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ITPA encodes an inosine triphosphate pyrophosphohydrolase. Zusätzlich bieten wir Ihnen Inosine Triphosphatase Proteine (22) und Inosine Triphosphatase Kits (13) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 78 products:
Human Monoclonal ITPA Primary Antibody für ELISA - ABIN517268
Vroemen, Munnix, Bakker, Bierau, Huts, Leers: A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012
In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.
The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP
Four gene signature (PTEN, PIK3C2A (zeige PIK3C2A Antikörper), ITPA and BCL3 (zeige BCL3 Antikörper)) is an independent prognostic factors of both overall survival and disease-free survival in clear-cell renal-cell carcinoma (zeige MOK Antikörper).
Inosine triphosphatase polymorphism appeared to correlate with anemia in- cidence and RBV dose reduction during SOF (zeige GJA1 Antikörper)/RBV therapy.
Inosine triphosphatase (IPTA) rs1127354 variants but not rs7270101 were found in Chinese patients infected with chronic hepatitis C. IPTA rs1127354 variants and related ITPase were not only related with ribavirin-induced hemolytic anemia but also directly affected the virological response to pegylated interferon (zeige IFNA Antikörper) plus ribavirin combination therapy in Chinese chronic hepatitis C virus-infected patients.
This study concluded that HIV-infection seems to be interfering with the nucleotide metabolism in leukocytes, including CD4 (zeige CD4 Antikörper) lymphocytes, by decreasing ITPase expression, independently of ITPA genotype.
A high prevalence of the ITPA polymorphisms associated with ribavirin-induced hemolytic anemia was found in Mexican Native Amerindians.
ITPA gene is associated with protection of anemia in patients with chronic hepatitis during antiviral therapy.
We concluded that ITPase activity plays an important function and that ATP concentration changes due to therapy are related to the Hb decreasing mechanism in the early period of therapy with HCV treatment
The aim of the study was to investigate frequencies of TPMT (zeige TPMT Antikörper) and ITPA polymorphisms in Lithuanian inflammatory bowel disease patients and analyze their association with azathioprine-related adverse events.
ITPA polymorphism was associated with RBV-induced anemia and thrombocytopenia in Egyptian patients with hepatitis C virus genotype 4 infection.
Hyperbilirubinemia develops at early time points after simeprevir administration in most cases and is dependent on the ITPA genotype.
This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
inosine triphosphate pyrophosphatase
, inosine triphosphatase
, non-canonical purine NTP pyrophosphatase
, non-standard purine NTP pyrophosphatase
, nucleoside triphosphate pyrophosphatase
, nucleoside-triphosphate diphosphatase
, nucleoside-triphosphate pyrophosphatase
, inosine triphosphatase-A
, inosine triphosphate pyrophosphohydrolase
, putative oncogene protein HLC14-06-P
, inosine triphosphatase A
, Inosine triphosphatase
, Non-canonical purine NTP pyrophosphatase
, Non-standard purine NTP pyrophosphatase
, Nucleoside-triphosphate diphosphatase
, Nucleoside-triphosphate pyrophosphatase
, hypothetical protein