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The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. Zusätzlich bieten wir Ihnen Jun D Proto-Oncogene Antikörper (161) und Jun D Proto-Oncogene Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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identify AP-1(JunD/c-Fos) as a novel hematopoietic transcription factor and the requirement of AP-1(JunD/c-Fos) in BMP-4 (zeige BMP4 ELISA Kits)-induced hematopoiesis during Xenopus hematopoiesis.
Data indicate the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and suggest structural insight for therapeutic interventions targeting AP-1 proteins.
In T cells, after serum deprivation HBZ induces the expression of Delta JunD isoform. Unlike JunD, Delta JunD induces proliferation and transformation of cells. HBZ bypasses translational control of JunD uORF and favors the expression of Delta JunD. The truncated isoform Delta JunD has a central role in the oncogenic process leading to adult T-cell leukemia .
MiR (zeige MLXIP ELISA Kits)-663a suppresses proliferation and invasion by targeting AP-1 (zeige FOSB ELISA Kits) component JunD in non-small cell lung cancer cells.
studies showed that down-regulation of JunD in response to TGF-beta (zeige TGFB1 ELISA Kits) treatment is mediated via the proteasomal degradation pathway.
CARMA1- and MyD88 (zeige MYD88 ELISA Kits)-dependent activation of Jun (zeige JUN ELISA Kits)/ATF-type AP-1 (zeige FOSB ELISA Kits) complexes is a hallmark of ABC (zeige ABCB6 ELISA Kits) diffuse large B-cell lymphomas.
recombinant SERPINE2 (zeige SERPINE2 ELISA Kits) induced a clear inhibition of MMP-13 (zeige MMP13 ELISA Kits) expression in IL-1alpha-stimulated chondrocytes. This inhibitory effect is likely regulated through a pathway involving ERK 1 (zeige MAPK3 ELISA Kits)/2, NF-kappaB (zeige NFKB1 ELISA Kits) and AP-1 (zeige FOSB ELISA Kits)
miR (zeige MLXIP ELISA Kits)-494 is a novel regulator of HNPC apoptosis induced by TNF-alpha (zeige TNF ELISA Kits)
JunD activates miR (zeige MLXIP ELISA Kits)-29b by enhancing its transcription and processing, which contribute to the inhibitory effect of JunD
Binding of specific AP-1 (zeige FOSB ELISA Kits) factors, we found JunD associated with the LILRB1 (zeige LILRB1 ELISA Kits) distal promoter.
Cells in contact with basement membrane undergo transient oscillations between two molecular states defined by their TGFBR3 (zeige TGFBR3 ELISA Kits)- JUND expression.
The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 (zeige JUN ELISA Kits) DNA-binding activity and expression of several transcriptions factors in breast cancer cells.
Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells.
JunD provides protection in aging-induced endothelial dysfunction and may represent a novel target to prevent reactive oxygen species-driven vascular aging.
AP-1 (zeige JUN ELISA Kits) composed with JunD and Fra2 (zeige FOSL2 ELISA Kits) protein plays a primary role in enhancing the transcription level of the CD11c (zeige ITGAX ELISA Kits) gene in dendritic cells
Nfe2 modulates JunD binding to the Gcm1 promoter via acetylation
5-HT2B (zeige HTR2B ELISA Kits) blockade enhances liver regeneration by inhibiting induction of TGF-beta1 (zeige TGFB1 ELISA Kits) expression by hepatic stellate cells that is dependent on 5-HT (zeige DDC ELISA Kits), ERK (zeige EPHB2 ELISA Kits) and JunD.
CDK4 (zeige CDK4 ELISA Kits)-mediated regulation of cell functions via c-Jun (zeige JUN ELISA Kits) phosphorylation and AP-1 (zeige JUN ELISA Kits) activation
Downregulation of JunD and cyclin D1 (zeige CCND1 ELISA Kits) expression in myofibroblasts may be important regarding the mechanism of action of MTA (zeige DNMT1 ELISA Kits) in Mdr2 (zeige ABCB4 ELISA Kits)-/- mice
c-Jun (zeige JUN ELISA Kits), JunB (zeige JUNB ELISA Kits), and JunD are not functionally equivalent and have both overlapping and independent functions in controlling cellular proliferation, cell-cycle arrest/senescence and the response to stress.
Study supports potential roles for jun (zeige JUN ELISA Kits) D, jun (zeige JUN ELISA Kits) B, and fra-1 (zeige FOSL1 ELISA Kits) in the dietary energy restriction regulation of AP-1 (zeige JUN ELISA Kits) function in the Sencar mouse skin carcinogenesis model.
protects cells from p53 (zeige TP53 ELISA Kits)-dependent senescence and apoptosis
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
transcription factor jun-D
, JunD-FL isoform
, activator protein 1
, Jun proto-oncogene related gene d1