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IFNK encodes a member of the type I interferon family. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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Mouse IFN-kappa is expressed at low levels in peritoneal macrophages, its expression up-regulated by double-stranded RNA and IFN-gamma (zeige IFNG ELISA Kits); transgenic mice overexpressing murine IFN-kappa in the pancreatic islets develop overt diabetes with hyperglycemia.
investigation of common variable immunodeficiency (CVID (zeige TNFRSF13B ELISA Kits)) from 2 German families; report on the occurrence of a common and one novel truncating IFNK mutation in cases with CVID (zeige TNFRSF13B ELISA Kits); the frequency distribution of c.30_31insTGTT in cases and controls as well as the observed segregation patterns in CVID (zeige TNFRSF13B ELISA Kits) families exclude IFNK mutations as major risk factor in CVID (zeige TNFRSF13B ELISA Kits)
These results suggest that high-risk human papillomavirus 31 target interferon kappa to prevent Sp100 (zeige SP100 ELISA Kits) expression and identify Sp100 (zeige SP100 ELISA Kits) as an interferon (zeige IFNA ELISA Kits)-stimulated gene with anti-human papillomavirus activity.
This study demonstrates that E2 proteins of high risk human papillomavirus reduce STING and IFN-kappa transcription.
The viral E6 and E7 oncogenes are sufficient for interferon-kappa repression, with E6 being mainly responsible.
IFN-kappa is down-regulated in cervical keratinocytes harboring HPV, which may be a contributing factor in the progression of a cervical lesion
Studied IFNK single nucleotide polymorphisms in 3982 Systemic lupus erythematosus cases and 4275 controls.
IFN-kappa is able to directly modulate cytokine release from monocytes and dendritic cells, inhibit inducible IL-12 (zeige IL12A ELISA Kits) release from monocytes, and bind strongly to heparin.
This is the first report showing an epigenetic silencing of type I IFN after HPV16 oncogene (zeige RAB1A ELISA Kits) expression
This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.
, interferon kappa
, interferon-like protein