Interleukin 27 Proteine (IL27)

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Zusätzlich bieten wir Ihnen IL27 Antikörper (166) und IL27 Kits (53) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IL27 246778 Q8NEV9
IL27 365368  
IL27 246779 Q8K3I6
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Top IL27 Proteine auf

Showing 10 out of 22 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
CHO Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
Human Cells Maus His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Maus Unkonjugiert   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
HEK-293 Cells Human Unkonjugiert   10 μg Anmelden zum Anzeigen 3 bis 4 Tage
CHO Cells Human Unkonjugiert   100 μg Anmelden zum Anzeigen 3 bis 4 Tage

IL27 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
Rat (Rattus)

Mouse (Murine) , ,

Am meisten referenzierte IL27 Proteine

  1. Human IL27 Protein expressed in Wheat germ - ABIN1307800 : Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 2 Pubmed References

Weitere Proteine zu Interleukin 27 (IL27) Interaktionspartnern

Human Interleukin 27 (IL27) Interaktionspartner

  1. This study failed to find an association between common variants in the functional region of IL27 and coronary artery disease in a Chinese Han population

  2. Data point out to a broad set of activities shared by IL-27 and IFN-gamma (zeige IFNG Proteine), which are dependent on the common activation of the STAT1 (zeige STAT1 Proteine) pathway. These data add further explanation to the anti-tumor activity of IL-27 and also to its dual role in immune regulation

  3. The current meta-analysis suggests that IL-27 -964A/G polymorphism might enhance cancer risk. However, large-scale and well-designed studies are still needed to confirm the result of our meta-analysis

  4. this study found elevated expression of IL-27 in human peripheral serum and elevated expression of its specific receptor (wsx-1 (zeige IL27RA Proteine)) on fetal membranes in cases of preterm birth

  5. results indicate that elevated IL-27 strongly correlates with EOS (zeige IKZF4 Proteine) and may provide additional diagnostic value along with PCT (zeige UROD Proteine).

  6. serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barre syndrome

  7. Expression of IL-27 in the serum was markedly increased in patients with sepsis-induced myo (zeige IRF6 Proteine)cardial dysfunction compared with that in controls.

  8. IL-27 significantly inhibited the M2 macrophages polarization and dampened the proliferation, migration and metastasis of pancreatic cancer cells and as well enhanced the efficacy of gemcitabine.

  9. IL-27 increased NLRP3 (zeige NLRP3 Proteine) inflammasome activation in monocytes with enhanced release of IL-1 beta (zeige IL1B Proteine).

  10. this study shows that interleukin 27 is up-regulated in patients with active inflammatory bowel disease

Mouse (Murine) Interleukin 27 (IL27) Interaktionspartner

  1. TTP (zeige ZFP36 Proteine), encoded by Zfp36 (zeige ZFP36 Proteine), degrades p28 (zeige GSTO1 Proteine) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.

  2. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (zeige TXNRD1 Proteine)-like cells in celiac disease

  3. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (zeige TP53 Proteine) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  4. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (zeige LTF Proteine).

  5. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (zeige TLR4 Proteine) injection compared with control specimens.

  6. these findings highlight critical roles for IFN-gamma (zeige IFNG Proteine) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

  7. IL-27-induced Sca-1(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes (zeige EOMES Proteine) and Blimp1 (zeige PRDM1 Proteine).

  8. found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 (zeige IL6 Proteine) is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27

  9. We demonstrate that IL-27-deficiency is linked to increased mucosal presence of ILC2 in a model of inflammatory lung disease. Moreover, IL-27-treatment inhibited ILC2 proliferation and cytokine production and significantly reduced their accumulation in vivo.

  10. These data suggest a novel role of the sympathetic neuroendocrine system for the modulation of IL-27-dependent acute inflammation.

Pig (Porcine) Interleukin 27 (IL27) Interaktionspartner

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Protein Überblick

Protein Überblick

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Genbezeichner und Symbole assoziert mit Interleukin 27 Proteine (IL27)

  • interleukin 27 (IL27)
  • interleukin 27 (Il27)
  • IL-27 Protein
  • IL-27A Protein
  • IL-27p28 Protein
  • IL27 Protein
  • IL27A Protein
  • IL27p28 Protein
  • Il30 Protein
  • p28 Protein
  • RGD1561420 Protein

Bezeichner auf Proteinebene für Interleukin 27 Proteine (IL27)

IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 , interleukin 27 p28 subunit , p28

246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100349321 Oryctolagus cuniculus
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
Ausgewählte Anbieter für IL27 Proteine (IL27)
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