Interferon gamma Receptor 2 (Interferon gamma Transducer 1) Proteine (IFNGR2)

IFNGR2 (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Zusätzlich bieten wir Ihnen IFNGR2 Antikörper (125) und IFNGR2 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IFNGR2 15980  
Ratte IFNGR2 IFNGR2 360697  
IFNGR2 3460 P38484
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Top IFNGR2 Proteine auf

Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar

IFNGR2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, , ,

Weitere Proteine zu Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) Interaktionspartnern

Mouse (Murine) Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) Interaktionspartner

  1. Myeloid cell IFNGR2 deficiency does not affect atherosclerosis development in LDLR (zeige LDLR Proteine) knockout mice.

Human Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) Interaktionspartner

  1. The study identified an SNP rs9978223 on IFNGR2 gene, associated with increased risk in acute myocardial infarctionpatient from India.

  2. A crystal structure of the extracellular part of human interferon-gamma receptor 2 (IFNGR2) was solved by molecular replacement at 1.8 A resolution.

  3. Data suggest IFNG (zeige IFNG Proteine) plays various roles in dynamics of inflammation in subjects with underlying autoimmunity modeled as "canonical" and "non-canonical" pathways; in canonical pathway, IFNG (zeige IFNG Proteine) dimerizes and binds to IFNGR1 (zeige IFNGR1 Proteine) in IFNGR1 (zeige IFNGR1 Proteine)/IFNGR2 hetero-multimer; STAT (zeige STAT1 Proteine) transcription factors are involved in non-canonical pathway. (IFNG (zeige IFNG Proteine) = interferon gamma (zeige IFNG Proteine); IFNGR (zeige IFNGR1 Proteine) = IFNG (zeige IFNG Proteine) receptor; STAT (zeige STAT1 Proteine) = signal transducers and activators of transcription)

  4. IFN-gammaR2 T168N mutant diffusion is confined by distinct actin nanodomains where conformational changes required for JAK (zeige JAK3 Proteine)/STAT (zeige STAT1 Proteine) activation by IFN-gamma (zeige IFNG Proteine) could not occur. Removing IFN-gammaR2 T168N-bound galectins restored lateral diffusion in lipid nanodomains and JAK (zeige JAK3 Proteine)/STAT (zeige STAT1 Proteine) signaling in patient cells, whereas adding galectins impaired these processes in control cells.

  5. Statistical analyses revealed that four genetic variants in IFNGR1 (zeige IFNGR1 Proteine) were marginally associated with the risk of Tuberculosis (P = 0.02-0.04), while other single nucleotide polymorphisms in IFNGR1 (zeige IFNGR1 Proteine) and IFNGR2 did not exhibit any associations

  6. The variability of potentially important functional polymorphic variants of the IFNG (zeige IFNG Proteine), IFNGR2 and NEIL2 (zeige NEIL2 Proteine) genes was characterized in representatives of four ethnic groups living in the Siberian region.

  7. Fatal hemophagocytic lymphohistiocytosis has been described in two unrelated pediatric patients with underlying IFNGR2 deficiency.

  8. The expression of IFNGR2 was significantly higher in patients with RA compared with control subjects and was significantly higher in patients in whom radiographic damage was more severe.

  9. We report a molecular study of the two known patients with autosomal recessive, partial interferon-gamma (zeige IFNG Proteine) receptor (IFN-gammaR (zeige IFNGR1 Proteine))2 deficiency

  10. IFN-gammaR2-deficient monocytes induce a higher percentage of IL-17 (zeige IL17A Proteine)(+) cells from both healthy and IFN-gammaR2-deficient CD4 (zeige CD4 Proteine)(+) T cells.

Cow (Bovine) Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) Interaktionspartner

  1. Four SNPs in IFNGR2, IL12RB1 (zeige IL12RB1 Proteine), IL12RB2 (zeige IL12RB2 Proteine), and IL23R (zeige IL23R Proteine) were found to be associated with the MAP infection status of the resource population.

  2. SNPs in IFNG (zeige IFNG Proteine), IFNGR1 (zeige IFNGR1 Proteine) and R2, IL22 (zeige IL22 Proteine), and IL22RA1 (zeige IL22RA1 Proteine) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

IFNGR2 Protein Überblick

Protein Überblick

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

Genbezeichner und Symbole assoziert mit IFNGR2

  • interferon gamma receptor 2 (Ifngr2)
  • interferon gamma receptor 2 (IFNGR2)
  • interferon gamma receptor 2 (LOC487739)
  • AF-1 Protein
  • IFGR2 Protein
  • Ifgt Protein
  • IFNGT1 Protein

Bezeichner auf Proteinebene für IFNGR2

IFN-gamma receptor 2 , IFN-gamma-R2 , interferon gamma receptor 2 , interferon gamma receptor accessory factor 1 , interferon gamma receptor accessory factor-1 , interferon gamma receptor beta chain , interferon gamma transducer 1

15980 Mus musculus
360697 Rattus norvegicus
3460 Homo sapiens
487739 Canis lupus familiaris
514889 Bos taurus
Ausgewählte Anbieter für IFNGR2 Proteine (IFNGR2)
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