by H3K9me under hyperinsulinemia/hyperglycemia.
Data show that H3 acetylation by Myst4 is important for neural, craniofacial, and skeletal morphogenesis, mainly through its ability to specifically regulating the MAPK (zeige MAPK1 Antikörper) signaling pathway.
Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase (zeige HAT Antikörper) and deacetylase activities in murine skin and tumors.
MORF4 (zeige MORF4 Antikörper) has a role in cellular aging, and MRG15 (zeige MORF4L1 Antikörper) associates with both histone deacetylases and histone acetyl transferase (zeige HAT1 Antikörper) complexes [review]
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
histone acetyltransferase MYST4
, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4
, MOZ-related factor
, MYST histone acetyltransferase (monocytic leukemia) 4
, histone acetyltransferase KAT6B
, histone acetyltransferase MORF
, histone acetyltransferase MOZ2
, monocytic leukemia zinc finger protein-related factor
, MYST histone acetyltransferase monocytic leukemia 4
, histone acetyltransferase querkopf
, monocytic leukemia
, protein querkopf