Interferon Stimulated Exonuclease Gene 20kDa Proteine (ISG20)

Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Zusätzlich bieten wir Ihnen ISG20 Antikörper (52) und ISG20 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte ISG20 ISG20 293052  
ISG20 3669 Q96AZ6
ISG20 57444 Q9JL16
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Top ISG20 Proteine auf

Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 bis 35 Tage
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Wheat germ Human GST tag 10 μg 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Hefe Human Unkonjugiert   100 μg 11 bis 16 Tage

ISG20 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu Interferon Stimulated Exonuclease Gene 20kDa (ISG20) Interaktionspartnern

Human Interferon Stimulated Exonuclease Gene 20kDa (ISG20) Interaktionspartner

  1. we have identified a novel mechanism involving ISG20 induction by T3 via the IL-8/p-JAK2/p-STAT3 signaling pathway to promote tumor angiogenesis in HCC.

  2. In conclusion, the authors identified that the influenza A virus-upregulated Long noncoding RNA lnc-ISG20 is a novel interferon-stimulated gene that elicits its inhibitory effect on influenza A virus replication by enhancing ISG20 expression. They demonstrated that lnc-ISG20 functions as a competitive endogenous RNA to bind miR-326 to reduce its inhibition of ISG20 translation.

  3. Interferon-stimulated gene of 20 kDa protein (ISG20) acts as an innate anti-HBV effector that selectively degrades hepatitis B virus (HBV) RNA and blocks replication of infectious HBV particles.

  4. Variation at rs12913965 may affect the risk for shoulder dislocation by affecting the activity of either TICRR or ISG20.

  5. We discovered two genome-wide significant SNPs. The first was novel and near ISG20. The second was in TRIOBP, a gene previously associated with prelingual nonsyndromic hearing loss. Motivated by our TRIOBP results, we also looked at exons in known hearing loss genes, and identified two additional SNPs, rs2877561 in ILDR1 and rs9493672 in EYA4 (at a significance threshold adjusted for number of SNPs in those regions).

  6. these data provide a detailed explanation for the specific antiviral action of ISG20 and suggest that ISG20 may act as a promising antiviral drug candidate against IAV.

  7. The results suggest that hantavirus infection interferes with DAXX-mediated apoptosis, and expression of interferon-activated Sp100 and ISG-20 proteins may indicate intracellular intrinsic antiviral attempts.

  8. ISG20 inhibited infections by hepatitis C virus, bovine viral diarrhea virus and hepatitis A virus. Moreover, ISG20 demonstrated cell-type specific antiviral activity against yellow fever virus, a classical flavivirus.

  9. ISG20has distinctive residues, Met14 and Arg53, to accommodate hydrogen bonds with the 2'-OH group of the UMP ribose, and these residues may be responsible for the preference of ISG20 for RNA substrates

  10. ISG20 has a role in reducing the synthesis of HBV proteins

Mouse (Murine) Interferon Stimulated Exonuclease Gene 20kDa (ISG20) Interaktionspartner

  1. ISG20 upregulated IFIT1 genes and inhibited translation of the alphavirus genome. Furthermore, IFIT1-sensitive alphavirus replication was increased in Isg20(-/-) mice compared to the replication of wild-type viruses but not in cells ectopically expressing ISG20.

  2. Suggest that the recruitment of peripheral CXCR4-expressing ITGA2(+)ISG20(+) NK cells into pregnant uteri may be important in the regulation of feto-maternal tolerance.

ISG20 Protein Überblick

Protein Überblick

Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. May be involved in the antiviral function of IFN against RNA viruses (By similarity). Besides its function in antiviral defense, ISG20 may play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis (By similarity).

Genbezeichner und Symbole assoziert mit ISG20

  • interferon stimulated exonuclease gene 20 (ISG20)
  • interferon stimulated exonuclease gene 20 (Isg20)
  • interferon-stimulated protein (Isg20)
  • 20kDa Protein
  • 1600023I01Rik Protein
  • 2010107M23Rik Protein
  • CD25 Protein
  • DnaQL Protein
  • HEM45 Protein
  • ISG20 Protein

Bezeichner auf Proteinebene für ISG20

interferon stimulated exonuclease gene 20kDa , interferon stimulated exonuclease 20 , interferon stimulated gene 20kDa , interferon-stimulated gene 20 kDa protein , interferon-stimulated protein , estrogen-regulated transcript 45 protein , promyelocytic leukemia nuclear body-associated protein ISG20 , interferon stimulated exonuclease

698376 Macaca mulatta
293052 Rattus norvegicus
3669 Homo sapiens
488729 Canis lupus familiaris
448855 Sus scrofa
506604 Bos taurus
57444 Mus musculus
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