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The protein encoded by IL1F10 is a member of the interleukin 1 cytokine family. Zusätzlich bieten wir Ihnen IL1F10 Antikörper (53) und IL1F10 Proteine (19) und viele weitere Produktgruppen zu diesem Protein an.
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Il-38-deficiency did not impact the development or resolution of Imiquimod-induced skin inflammation.
IL-38 overexpression attenuates the severity of experimental arthritis. IL-38 may exert its anti-inflammatory effects by decreasing the production of proinflammatory cytokines by macrophages and synovial fibroblasts.
IL-38 may play an important role in acute and/or chronic inflammation in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis.
IL-38 may exert its anti-inflammatory effects by decreasing the production of proinflammatory cytokines by macrophages and synovial fibroblasts.
this clinical study demonstrates the elevation of anti-inflammatory cytokine IL-38 and the decrement of CD4 (zeige CD4 ELISA Kits)+CD25highFoxP3+ and CD4 (zeige CD4 ELISA Kits)+CD25highCD127- Treg in childhood asthma. The negative correlation of IL-38 and Treg lymphocytes may imply a negative feedback of the two anti-inflammatory factors in asthma.
this study shows that in vivo expression of human IL-38 in mice has hepatoprotective effects against Con (zeige DISP1 ELISA Kits) A-induced liver injury by inhibition of inflammatory cytokine production
Higher serum IL-38 levels before treatment indicate a greater probability of viral response to telbivudine treatment in chronic hepatitis B.
results indicate that circulating IL-38 is a potentially novel biomarker for patients with ST-segment elevation myocardial infarction
Data suggest that IL-38 may be protective in SLE. A strong association between IL-38 and SLE severity suggests that IL-38 expression is driven by processes linked to SLE pathogenesis.
rs6759676, closest gene locus IL1F10 is associated with increased circulating levels of IL-1 (zeige IL1A ELISA Kits) receptor antagonist, a protective factor in development of insulin (zeige INS ELISA Kits) resistance.
The IL1A (zeige IL1A ELISA Kits) locus was strongly associated with alkylosing spondyloarthritis phenotype, whereas IL1F10 was associated with non-alkylosing spondyloarthritis.
These data provide evidence that IL-38 binds to the IL-36R (zeige IL1RL2 ELISA Kits), as does IL-36Ra.[IL-38, IL-36R (zeige IL1RL2 ELISA Kits)]
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.
, interleukin 1 family, member 7
, interleukin-1 family member 10
, FIL1 theta
, IL-1 theta
, IL-1F10 (canonical form IL-1F10a)
, interleukin-1 HY2
, interleukin-1 receptor antagonist FKSG75
, interleukin-1 receptor antagonist-like FIL1 theta