Jumonji Domain Containing 6 (JMJD6) ELISA Kits

JMJD6 encodes a nuclear protein with a JmjC domain. Zusätzlich bieten wir Ihnen Jumonji Domain Containing 6 Antikörper (126) und Jumonji Domain Containing 6 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
JMJD6 360665 Q6AYK2
JMJD6 23210 Q6NYC1
JMJD6 107817 Q9ERI5
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Top Jumonji Domain Containing 6 ELISA Kits auf antikoerper-online.de

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Human
  96 Tests 11 bis 18 Tage
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Weitere ELISA Kits für Jumonji Domain Containing 6 Interaktionspartner

Human Jumonji Domain Containing 6 (JMJD6) Interaktionspartner

  1. Inhibiting CDK4 abolished the ability of JMJD6 in enhancing cell proliferation.

  2. knockdown of JMJD6 reduces the proliferation, migration and invasion of neuroglioma stem cells

  3. The JMJD6-H2A.X(Y39ph) axis promoted triple negative breast cance cell growth via the autophagy pathway.

  4. results indicate for the first time that JMJD6 plays an important role in the regulation of ADSCs proliferation and migration through the modulation of PDE1C expression.

  5. Consistent with its role in transcriptional activation, JMJD6 is required for estrogen/ERalpha-induced breast cancer cell growth and tumorigenesis, via modulation of recruitment of CARM1/MED12 co-activator complex.

  6. JMJD6 is a novel Stress Granule component that interacts with G3BP1 complexes, and its expression reduces G3BP1 monomethylation and asymmetric dimethylation at three Arg residues.

  7. JMJD6 regulates VHL gene expression in the human placenta. VHL downregulation in preeclampsia is dependent on decreased JMJD6 demethylase activity due to hypoxia and reduced Fe2+ bioavailability.

  8. In tumor samples but not normal breast tissue, the expression of JMJD6 linearly correlated with HOTAIR suggesting that JMJD6-mediated up-regulation may occur specifically in tumors.

  9. Results show that JMJD6 is up-regulated in melanoma, and high expression of JMJD6 protein is strongly correlated with advanced stages and aggressiveness of melanoma. It enhances the MAPK signaling through regulation of alternative splicing of PAK1 promoting multiple cellular processes including melanogenesis, proliferation, invasion, and angiogenesis in melanoma cells.

  10. High JMJD6 expression is associated with Neuroblastomas.

  11. miR-770 acted on a tumor suppressor by binding to the 3'UTR of JMJD6 and downregulated its expression in NSCLC cells; this study also demonstrated that JMJD6 played as an oncogene in NSCLC cells

  12. JMJD6 regulated a large set of alternative splicing events, and importantly, its regulated splicing events were significantly overlapped those controlled by U2AF65.

  13. AcK27-HOXB9 suppresses the transcription of its target gene Jumonji domain-containing protein 6 (JMJD6) by direct occupying the promoter of JMJD6 gene.

  14. These findings provide evidence that JMJD6 may play a role in regulating the production of sFLT-1 in the preeclamptic placenta. Decreased placental JMJD6 expression may be an important component to the pathophysiology of preeclampsia.

  15. Study identified a novel epigenetic mechanism showing how JMJD6 cooperates with Myc during oncogenic transformation. Combined high expression of Myc and JMJD6 confers a more aggressive phenotype in mouse and human tumors.

  16. Our studies identify JMJD6 as a molecular determinant of cancer stem cell phenotype

  17. Although JMJD6 displays anti-tumoral properties in cell lines, its expression in breast tumours may be a marker of poor prognosis, suggesting that its function could be altered in breast cancer

  18. The expression of JMJD6 was reduced in T lymphocytes in chronic hepatitis B.

  19. A novel role for JMJD6 as an oxygen sensor in the human placenta, and alterations in the JMJD6-VHL-HIF1A feedback loop may indirectly contribute to elevated HIF1A found in preeclampsia.

  20. JMJD6 is a potential biomarker for colon cancer aggressiveness and a potential target for colon cancer intervention.

Zebrafish Jumonji Domain Containing 6 (JMJD6) Interaktionspartner

  1. results suggest that YY1a regulates PS receptor expression that linked to function of PSR-phagocyte mediated apoptotic cell engulfment during development

  2. PSR-dependent system in zebrafish embryos that engulfs apoptotic cells mediated by PSR-phagocytes during development, with the system assuming an important role in the normal development of tissues such as the brain, heart, notochord and somite

Mouse (Murine) Jumonji Domain Containing 6 (JMJD6) Interaktionspartner

  1. TEC-specific deletion of Jmjd6 exacerbates development of autoimmune diabetes in a mouse model, which express both ovalbumin (OVA) under the control of the rat insulin gene promoter and OT-I T cell receptor specific for OVA peptide bound to major histocompatibility complex class I K(b) molecules.

  2. Although Jmjd6 deficiency does not affect abundance of Aire transcript, the intron 2 of Aire gene is not effectively spliced out in the absence of Jmjd6, resulting in reduction of mature Aire protein and spontaneous multi-organ autoimmunity in mice.

  3. The results indicate dual roles for JMJD6 in promoting adipogenic gene expression program by post-transcriptional regulation of C/EBPbeta and C/EBPdelta and direct transcriptional activation of Ppargamma2 and Cebpalpha during adipocyte differentiation.

  4. histones are additional substrates of JMJD6 in vivo. Because 5-hydroxylation of lysyl residues inhibited N-acetylation and N-methylation by an acetyltransferase and a methyltransferase

  5. confirmed that Jmjd6 forms multimers and showed that nuclear localization of the protein involves association with a nucleic acid matrix

  6. protein kinase C beta activation is dependent upon phosphatidylserine receptor action

  7. data demonstrate a critical role for PSR in early stages of mammalian organogenesis and suggest that this receptor may be involved in respiratory distress syndromes and congenital brain malformations

  8. during embryonic development, phosphatidylserine receptor-mediated apoptotic cell uptake is required for definitive erythropoiesis and T lymphopoiesis, independently of the prevention of inflammatory responses

  9. Ptdsr is localized in the cell nucleus via multiple nuclear localization signals.

  10. Ptdsr is essential for the development and differentiation of multiple organs during embryogenesis but not for apoptotic cell clearance.

  11. identified cardiac malformations in Ptdsr deficient embryos, including ventricular septal defects, double-outlet right ventricle, and hypoplasia of the pulmonary artery and thymus.

  12. Results suggest that the presumptive phosphatidylserine receptor is not involved generally in either specific innate recognition or engulfment of apoptotic cells.

Cow (Bovine) Jumonji Domain Containing 6 (JMJD6) Interaktionspartner

  1. JMJD6 contributes to foot-and-mouth disease virus infectivity and may be a previously unidentified foot-and-mouth disease receptor.

  2. Demethylated RHA bound JMJD6 monomer during foot-and-mouth disease virus infection.

Jumonji Domain Containing 6 (JMJD6) Antigen-Profil

Beschreibung des Gens

This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells\; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit JMJD6

  • arginine demethylase and lysine hydroxylase (Jmjd6) Antikörper
  • arginine demethylase and lysine hydroxylase (JMJD6) Antikörper
  • jumonji domain containing 6 (jmjd6) Antikörper
  • jumonji domain containing 6 (Jmjd6) Antikörper
  • bifunctional arginine demethylase and lysyl-hydroxylase PSR (LOC411069) Antikörper
  • jumonji domain containing 6 (JMJD6) Antikörper
  • jmjC domain-containing protein 4 homolog (LOC5577546) Antikörper
  • phosphatidylserine receptor (CpipJ_CPIJ004848) Antikörper
  • phosphatidylserine receptor (CpipJ_CPIJ019866) Antikörper
  • jumonji domain containing 6 S homeolog (jmjd6.S) Antikörper
  • jumonji domain containing 6 L homeolog (jmjd6.L) Antikörper
  • 5730436I23Rik Antikörper
  • cg5383 Antikörper
  • D11Ertd195e Antikörper
  • GB15204 Antikörper
  • jmjd6 Antikörper
  • mKIAA0585 Antikörper
  • psr Antikörper
  • PtdSerR Antikörper
  • ptdsr Antikörper
  • ptdsr1 Antikörper
  • zfpsr Antikörper
  • zgc:66264 Antikörper

Bezeichner auf Proteinebene für JMJD6

bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 , histone arginine demethylase JMJD6 , jmjC domain-containing protein 6 , jumonji domain-containing protein 6 , lysyl-hydroxylase JMJD6 , peptide-lysine 5-dioxygenase JMJD6 , phosphatidylserine receptor , jumonji domain containing 6 , apoptotic cell clearance receptor PtdSerR , protein PTDSR , Histone arginine demethylase JMJD6 , bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B , histone arginine demethylase JMJD6-B , jmjC domain-containing protein 6-B , jumonji domain-containing protein 6-B , lysyl-hydroxylase JMJD6-B , peptide-lysine 5-dioxygenase JMJD6-B , phosphatidylserine receptor-B , protein PTDSR-B , bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A , histone arginine demethylase JMJD6-A , jmjC domain-containing protein 6-A , jumonji domain-containing protein 6-A , lysyl-hydroxylase JMJD6-A , peptide-lysine 5-dioxygenase JMJD6-A , phosphatidylserine receptor-A , protein PTDSR-A

GENE ID SPEZIES
360665 Rattus norvegicus
23210 Homo sapiens
266962 Danio rerio
100230335 Taeniopygia guttata
107817 Mus musculus
411069 Apis mellifera
417355 Gallus gallus
508343 Bos taurus
5577546 Aedes aegypti
6036446 Culex quinquefasciatus
6054124 Culex quinquefasciatus
468338 Pan troglodytes
548957 Xenopus (Silurana) tropicalis
100173544 Pongo abelii
380206 Xenopus laevis
444377 Xenopus laevis
483335 Canis lupus familiaris
100722696 Cavia porcellus
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