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IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Zusätzlich bieten wir Ihnen IFITM2 Antikörper (47) und IFITM2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Delta20 IFITM2 may serve as a major contributor to the gatekeeping mechanism that explains restriction of X4 viruses in the early stage of HIV-1 infection
These results indicate that IFITM2 protein can restrict alphavirus infection by inhibiting viral fusion with cellular membranes.
The transcriptional regulation of IFITM1 (zeige IFITM1 Proteine), 2 and 3 expression.
IFITM2 promotes gastric cancer growth and metastasis via IGF1 (zeige IGF1 Proteine)/IGF1R (zeige IGF1R Proteine)/STAT3 (zeige STAT3 Proteine) signaling pathway.
findings show that the sensitivity of influenza A viruses to the IFN-induced antiviral state and IFITM2 and IFITM3 (zeige IFITM3 Proteine) proteins depends on the pH value at which the viral HA undergoes a conformational transition and mediates membrane fusion
IFITM2 and IFITM3 (zeige IFITM3 Proteine) specifically antagonize the HIV-1 envelope glycoprotein (Env (zeige ERVW-1 Proteine)), thereby inhibiting viral infection.
G3BP1 (zeige G3BP1 Proteine), G3BP2 (zeige G3BP2 Proteine) and CAPRIN1 are required for translation of interferon (zeige IFNA Proteine) stimulated mRNAs and are targeted by a dengue virus non-coding RNA.
Incorporation of IFITM1 (zeige IFITM1 Proteine), IFITM2 and IFITM3 (zeige IFITM3 Proteine) into HIV-1 virions impair viral fusion and spread.
Host IFITM3 (zeige IFITM3 Proteine),IFITM2 and IFITM1 (zeige IFITM1 Proteine) facilitate morphogenesis of the human cytomegalovirus assembly.
Although their inhibitory activities were modest when compared to that of tetherin (zeige BST2 Proteine), IFITMs, but not tetherin (zeige BST2 Proteine), directly reduced the expression of HIV-1 proteins including Gag, Vif (zeige BTG1 Proteine) and Nef.
IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
dispanin subfamily A member 2c
, interferon-induced transmembrane protein 2
, interferon-inducible protein 1-8D
, fragilis R
, fragilis protein 3
, interferon induced transmembrane protein, like
, interferon induced transmembrane protein 2 (1-8D)
, interferon-inducible protein 16