anti-Inosine Triphosphatase (ITPA) Antikörper

ITPA encodes an inosine triphosphate pyrophosphohydrolase. Zusätzlich bieten wir Ihnen Inosine Triphosphatase Proteine (24) und Inosine Triphosphatase Kits (14) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ITPA 16434 Q9D892
ITPA 311422 D3ZW55
ITPA 3704 Q9BY32
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Top anti-Inosine Triphosphatase Antikörper auf antikoerper-online.de

Showing 10 out of 90 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of ITPA Antibody (N-term) (ABIN651135) in A375 cell line lysates (35 µg/lane). ITPA (arrow) was detected using the purified polyclonal antibody. ITPA Antibody (N-term) (ABIN651135) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image ITPase antibody [N1C3] detects ITPase protein at cytosol on Ca922 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Ca922 xenograft. ITPase antibody [N1C3] , dilution: 1:500. WB Image Sample(30 ug whole cell lysate) A:293T B:Hep G2 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of Hepg2 whole cell lysates, using ITPA Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276621 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: ITPA Antibody [NBP1-32494] - Sample(30 ug whole cell lysate)A:293TB:Hep G2 (GTX27900)12% SDS PAGE, antibody diluted at 1:1000. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert WB ITPA Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ITPA antibody detected the ITPA protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$360.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of lysates from A375,Hela,HepG2 cell line,mouse brain,rat liver tissue lysate(from left to right), using ITPA Antibody (N-term)(ABIN5968918). ABIN5968918 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane. 80 μL Anmelden zum Anzeigen 10 bis 11 Tage
$120.00
Details
Maus Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using ITPA antibody. 100 μL Anmelden zum Anzeigen 13 bis 14 Tage
$452.24
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using ITPA antibody (ABIN5970563) at 1:3000 dilution. 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details

Am meisten referenzierte anti-Inosine Triphosphatase Antikörper

  1. Human Monoclonal ITPA Primary Antibody für ELISA - ABIN517268 : Vroemen, Munnix, Bakker, Bierau, Huts, Leers: A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012 (PubMed)

Weitere Antikörper gegen Inosine Triphosphatase Interaktionspartner

Mouse (Murine) Inosine Triphosphatase (ITPA) Interaktionspartner

  1. The authors analysed ITPA-deficient human and mouse cells, and revealed that ITPA deficiency induces MLH1 (zeige MLH1 Antikörper)/PMS2 (zeige PMS2 Antikörper)- and p53 (zeige TP53 Antikörper)-dependent growth arrest and DNA instability in mammalian cells.

  2. In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.

  3. The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP

Human Inosine Triphosphatase (ITPA) Interaktionspartner

  1. Inosine triphosphate pyrophosphatase dephosphorylates ribavirin triphosphate, and reduced enzymatic activity potentiates mutagenesis in hepatitis C virus.

  2. This study suggests that the polymorphisms in the ITPA gene influence the severity of anaemia during the first month of a DAA/RBV-based treatment in HCV-related cirrhosis.

  3. baseline testing of this single ITPA SNP might help to identify the subset of patients with the greatest risk for experiencing RBV-induced anaemia, which may be particularly helpful in those with underlying cardiovascular disease. In such patients, RBV-sparing regimens should be preferred.

  4. The authors analysed ITPA-deficient human and mouse cells, and revealed that ITPA deficiency induces MLH1 (zeige MLH1 Antikörper)/PMS2 (zeige PMS2 Antikörper)- and p53 (zeige TP53 Antikörper)-dependent growth arrest and DNA instability in mammalian cells.

  5. ITPA variant rs1127354C>A significantly predict RBV-induced anaemia during the first 3 months of treatment and it is recommended to be assessed before RBV administration

  6. The ITPA gene polymorphism rs1127354 heterozygous genotype (CA) may influence Hemoglobin levels and protect against hemolytic anemia during ribavirin containing regimens for hepatitis C

  7. Four gene signature (PTEN, PIK3C2A (zeige PIK3C2A Antikörper), ITPA and BCL3 (zeige BCL3 Antikörper)) is an independent prognostic factors of both overall survival and disease-free survival in clear-cell renal-cell carcinoma (zeige MOK Antikörper).

  8. Inosine triphosphatase polymorphism appeared to correlate with anemia in- cidence and RBV dose reduction during SOF (zeige GJA1 Antikörper)/RBV therapy.

  9. Inosine triphosphatase (IPTA) rs1127354 variants but not rs7270101 were found in Chinese patients infected with chronic hepatitis C. IPTA rs1127354 variants and related ITPase were not only related with ribavirin-induced hemolytic anemia but also directly affected the virological response to pegylated interferon plus ribavirin combination therapy in Chinese chronic hepatitis C virus-infected patients.

  10. This study concluded that HIV-infection seems to be interfering with the nucleotide metabolism in leukocytes, including CD4 (zeige CD4 Antikörper) lymphocytes, by decreasing ITPase expression, independently of ITPA genotype.

Inosine Triphosphatase (ITPA) Antigen-Profil

Protein Überblick

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit ITPA

  • inosine triphosphatase (itpa) Antikörper
  • inosine triphosphatase (ITPA) Antikörper
  • inosine triphosphatase (LOC733043) Antikörper
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa) Antikörper
  • inosine triphosphatase (Itpa) Antikörper
  • Inosine triphosphate pyrophosphatase (pco148511) Antikörper
  • inosine triphosphatase S homeolog (itpa.S) Antikörper
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (itpa) Antikörper
  • 2010016I08Rik Antikörper
  • AU020102 Antikörper
  • C20orf37 Antikörper
  • DDBDRAFT_0215619 Antikörper
  • DDBDRAFT_0238062 Antikörper
  • DDB_0215619 Antikörper
  • DDB_0238062 Antikörper
  • dJ794I6.3 Antikörper
  • HLC14-06-P Antikörper
  • Itp Antikörper
  • ITPase Antikörper
  • NTPase Antikörper
  • si:ch73-18j6.1 Antikörper
  • si:dkey-19f21.1 Antikörper

Bezeichner auf Proteinebene für ITPA

inosine triphosphate pyrophosphatase , inosine triphosphatase , ITPase , NTPase , non-canonical purine NTP pyrophosphatase , non-standard purine NTP pyrophosphatase , nucleoside triphosphate pyrophosphatase , nucleoside-triphosphate diphosphatase , nucleoside-triphosphate pyrophosphatase , inosine triphosphatase-A , inosine triphosphate pyrophosphohydrolase , putative oncogene protein HLC14-06-P , inosine triphosphatase A , Inosine triphosphatase , Non-canonical purine NTP pyrophosphatase , Non-standard purine NTP pyrophosphatase , Nucleoside-triphosphate diphosphatase , Nucleoside-triphosphate pyrophosphatase , PCO148511_ov , hypothetical protein , pco148511(169)

GENE ID SPEZIES
8625642 Dictyostelium discoideum AX4
100345066 Oryctolagus cuniculus
733043 Bombyx mori
100157088 Sus scrofa
16434 Mus musculus
311422 Rattus norvegicus
3704 Homo sapiens
613653 Bos taurus
100283993 Zea mays
424390 Gallus gallus
735008 Xenopus laevis
557834 Danio rerio
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