Insulin-Degrading Enzyme (IDE) ELISA Kits

IDE encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and k. Zusätzlich bieten wir Ihnen Insulin-Degrading Enzyme Antikörper (136) und Insulin-Degrading Enzyme Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
IDE 15925  
IDE 25700 P35559
IDE 3416 P14735
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Top Insulin-Degrading Enzyme ELISA Kits auf antikoerper-online.de

Showing 10 out of 50 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Ratte 0.112 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$608.00
Details
Human 0.59 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$560.00
Details
Maus 0.064 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$576.00
Details
Meerschweinchen 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Kaninchen 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Schwein 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Huhn 1.875 ng/mL 3.125-200 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Affe 1.0 pg/mL 250-5000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Hund 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Schaf
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details

Am meisten referenzierte Insulin-Degrading Enzyme ELISA Kits

  1. Rat (Rattus) IDE ELISA Kit für Sandwich ELISA - ABIN432402 : Perianes-Cachero, Canelles, Aguado-Llera, Frago, Toledo-Lobo, Carrera, Cacabelos, Chowen, Argente, Arilla-Ferreiro, Barrios: Reduction in Aβ-induced cell death in the hippocampus of 17β-estradiol-treated female rats is associated with an increase in IGF-I signaling and somatostatinergic tone. in Journal of neurochemistry 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human IDE ELISA Kit für Sandwich ELISA - ABIN1110859 : Johnson, Drugan, Miller, Evans: 38 in 1991 (PubMed)

Weitere ELISA Kits für Insulin-Degrading Enzyme Interaktionspartner

Mouse (Murine) Insulin-Degrading Enzyme (IDE) Interaktionspartner

  1. elevated IDE expression, in the skeletal muscle, seems to be mediated by activation of AMPK-ACC pathway, in response to exercise

  2. IDE inhibition did notincrease amyloid formation or beta-cell loss.

  3. This study demonstrated that the Decreased IDE and IGF2 expression in the cerebral cortex of pups by early life lead exposure.

  4. Findings show a key role of Pla2g3 (zeige PLA2G3 ELISA Kits) on the reduction of IDE, and suggest that cerebrum specific increase of Pla2g3 (zeige PLA2G3 ELISA Kits) is involved in the initiation and/or progression of Alzheimer disease.

  5. Abeta (zeige APP ELISA Kits) level reduction by CALHM1 could be explained by an increase in extracellular Abeta (zeige APP ELISA Kits) degradation by insulin-degrading enzyme.

  6. Data suggest that protein restriction down-regulates expression of insulysin (insulin degrading enzyme) in liver and subsequently reduced insulin (zeige INS ELISA Kits) clearance.

  7. IDE deficiency in bone marrow-derived cells results in larger atherosclerotic lesions, increased lesion-associated Abeta (zeige APP ELISA Kits) and RAGE (zeige AGER ELISA Kits), and higher serum cholesterol in male, Ldlr (zeige LDLR ELISA Kits)(-/-) mice.

  8. The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of alpha-synuclein levels in beta-cells.

  9. this study identified an upstream promoter element which blocks the reverse transcription of mouse IDE.

  10. Data show that in the absence of insulin-degrading enzyme (IDE), full-length calcitonin gene-related peptide (CGRP (zeige CALCA ELISA Kits)) levels are elevated in vivo.

Human Insulin-Degrading Enzyme (IDE) Interaktionspartner

  1. These results support the hypothesis that IDE gene expression in different areas of Alzheimer's patient's brains.

  2. People with allelic variation in four genes related to cardiovascular diseases and metabolism were more likely to die: apolipoprotein (APO (zeige C9orf3 ELISA Kits))C1 GG and AG carriers, APOE (zeige APOE ELISA Kits) varepsilon4 carriers, insulin-degrading enzyme (IDE) TC carriers, and phosphatidylinositol 3-kinase (PI3KCB) GG carriers.

  3. Data suggest the possibility of development of insulin-degrading enzyme (IDE)-based drugs for the treatment of the late-onset form of Alzheimer's disease (AD).

  4. the mechanistic and molecular features of IDE-26S proteasome (zeige Psmd4 ELISA Kits) interaction in a cell experimental model, is reported.

  5. No significant associations have been found between other IDE gene single nucleotide polymorphisms of rs4646953, rs2251101 and rs1544210 with Alzheimer disease.

  6. results demonstrate that the polymorphisms rs1887922 and rs1999764 of the IDE gene are associated with late-onset Alzheimer disease susceptibility in the Xinjiang Han population

  7. Cognitive impairment is more frequent among those exposed to the C allele of the rs2209972 SNP of the insulin degrading enzyme gene.

  8. IDE does not play a major role in MHC class I antigen processing, confirming the dominant and almost exclusive role of the proteasome in cytosolic production of MHC class I ligands.

  9. using combinational in silico investigations, study identified that pathogenic nonsynonymous mutations corresponding to p.I54F, p.P122T, p.T533R, p.P581A and p.Y609A have more potential role in structural and functional deviations of IDE activity

  10. Our study provided evidence to IDE, PON1 (zeige PON1 ELISA Kits), WFS1 (zeige WFS1 ELISA Kits), POU2F1 (zeige POU2F1 ELISA Kits), IL1alpha (zeige IL1A ELISA Kits) and IL1beta (zeige IL1B ELISA Kits) associated with T2D in Pakistanis.

Insulin-Degrading Enzyme (IDE) Antigen-Profil

Beschreibung des Gens

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

Genbezeichner und Symbole assoziert mit IDE

  • insulin degrading enzyme (IDE) Antikörper
  • insulin-degrading enzyme (ide) Antikörper
  • insulin-degrading enzyme (LOC591315) Antikörper
  • insulin-degrading enzyme (CC1G_01115) Antikörper
  • insulin-degrading enzyme (Bm1_26615) Antikörper
  • insulin-degrading enzyme (PTRG_10875) Antikörper
  • metallopeptidase (SJAG_01430) Antikörper
  • insulin-degrading enzyme (EBI_21700) Antikörper
  • insulin-degrading enzyme (VDBG_06702) Antikörper
  • insulin-degrading enzyme (LOAG_08082) Antikörper
  • insulin-degrading enzyme (PGTG_04982) Antikörper
  • insulin-degrading enzyme (Tsp_00424) Antikörper
  • insulin degrading enzyme (Ide) Antikörper
  • 1300012G03Rik Antikörper
  • 4833415K22Rik Antikörper
  • AA675336 Antikörper
  • AI507533 Antikörper
  • IDE Antikörper
  • INSDEGM Antikörper
  • INSULYSIN Antikörper
  • zgc:162603 Antikörper

Bezeichner auf Proteinebene für IDE

insulysin , insulin-degrading enzyme , insulin-degrading enzyme-like , insulin protease , insulinase , Abeta-degrading protease

GENE ID SPEZIES
450608 Pan troglodytes
561390 Danio rerio
591315 Strongylocentrotus purpuratus
698640 Macaca mulatta
6009544 Coprinopsis cinerea okayama7130
6100223 Brugia malayi
6349187 Pyrenophora tritici-repentis Pt-1C-BFP
7051385 Schizosaccharomyces japonicus yFS275
8641122 Enterocytozoon bieneusi H348
9537184 Verticillium alfalfae VaMs.102
100071303 Equus caballus
100385143 Callithrix jacchus
100434053 Pongo abelii
100482236 Ailuropoda melanoleuca
9945508 Loa loa
10530847 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10901673 Trichinella spiralis
15925 Mus musculus
25700 Rattus norvegicus
3416 Homo sapiens
477768 Canis lupus familiaris
100341888 Oryctolagus cuniculus
100719651 Cavia porcellus
423814 Gallus gallus
100155309 Sus scrofa
523752 Bos taurus
101104194 Ovis aries
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